HOME >> BIOLOGY >> NEWS
Genomics study provides insight into the evolution of unique human traits

AURORA, Colo. (Tues., July 31, 2007) Today, researchers from the University of Colorado Health Sciences Center, along with colleagues from Stanford University, report the results of a large-scale, genome-wide study to investigate gene copy number differences among ten primate species, including humans. The study provides an overview of genes and gene families that have undergone major copy number expansions and contractions in different primate lineages spanning approximately 60 million years of evolutionary time. In the report, which appears online in Genome Research (www.genome.org), the scientists speculate how unique, lineage-specific gene copy number expansions and contractions in humans may underlie traits such as endurance running, higher cognitive function, and susceptibility genetic disease.

Primates first appeared on earth approximately 90 million years ago, and today, about 300 different species of primates exist. One of the main genomic driving forces in primate evolution is gene duplication, explains Dr. James Sikela, Professor at the University of Colorado. To our knowledge, this study is the most comprehensive assessment of gene copy number variation across human and non-human primate species so far.

To survey the differences in gene copy number among these species, Sikela and colleagues used DNA microarrays containing over 24,000 human genes to perform comparative genomic hybridization experiments. They compared DNA samples from humans to those of nine other primate species: chimpanzee, gorilla, bonobo, orangutan, gibbon, macaque, baboon, marmoset, and lemur. This allowed them to identify specific genes and gene families that, through evolutionary time, have undergone lineage-specific copy number gains and losses.

The authors of the report suggest that many of the genes identified are likely to be important to lineage-specific traits found in humans and in the
'"/>

Contact: Maria Smit
smit@cshl.edu
516-422-4127
Cold Spring Harbor Laboratory
30-Jul-2007


Page: 1 2

Related biology news :

1. Psychiatric Genomics Center established at Cold Spring Harbor Laboratory
2. NYUs Center for Comparative Functional Genomics part of $57 million MOD-ENCODE consortium
3. Elsevier launches new journal, Marine Genomics
4. Genomics throws species definition in question for microbes
5. International Genomics Consortium, TGen to lead Biospecimen Core for Cancer Atlas pilot project
6. DOE JGI to host Microbial Genomics Workshop for educators
7. Genomics-based vaccine could prevent deadly cattle disease
8. Genomics reveals mechanism of heat resistance in bacteria
9. NYUs Center for Comparative Functional Genomics helps to unravel the function of microRNAS
10. Genomics champion Eric Lander receives 2004 AAAS Public Understanding of Science & Technology Award
11. International Rice Functional Genomics meeting in Tucson Nov. 15-17

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/7/2018)... ... November 07, 2018 , ... John Powers, co-founder ... business incubator, is pleased to announce that Gene Tox Lab Solutions, LLC has ... solutions to help healthcare organizations including hospitals and clinics manage their patient population ...
(Date:11/7/2018)... ... November 07, 2018 , ... Features such as 24/7 ... last-minute changes all contribute to client retention and referral business in the clinical ... expense services provider says 80 percent of its new business is attributed to ...
(Date:11/7/2018)... BOSTON, Mass. (PRWEB) , ... November 07, 2018 ... ... cloud-based enterprise-class unified communications and collaboration solutions, announced today a modernized and streamlined ... label exclusive website and a newly established reseller administrative control portal. CallTower ...
Breaking Biology News(10 mins):
(Date:11/11/2018)... DIEGO (PRWEB) , ... November 09, 2018 , ... Triple ... a CES® 2019 Innovation Awards Honoree for DFree ®, the first ... notifies you when it’s time to go to the bathroom. The announcement was made ...
(Date:11/7/2018)... ... ... Diversified Technologies, Inc. (DTI) has installed a PEF (Pulsed Electric ... and Innovation at ASU. Funded by a USDA NIFA SBIR, the purpose of the ... predator control applications. , Algae ponds get up to 50% consumed by predators and ...
(Date:11/5/2018)... ... November 05, 2018 , ... ... 2Blades’ Transcription Activator Like (TAL) effector code technology for applications in advancing research ... the technology in plants. Since its discovery in 2009, the efficacy of TAL effector-based ...
(Date:10/31/2018)... ... October 30, 2018 , ... Pippa Rose is a young Labrador retriever. Like most labs, ... suffered a partial tear to the cruciate ligament in her right knee. According to ... walks. Kinsley reported that it broke her heart to see Pippa lie around in ...
Breaking Biology Technology:
Cached News: