HOME >> BIOLOGY >> NEWS
Finding the right mix: A biomaterial blend library

From dental implants to hip replacements, biomaterials have become big business. But scientists pursuing this modern medical revolution share a basic challenge: biocompatibility. How will a biomaterial on the lab bench actually work inside the human body? Will a patient accept the new material or suffer an inflammatory response? And can that material survive in a human's complex system?

To tackle such questions, researchers at the National Institute of Standards and Technology (NIST) and the New Jersey Center for Biomaterials (NJCB) at Rutgers University have developed new methods to analyze the interactions between cells and biomaterials. Their work could lead to inexpensive techniques for building better biomaterials.

Polymers derived from the amino acid tyrosine make up a broad class of degradable biomaterials under investigation. Such materials provide a temporary scaffold for cells to grow and tissue to regenerate. In a 2006 study* presented at the national meeting of the American Chemical Society in September, the researchers analyzed how two types of model cells--immune cells known as macrophages and bone cells known as osteoblasts--responded to changes in the composition of thin films made of these tyrosine-derived polymers. In practice, many biomaterials are made from blends of polymers to achieve specific material properties. Optimizing the blend composition is often a difficult and time-consuming task. As the blends gained a higher or lower proportion of a respective material, the cells around them react by changing shape, ultimately increasing or decreasing contact with the films. In the body, such cell-material dynamics are critically important to the outcome--determining whether a biomaterial leads to inflammation or abnormal cell growth, for example.

The new study represents an innovative line of research. Working with NJCB, NIST scientists have developed a method for constructing "scaffold libraries" --collections of
'"/>

Contact: Mark Bello
mark.bello@nist.gov
301-975-3776
National Institute of Standards and Technology (NIST)
27-Oct-2006


Page: 1 2

Related biology news :

1. Finding protection from tumor growth in unexpected places
2. Finding the white wine difference
3. Finding an answer to Darwins Dilemma
4. Finding a cure for cancer: The holy grail of science
5. Finding paves way for better treatment of autoimmune disease
6. Finding about cellular microtubule rigidity could lead to development of new nano-materials
7. Findings by Einstein scientists reveal possible strategy against obesity, diabetes and infertility
8. Finding of a new molecular marker of resistance to chemotherapy in breast cancer
9. Finding a cellular Neverland: How stem cells stay childlike
10. Finding a virus is not all bad news
11. Finding life on Mars and outer space begins by examining Earths inner space

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/30/2020)... ... April 28, 2020 , ... Ever a responsive ... in providing timely and critical information to life science organizations as they navigate ... safety concerns. , “Providing the most up-to-date actionable guidance and information has been ...
(Date:4/26/2020)... ... ... A team of researchers at the Icahn School of Medicine at Mount Sinai, ... causes coronavirus disease (COVID-19). This antibody is intended to block the virus from entering ... efforts are being led by Mone Zaidi, MD, PhD, MACP, Director of the Mount ...
(Date:4/22/2020)... SANTA BARBARA, Calif. (PRWEB) , ... April 21, ... ... consulting firm driving digital transformation and innovation in technology and compliance, announces a ... Powered by a best-in-class trio of alliances – Box, ComplianceQuest, and USDM Life ...
Breaking Biology News(10 mins):
(Date:5/1/2020)... ... April 30, 2020 , ... ... honoring the businesses, policies, projects, and concepts that are actively engaged and deeply ... living cells, which has taken out the top prize in the Experimental category. ...
(Date:4/23/2020)... ... April 22, 2020 , ... ... providers to protect themselves from COVID-19. Virginia has only been receiving 50% to ... Management Association (FEMA). , As Governor Northam told the Virginia Mercury, “While we ...
(Date:4/22/2020)... ... April 21, 2020 , ... Aniara Diagnostica is ... FXIII. , Aniara Diagnostica, a multi-national distributor of diagnostic and research agents, as ... for product quality and cost-efficient delivery. , For Research Use Only. ...
(Date:4/18/2020)... ... April 17, 2020 , ... ... Business Innovation Research (SBIR) program to support the expansion of its digital health ... NSF, which conducts a rigorous merit-based review process, adds to NeuroFlow’s recent ...
Breaking Biology Technology:
Cached News: