HOME >> BIOLOGY >> NEWS
Finding the right mix: A biomaterial blend library

From dental implants to hip replacements, biomaterials have become big business. But scientists pursuing this modern medical revolution share a basic challenge: biocompatibility. How will a biomaterial on the lab bench actually work inside the human body? Will a patient accept the new material or suffer an inflammatory response? And can that material survive in a human's complex system?

To tackle such questions, researchers at the National Institute of Standards and Technology (NIST) and the New Jersey Center for Biomaterials (NJCB) at Rutgers University have developed new methods to analyze the interactions between cells and biomaterials. Their work could lead to inexpensive techniques for building better biomaterials.

Polymers derived from the amino acid tyrosine make up a broad class of degradable biomaterials under investigation. Such materials provide a temporary scaffold for cells to grow and tissue to regenerate. In a 2006 study* presented at the national meeting of the American Chemical Society in September, the researchers analyzed how two types of model cells--immune cells known as macrophages and bone cells known as osteoblasts--responded to changes in the composition of thin films made of these tyrosine-derived polymers. In practice, many biomaterials are made from blends of polymers to achieve specific material properties. Optimizing the blend composition is often a difficult and time-consuming task. As the blends gained a higher or lower proportion of a respective material, the cells around them react by changing shape, ultimately increasing or decreasing contact with the films. In the body, such cell-material dynamics are critically important to the outcome--determining whether a biomaterial leads to inflammation or abnormal cell growth, for example.

The new study represents an innovative line of research. Working with NJCB, NIST scientists have developed a method for constructing "scaffold libraries" --collections of
'"/>

Contact: Mark Bello
mark.bello@nist.gov
301-975-3776
National Institute of Standards and Technology (NIST)
27-Oct-2006


Page: 1 2

Related biology news :

1. Finding protection from tumor growth in unexpected places
2. Finding the white wine difference
3. Finding an answer to Darwins Dilemma
4. Finding a cure for cancer: The holy grail of science
5. Finding paves way for better treatment of autoimmune disease
6. Finding about cellular microtubule rigidity could lead to development of new nano-materials
7. Findings by Einstein scientists reveal possible strategy against obesity, diabetes and infertility
8. Finding of a new molecular marker of resistance to chemotherapy in breast cancer
9. Finding a cellular Neverland: How stem cells stay childlike
10. Finding a virus is not all bad news
11. Finding life on Mars and outer space begins by examining Earths inner space

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/10/2020)... ... July 08, 2020 , ... Overcoming Comparability Issues ... An FDAnews Webinar, Wednesday, July 22, 2020 • 1:30 p.m.-3:00 p.m. EDT, ... the most effective way to complete one? Will the study comply with all ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... B.V. (MBS) has announced a publication detailing the use of its revolutionary ... polymerase chain reaction (RT-PCR) in 16 minutes. The article, titled "Ultra-fast one-step ...
(Date:6/28/2020)... ... , ... In an upcoming episode scheduled for the fall of 2020, Advancements ... (POCT). Check local listings for more info. , Today, the majority of testing is ... labs throughout the country. Results are then available several days later. Now, in an ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... , ... True Terpenes , the leading platform for terpene innovation, research ... research the medical potential of terpenes and the potential entourage effect , where ... is focused on expanding the recently launched line of effects-based terpenes - Terpology ...
(Date:8/7/2020)... Texas (PRWEB) , ... August 06, 2020 , ... ... and DNA vaccine industries, announces it has closed on the purchase of greenfield ... Park in Conroe, TX and includes over 21 acres in the initial acquisition, ...
(Date:7/31/2020)... Mass. (PRWEB) , ... July 29, 2020 , ... ... highly reliable, solid-state radar transmitter systems that can be configured to drive Klystrons, ... single controller that can drive one or two switches in a push-pull configuration; ...
(Date:7/31/2020)... , ... July 30, 2020 ... ... cloud-based software for the life sciences industry, today announced the release of ... designed specifically for Medical Science Liaisons (MSLs) and other field medical professionals. ...
Breaking Biology Technology:
Cached News: