HOME >> BIOLOGY >> NEWS
Gene sequencing explains bioremediation 'bug'

ITHACA, N.Y. -- "The born-to-dechlorinate bug" is what Cornell University researchers called Dehalococcoides ethenogenes Strain 195 when they found the bacterium obligingly detoxifying the pollutant PCE, or perchloroethylene (a chlorinated solvent used for dry cleaning), in sludge from an Ithaca, N.Y., sewage treatment plant. Their discovery led to two questions: Might cultures of the naturally occurring microorganism serve as bioremediation agents to clean up sites where solvents such as PCE and TCE (trichloroethylene) -- used to clean metal parts -- had been dumped or spilled? And what on earth had the bug been eating before synthetic chlorinated compounds were invented some 50 years ago?

Sequencing of the Strain 195 genome at the Institute for Genomic Research (TIGR), Rockville, Md., which is reported in the latest issue of the journal Science (Jan. 7, 2005), helps resolve the second question. An up-and-coming bioremediation industry, based on Strain 195, answers the first.

"Strain 195 has a relatively small genome, only about a third the size of E. coli's in base pairs, but it's a highly adaptable one with clusters of genes called mobile genetic elements," says Cornell professor of microbiology Stephen H. Zinder. He named and studied Strain 195 after James M. Gossett, Cornell professor of civil and environmental engineering, found the enterprising organism in sewage sludge.

"Just by picking up these mobile genetic elements from other bacteria, Dehalococcoides strains seem able to adapt and to take advantage of opportunities as they present themselves," Zinder notes.

The genomic analysis showed how various Dehalococcoides strains are able to make enzymes called reductive dehalogenases to dechlorinate chlorobenzenes, chloronapthalenes, polychlorinated biphenyls and dibenzodioxins -- by turning the genes on and off as the organism detects something appetizing. Since Strain 195 requires diverse nutrient
'"/>

Contact: Bill Steele
ws21@cornell.edu
607-255-7164
Cornell University News Service
6-Jan-2005


Page: 1 2 3

Related biology news :

1. New grants bolster efforts to generate faster and cheaper tools for DNA sequencing
2. Back to the future: Mastodon extends the time limit on DNA sequencing
3. Liverpool amongst first in UK to install unique DNA sequencing technology
4. Discovery could help bring down price of DNA sequencing
5. 454 sequencing identifies HIV drug resistance at early stage
6. Ultra deep sequencing identifies HIV drug resistance at early stage
7. 454 Life Sciences and Baylor College of Medicine complete sequencing of DNA pioneer
8. LSU professor involved in genome sequencing of the first marsupial
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. Gene sequencing advance will aid in biomass-to-biofuels conversion
11. Genome sequencing reveals key to viable ethanol production

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Gene sequencing explains bioremediation bug

(Date:3/31/2015)... YORK , March 31, 2015   Guidepoint ... the launch of the Post-Surgical Pain Management TRACKER, part ... products tracking usage trends in the medical device and ... access to data including treatment volumes, market share, and ... the pain associated with joint surgery. The ...
(Date:3/24/2015)... and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) has announced ... 2015-2019" report to their offering. The ... at a CAGR of 23.5 percent over the period ... and the growth prospects of the Global Iris Recognition ... size, the report considers the revenue generated from sales ...
(Date:3/24/2015)... , March 24, 2015   Crossmatch ™, ... today announced that its U.are.U ® 4500 ... Goorin Bros . to achieve PCI compliance ... secures access to the POS terminal, protecting the ... of data breaches. With one-third ...
Breaking Biology News(10 mins):Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2
(Date:4/21/2015)... RESEARCH TRIANGLE PARK, N.C. , April 21, 2015 ... announced today that it will release its first quarter ... 28, 2015. United Therapeutics will host a ... a.m. Eastern Time.  The teleconference is accessible by dialing ... the teleconference will be available for one week and ...
(Date:4/21/2015)... Whether it’s used for troubleshooting in a factory, ... Kessler CineDrive in a cinematic studio setting, or ... is designed to help any shooter create vivid high-speed ... the TS5-H offers the same convenient touchscreen controls and streamlined ... According to Tom Boldt for Fastec, “We believe that compelling ...
(Date:4/20/2015)... IL (PRWEB) April 20, 2015 ... of its 12th clinical research site: PMG Research of ... assumed operation of the clinical research department at ... outside the Southeast to a second region within the ... multi-specialty physician practice enhances PMG’s access to an additional ...
(Date:4/20/2015)... , April 20, 2015  Eli Lilly and Company ... from several targeted cancer therapies, reflecting Lilly,s diverse oncology ... Annual Meeting 2015, held April 18-22 in ... Discoveries to Patients" is the theme of this year,s ... commitment to broadening its portfolio of therapies that accelerate ...
Breaking Biology Technology:Fastec Imaging Releases the TS5-H High Definition High-Speed Camera 2Fastec Imaging Releases the TS5-H High Definition High-Speed Camera 3PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 2PMG Research Announces the Formation of its 12th Site in Champaign-Urbana, IL 3Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 2Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 3Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 4Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 5Lilly Releases Early-Stage Pipeline Data at AACR Annual Meeting 2015 6
Cached News: