HOME >> BIOLOGY >> NEWS
Gene therapy for inherited childhood blindness tested in mice

Researchers from Switzerland describe the results in mice of a possible gene therapy treatment for one inherited childhood blindness-a variant of Leber congenital amaurosis-which is caused by mutations in a gene active in the retina, retinal pigment epithelium-specific protein, 65 kDa (RPE65).

Injection of normal Rpe65 into the retina of mice deficient in Rpe65 led to expression of the protein product of Rpe65 in the retina. Electrical recordings of the activity of the eyes in these mice showed that the treatment restored retinal function to near-normal levels and prevented degeneration in one type of retinal cell-the cones-until at least four months, an age at which almost all cones have degenerated in untreated Rpe65-deficient mice.


'"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
9-Oct-2006


Page: 1

Related biology news :

1. Testosterone replacement therapy: How safe for aging men?
2. Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
3. Aggressive therapy best for certain AML patients
4. Under magnetic force, nanoparticles may deliver gene therapy
5. 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
6. Stem cell therapy rescues motor neurons in ALS model
7. Study identifies new gene therapy tools for inherited blindness
8. Breast cancer and hormone therapy -- A looking-glass mirror?
9. Radiation therapy combined with microsurgery shows promise for curing injured spinal cord
10. Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
11. Scientists follow familiar TRAIL to new cancer therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... Vigilant Solutions announces today that an agency used its Vigilant ... in a difficult homicide case. The agency then used Vigilant,s ... vehicle. Due to the ongoing investigation, the agency name and ... agency,s request. --> --> ... deceased at an intersection here in the City. He had ...
(Date:2/4/2016)... -- The field of Human Microbiome research and ... hubs of the biotechnology industry. While the Human ... human microbiota, have garnered a lot of attention ... has literally exploded in terms of both basic ... on biomedical aspects of research, development, and commercial ...
(Date:2/3/2016)... Calif. , Feb. 3, 2016 Vigilant ... Police Department in Missouri ... license plate reader (LPR) data from Vigilant Solutions. ... hit-and-run case in which the victim was walking out of a convenience ... parking space next to his vehicle, striking his vehicle ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... NY (PRWEB) , ... February 10, 2016 , ... LATHAM, ... packages at the SPIE Photonics West conference in San Francisco’s Moscone Center ... 14 in the same venue. , These latest InGaAs PIN diode standard packages ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... medicine, has announced a new agreement with Singapore-based Global Stem Cells Network (GSCN) ... the Philippines, Thailand and Singapore in the latest adipose and bone marrow therapies. ...
(Date:2/9/2016)... N.J. , Feb. 9, 2016  Regenicin, ... biotechnology company specializing in the development and commercialization ... of damaged tissues and organs, recently reported the ... the first quarter of 2016. Lonza ... the new 2015 fiscal year in the process ...
(Date:2/9/2016)... ... , ... Tunnell Consulting, Inc. announced that Frédéric Lefebvre has joined the firm ... new accounts and work closely with existing Tunnell clients throughout Europe to ensure their ... clients more than 15 years of experience in the pharmaceutical industry, a thorough knowledge ...
Breaking Biology Technology:
Cached News: