Genome of ancient fish could reveal evolutionary mysteries, Stanford scie...( be at issue. Where most fish reproduce ...)

Genome of ancient fish could reveal evolutionary mysteries, Stanford scientists say

be at issue. Where most fish reproduce quickly and have short generation times, the coelacanth reproduces slowly and gives birth to live young. This means that the coelacanth has had fewer generations of offspring to accumulate mutations.

The fact that coelacanth is available for sequencing is a lucky accident. They were thought to be extinct until 1938 when museum curator Marjorie Courtaney-Latimer discovered a specimen in a fisherman's catch near Cape Town, South Africa. In 1998 a honeymooning researcher found a second population off the coast of Indonesia.

Last year Myers and David Kingsley, PhD, professor of developmental biology, successfully recommended that a fish called the stickleback be added to the list of organisms to be sequenced by the National Human Genome Research Institute at the NIH. Myers said he, Noonan and other researchers who contributed to the article in Genome Research will be submitting the coelacanth for consideration soon.

Other Stanford researchers at the Stanford Human Genome Center who contributed to this work include Jane Grimswood, finishing group leader; Jeremy Schmutz, informatics group leader, and Mark Dickson, production sequence group leader.

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Contact: Amy Adams
amyadams@stanford.edu
650-723-3900
Stanford University Medical Center
16-Nov-2004

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