HOME >> BIOLOGY >> NEWS
Floating and spiky

With the aid of complex computer simulations, scientists at the Max Planck Institute of Colloids and Interfaces in Potsdam and at the University of Heidelberg have discovered how the shape and distribution of certain sticky areas on the cell affect its adhesion in blood vessels. According to this research, neither the number nor the size of these adhesive areas are the most important parameters; the most crucial factor is how far they extend from the cell surface. White blood corpuscles and red blood cells infected with malaria are seen to use this spiky hedgehog-like structure for their adhesion strategy (Physical Review Letters, 28. September 2006).

Blood is the universal means with which different types of cells are transported in our bodies. Its movement is determined by hydrodynamic forces. The cells anchor themselves to the walls of the blood vessels in the target tissue with the aid of special adhesive molecules, which are also called receptors. In many cases these receptors are grouped in the cell surface in nanometer-sized patches. The adhesion process is based on the key and lock principle: as a rule, an adhesion molecule only bonds with specific partners. This guarantees that the cells are only brought to a halt where they are to fulfill their biological function.

These processes are of great relevance to medicine. For example, red blood corpuscles infected with malaria stick to blood vessel walls to escape destruction in the spleen and patrolling white blood corpuscles dock with the blood vessel walls in order to seek out foreign bodies in the adjacent tissue. These "wandering adhesive cells" also include stem cells, which move from the bone marrow to their target tissue, and cancer cells which metastasize in the body.

To understand these processes better, it is necessary to show and track the interplay of hydrodynamics and molecular adhesion patches in detail. To do this, scientists at the Max Planck Institute of Colloi
'"/>

Contact: Christian Korn
Christian.Korn@mpikg.mpg.de
49-331-567-9622
Max-Planck-Gesellschaft
3-Nov-2006


Page: 1 2 3

Related biology news :

1. Floating lovers count too -- in the health of eagle populations

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: