HOME >> BIOLOGY >> NEWS
Fly and worm models to teach researchers about human biology and medicine

In an effort to understand every part of the genome needed for organisms to develop and thrive, the National Human Genome Research Institute, part of the National Institutes of Health, today announced the first grants in a four-year, $57 million scientific mission to identify all functional elements in the genomes of the fruit fly and round worm.

The effort will build upon the foundation laid by the ENCyclopedia Of DNA Elements (ENCODE) consortium, which is preparing to build a comprehensive catalog, or "parts list," of all elements in the human genome crucial to biological function. In addition to genes that code for proteins, these functional elements include: non-protein-coding genes; regulatory elements involved in the control of gene transcription; and DNA sequences that mediate the structure and dynamics of chromosomes.

"We are making great strides in identifying functional elements in the human genome, but we still don't know much about their biological relevance. This parallel effort in the fruit fly and worm genomes will provide us with information about the functional landscape of two key model organisms, which should aid our efforts to tackle such questions in humans," said NHGRI Director Francis S. Collins, M.D., Ph.D.

Over the past several years, ENCODE researchers have collaborated in a pilot project to develop and use innovative methods and technologies to find functional elements in about 1 percent of the human genome. The new effort, dubbed model organism ENCODE (modENCODE), will take advantage of many of these methods and technologies. However, rather than using the tools on the large and complex human genome, researchers will apply them to the smaller, and therefore more manageable, genomes of the fruit fly ("Drosophila melanogaster") and the round worm ("Caenorhabditis elegans"). The scientific community relies heavily on these model organisms to identify common genes,
'"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
14-May-2007


Page: 1 2 3 4

Related biology news :

1. Huntingtons disease study shows animal models on target
2. Scripps research scientists show protein accelerates breast cancer progression in animal models
3. Better chemistry through living models
4. Arctic ice retreating more quickly than computer models project
5. Statin treatment improves spatial memory in mouse models of Alzheimers
6. Duke geologists book assails unrealistic mathematical models
7. Rotting leaf litter study could lead to more accurate climate models
8. Quantum biology -- Powerful computer models reveal key biological mechanism
9. Some key laboratory breast cancer cell lines are, indeed, good models for the real disease
10. Prediction models help identify increased risk of gene mutation linked with colorectal cancer
11. Whats nature worth? New computer models tell all

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... July 01, 2020 , ... ... phase 1a findings of Neihulizumab, a biologic for the treatment of steroid-refractory acute ... Led by hemato-oncologist Dr. Paul J Martin of the Fred Hutchinson Cancer Research ...
(Date:7/1/2020)... SOMERSET, N.J. (PRWEB) , ... July 01, 2020 ... ... today announced that it had completed the purchase of Teva-Takeda Pharmaceuticals’ packaging facility ... with the company’s existing Japanese clinical supply facility located in Kakegawa, the new ...
(Date:6/28/2020)... (PRWEB) , ... June 25, ... ... of enterprise software solutions for biopharmaceutical R&D, today announced that it has ... developing innovative, full-length multispecific antibodies (Multiclonics®), to support their translational and clinical ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted ... will cover the history of eSource, the reasons it did not take off as ... to site source, the industry is moving towards capturing data electronically for clinical trials ...
(Date:7/18/2020)... ... , ... “We are thrilled to deliver this new technology to the industry” ... kind on the market and we were pleased that the IFT jury recognized that.” ... ingredients, creating a natural way to extend the shelf life and improve the safety ...
(Date:7/10/2020)... ... July 09, 2020 , ... In most research using the ... pigment formation in zebrafish embryos, maintaining optical transparency to facilitate microscopic imaging. Over ... been using the zebrafish model to investigate the causes of leukaemia and its ...
(Date:7/1/2020)... ... June 29, 2020 , ... ... competitively procured purchasing contracts to its membership, recently named BioFit Engineered Products ... with the opportunity to purchase ergonomic seating, cafeteria tables, book trucks and carts ...
Breaking Biology Technology:
Cached News: