HOME >> BIOLOGY >> NEWS
Genetic data crunching achieves milestone at Stanford

STANFORD, Calif. - The revolution was not televised.

In the fall of 1999, the Stanford Microarray Database booted up, and a level of computing power was suddenly available to the field of molecular biology that only a few years earlier was inconceivable. On Oct. 19, the database recorded its 50,000th experiment, marking its place at the forefront of an information processing revolution that has yielded groundbreaking insights into the relationships between genes and illness, as well as fundamental biological discoveries.

Microarrays, developed in the lab of biochemistry professor Patrick Brown, MD, PhD, in the early 1990s, took molecular biology by storm. They're small slides spotted with fixed samples of DNA, each for a different gene. When a researcher prepares a labeled cell extract and incubates it with the slide, messengers in the sample stick to the fixed DNA, showing which genes in the sample are active. Microarrays are especially useful for comparisons between normal and cancerous tissues or between different stages of development. Researchers use them to nose out the genes associated with such changes.

The problem, however, is that experiments with microarrays yield vast amounts of data. "Microarrays allow researchers to do in six months what previously would have taken six years of concerted effort," explained Gavin Sherlock, PhD, assistant research professor in genetics, who has been involved in the Stanford database from the beginning.

The need for the university database became apparent in the late 1990s after Brown and David Botstein, PhD, former chair of the genetics department, had put together a database for their own microarray results. They soon found that they needed something more sophisticated. Efficient processing and storing of microarray data, as well as the ability to easily retrieve and compare data with other experiments were all required. New information about genes spotted on the slides is continuously di
'"/>


20-Oct-2004


Page: 1 2 3

Related biology news :

1. Genetic variation helps to understand predisposition to schizophrenia
2. Genetic factors strongly shape how peers are chosen
3. Genetic analysis finds greater threat in frog-killing fungus
4. Genetic diversity in honeybee colonies boosts productivity
5. 2007-2008 Genzyme/ACMGF Clinical Genetics Fellowship In Biochemical Genetics award winner announced
6. Maynard Olson receives $500,000 Gruber Genetics Prize
7. Genetic defect links respiratory disease and congenital heart disease
8. Cell Press announces new partnership with the American Society of Human Genetics
9. Genetic fellow traveler discovered in Alzheimers
10. Genetic roots of bipolar disorder revealed by first genome-wide study of illness
11. Health disparities -- Genetics, society and race play an important role in access to healthcare

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/9/2019)... (PRWEB) , ... March 07, 2019 , ... A firm ... to The Leukemia & Lymphoma Society (LLS). This donation will help fund not only ... patients and their families. , “We are always on the lookout for ways ...
(Date:3/9/2019)... ... March 09, 2019 , ... ... hM4Di ligands – exciting compounds for scientists studying GPCR and DREADD signalling. Hello ... and the National Institute of Neurological Disorders and Stroke, both institutes of the ...
(Date:2/27/2019)... ... 2019 , ... Fluxion Biosciences, a leading developer of precision solutions for life ... grant for further development of its ERASE-Seq liquid biopsy technology. The Phase I grant ... Dr. Omar Mian at the Cleveland Clinic. , Liquid biopsies offer the potential to ...
Breaking Biology News(10 mins):
(Date:3/14/2019)... ... March 14, 2019 , ... ... solution for preclinical research organizations. It is a low code, GDPR/21 CFR ... and facilities, innovative technology-driven automated data capture and seamless data and information ...
(Date:3/11/2019)... ... , ... USDM Life Sciences and Generis have partnered ... GxP compliance for the life sciences industry. USDM Cloud Assurance delivers a ... for Generis’ flagship product, CARA. , Presentation One:, What: Cloud ...
(Date:3/5/2019)... ... March 05, 2019 , ... Modality Solutions, ... with regulatory filing authorities, logistics network experts, and experienced integrated staffing professionals. ... in the Inc. Verified Profile program, Inc. editors independently reviewed the Houston-based cold ...
(Date:2/26/2019)... ... February 26, 2019 , ... The idea for ... Villani developed the Visikol® tissue clearing technology for improved tissue characterization. From this ... products focused company to primarily a services focused company. , Today, Visikol ...
Breaking Biology Technology:
Cached News: