HOME >> BIOLOGY >> NEWS
Fruit fly gene research may shed light on human disease processes

some does not influence sex. Instead, two X chromosomes signal the fly to be female, and one X chromosome means it will be male."

A chromosome is a single DNA molecule that may contain different units of inheritance called genes, along with proteins that help to activate these genes under certain conditions.

Even though it is the presence or absence of the human Y chromosome that directs sex development, human females still need to determine how many X chromosomes they have in each cell. They do this to ensure that similar amounts of the proteins encoded on the X chromosomes are produced in each sex. Failure to properly count X chromosomes is lethal to embryos of mammals and flies. That's why biologists want to understand the process of "chromosome counting."

Early in his career, Erickson was part of the research team that identified the genes involved in counting Drosophilia sex chromosomes. Now, he and Avila have made another breakthrough, identifying a signaling pathway outside the cell that helps trigger a cascade of proteins to ensure embryos remain either male or female once their sex has been determined, as well as help in the chromosome-counting process and in regulating other crucial cell activities.

"This signaling process is not unique to embryonic sex differentiation, but occurs in hundreds of genes throughout the body, in flies and in higher animals, too," Avila says. "Our work sheds light on signal transmission in humans."

Erickson points out that flies have evolved along with humans and that the two species are "close."

Although he is quick to point out that the group's research has no short-term practical application, he believes down the road it has important implications for human health.

"Scientists have been trying to understand how the sex of mosquitoes is determined, with an eye to eradicating those which carry diseases," he says. "Our research on fruit flies may he
'"/>

Contact: Judith White
judith-white@tamu.edu
979-845-4645
Texas A&M University
27-Mar-2007


Page: 1 2 3

Related biology news :

1. Fruit fly gene from out of nowhere is discovered
2. Fruit fly research may clean up conventional impressions of biology
3. Fruit bats are not blind as a bat
4. Survival of the rarest: Fruit flies shed light on the evolution of behavior
5. Fruit flies may pave way to new treatments for age-related heart disease
6. Fruit flies and global warming -- some like it hot
7. Fruit fly dating game provides clues to our reproductive prowess
8. Fruit juice intake among preschool children not associated with weight
9. Fruit fly study identifies gene mutation that regulates sensitivity to alcohol
10. Fruit fly aggression studies have relevance to humans, animals
11. Psst! Coffee drinkers: Fruit flies have something to tell you about caffeine

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... -- Research and Markets has announced the addition of ... their offering. The report forecasts ... grow at a CAGR of 12.28% during the period 2016-2020. ... market analysis with inputs from industry experts. The report covers the ... report also includes a discussion of the key vendors operating in ...
(Date:6/22/2016)... 22, 2016  The American College of Medical Genetics and ... Magazine as one of the fastest-growing trade shows during ... the Bellagio in Las Vegas . ... of growth in each of the following categories: net square ... number of attendees. The 2015 ACMG Annual Meeting was ranked ...
(Date:6/22/2016)... , June 22, 2016   ... management and verification solutions, has partnered with ... software solutions for Visitor Management, Self-Service Kiosks ... provides products that add functional enhancements to ... provides corporations and venues with an automated ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... June 24, 2016  Regular discussions on a range of ... between the two entities said Poloz. Speaking at ... Ottawa , he pointed to the country,s inflation target, ... government. "In certain ... institutions have common economic goals, why not sit down and ...
(Date:6/24/2016)... NC (PRWEB) , ... June 24, 2016 , ... Researchers ... the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are ... to read it now. , Diagnostic biomarkers are signposts in the blood, lung ...
(Date:6/23/2016)... CAMBRIDGE, Mass. , June 23, 2016 /PRNewswire/ ... the development of novel compounds designed to target ... compound, napabucasin, has been granted Orphan Drug Designation ... in the treatment of gastric cancer, including gastroesophageal ... cancer stemness inhibitor designed to inhibit cancer stemness ...
(Date:6/23/2016)... HOUSTON , June 23, 2016 ... agreement with the Cy-Fair Sports Association to serve ... of the agreement, Houston Methodist Willowbrook will provide ... education and connectivity with association coaches, volunteers, athletes ... partner with the Cy-Fair Sports Association and to ...
Breaking Biology Technology:
Cached News: