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Folate and B12 may influence cognition in seniors

itamin B12 deficiency, who may be more numerous than once realized. There are also indications that too much folic acid and too little B12 is a general phenomenon that affects other systems in the body, and might be a factor in some other diseases."

As with any epidemiological study, Morris cautions that the results show association and not causation. She also notes that because the study only measured levels of total folate in the blood, it is uncertain whether the results were due to unmetabolized folic acid in the body. "We encourage further studies of these relationships and their underlying mechanisms," write Morris and her colleagues at Tufts. "We hope our findings both inform the continuing debate about folic acid fortification and influence future efforts to detect and treat low vitamin B12 status among seniors."


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Contact: Siobhan Gallagher
siobhan.gallagher@tufts.edu
617-636-6586
Tufts University
9-Feb-2007


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