HOME >> BIOLOGY >> NEWS
Fly and worm models to teach researchers about human biology and medicine

In an effort to understand every part of the genome needed for organisms to develop and thrive, the National Human Genome Research Institute, part of the National Institutes of Health, today announced the first grants in a four-year, $57 million scientific mission to identify all functional elements in the genomes of the fruit fly and round worm.

The effort will build upon the foundation laid by the ENCyclopedia Of DNA Elements (ENCODE) consortium, which is preparing to build a comprehensive catalog, or "parts list," of all elements in the human genome crucial to biological function. In addition to genes that code for proteins, these functional elements include: non-protein-coding genes; regulatory elements involved in the control of gene transcription; and DNA sequences that mediate the structure and dynamics of chromosomes.

"We are making great strides in identifying functional elements in the human genome, but we still don't know much about their biological relevance. This parallel effort in the fruit fly and worm genomes will provide us with information about the functional landscape of two key model organisms, which should aid our efforts to tackle such questions in humans," said NHGRI Director Francis S. Collins, M.D., Ph.D.

Over the past several years, ENCODE researchers have collaborated in a pilot project to develop and use innovative methods and technologies to find functional elements in about 1 percent of the human genome. The new effort, dubbed model organism ENCODE (modENCODE), will take advantage of many of these methods and technologies. However, rather than using the tools on the large and complex human genome, researchers will apply them to the smaller, and therefore more manageable, genomes of the fruit fly ("Drosophila melanogaster") and the round worm ("Caenorhabditis elegans"). The scientific community relies heavily on these model organisms to identify common genes,
'"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
14-May-2007


Page: 1 2 3 4

Related biology news :

1. Huntingtons disease study shows animal models on target
2. Scripps research scientists show protein accelerates breast cancer progression in animal models
3. Better chemistry through living models
4. Arctic ice retreating more quickly than computer models project
5. Statin treatment improves spatial memory in mouse models of Alzheimers
6. Duke geologists book assails unrealistic mathematical models
7. Rotting leaf litter study could lead to more accurate climate models
8. Quantum biology -- Powerful computer models reveal key biological mechanism
9. Some key laboratory breast cancer cell lines are, indeed, good models for the real disease
10. Prediction models help identify increased risk of gene mutation linked with colorectal cancer
11. Whats nature worth? New computer models tell all

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/31/2020)... FRANCISCO (PRWEB) , ... July 30, 2020 , ... ... maturing prescription digital therapeutics product portfolio with a near term focus on Type ... biotech and pharma commercialization experience across multiple therapeutic areas and classes. As Chief ...
(Date:7/18/2020)... ... July 16, 2020 , ... ... effectiveness of the Invictus Medical Neoasis™ active noise control device to attenuate typical ... that the Neoasis™ device attenuated the alarm sounds from patient monitors, ventilators and ...
(Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... Latest on Cell and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, ... need a comparability study, but what is the most effective way to complete ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine today revealed ... prestigious ranking of the nation’s fastest-growing private companies. The list represents a unique ... independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many other well-known ...
(Date:8/12/2020)... ... August 11, 2020 , ... Modality ... for free its new white paper – Simulated Transport Methodologies. Regulatory expectations ... biologics licensing application (BLA). In response, Modality Solutions shares an explanation of ...
(Date:8/7/2020)... Texas (PRWEB) , ... August 06, 2020 , ... ... and DNA vaccine industries, announces it has closed on the purchase of greenfield ... Park in Conroe, TX and includes over 21 acres in the initial acquisition, ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... Introducing Ardent ... for transformative growth, , Known as MediVet Biologics since its ... , The new Ardent Animal Health will build on its base of ...
Breaking Biology Technology:
Cached News: