Fly and worm models to teach researchers about human biology and medicine

tellectual discussions and quality of data analysis. The modENCODE grant recipients, the focus of their research and their approximate funding levels are:

SUSAN CELNIKER, PH.D., LAWRENCE BERKELEY NATIONAL LABORATORY, UNIVERSITY OF CALIFORNIA AT BERKELEY -- "D. melanogaster". "Comprehensive Characterization of the Drosophila Transcriptome" -- First-year funds, $3.6 million; total funds, $14.5 million.

STEVEN HENIKOFF, PH.D., FRED HUTCHINSON CANCER RESEARCH CENTER, SEATTLE -- "C. elegans and D. melanogaster". "Genome-Wide Profiling of Histone Variants in Drosophila and Caenorhabditis" -- First-year funds, $429,000; total funds, $1.7 million.

GARY KARPEN, PH.D., LAWRENCE BERKELEY NATIONAL LABORATORY, UNIVERSITY OF CALIFORNIA AT BERKELEY. -- "D. melanogaster". "Genome-Wide Mapping of Chromosomal Proteins in Drosophila" -- First -year funds, $1.8 million; total funds, $7.2 million.

ERIC LAI, PH.D., MEMORIAL SLOAN-KETTERING CANCER CENTER, SLOAN-KETTERING INSTITUTE, NEW YORK. -- "D. melanogaster". "Annotation of the Small RNA/microRNA Component in the Drosophila Genome" -- First-year funds, $470,000; total funds, $1.9 million.

JASON LIEB, PH.D., THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL. -- "C. elegans". "Identification of DNA Elements Governing Chromatin Function in C. elegans" -- First-year funds, $1.8 million; total funds, $7.3 million.

DAVID MACALPINE, PH.D., DUKE UNIVERSITY, DURHAM, N.C. -- "D. melanogaster". "The Systematic Identification and Analysis of Replication Origins in Drosophila" -- First-year funds, $469,000; total funds, $1.9 million.

FABIO PIANO, PH.D., NEW YORK UNIVERSITY, NEW YORK. -- "C. elegans". "Encyclopedia of "C. elegans" 3'UTRs and Their Regulatory Elements" -- First-year funds, $397,000; total funds, $1.6 million.

MICHAEL SNYDER, PH.D., YALE UNIVERSITY, NEW HAVEN, CONN. - "C. elegans". "Global Identification of Transcription Fact

Contact: Geoff Spencer
NIH/National Human Genome Research Institute

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