HOME >> BIOLOGY >> NEWS
Getting on your nerves ... and repairing them

BETHESDA, MD Here is some news that will certainly get on people's nerves: In a study to be published in the March 2007 issue of The FASEB Journal, scientists from East Carolina University report that a key molecular mechanism, RNA interference (RNAi), plays a role in the regeneration and repair of periphery nerves, which are the nerves located outside of the brain and spinal column. This research may lead to new therapies that manipulate RNAi to treat people with damaged nerves resulting from degenerative disorders and injury.

Andrew Z. Fire of Stanford University and Craig C. Mello of the University of Massachusetts won the 2006 Nobel Prize for the discovery of RNAi. This study builds on this and other RNAi research, which was reviewed in the July 2006 issue of The FASEB Journal, showing that RNAi regulates the creation of proteins in the body. Until now, there has been no direct evidence that RNAi controls local protein synthesis in axonal nerve fibers, which act as "pavement" for the nervous system's "information superhighway." In addition, the mechanism involved in the nerve fiber creation did not depend on communication with, or transport from, the nerve cell body or its nucleus, or from surrounding support cells. Axonal nerve fibers can be as long as three feet (sciatic nerve), and this independence makes RNAi a promising drug target.

"Repairing and rebuilding damaged nerve tissue is one of the greatest medical advances not yet achieved," said Gerald Weissmann, MD, Editor-in-Chief of The FASEB Journal, "and this research is a huge leap forward. It's no accident that a Nobel Prize discovery should be followed up by great new science."


'"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
15-Feb-2007


Page: 1

Related biology news :

1. Getting to the root of plant growth
2. Getting to the core of an emergent public health threat
3. Getting dirty may lift your mood
4. Getting ones protein in a bunch -- When quality control fails in cells
5. Getting to the bottom of memory
6. Getting to the heart of the heart
7. Getting America really ready
8. Getting ahead of cancer: SPECT/Spiral CT technology enhances bone scanning, earlier diagnosis
9. Getting ACL tears to heal themselves
10. Getting an evolutionary handle on life after reproduction
11. Getting old? Slowing down? Blame inefficient mitochondria

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... ... , ... Regenative Labs has received approval from the Centers for Medicare & ... first Wharton’s jelly allografts to be assigned a Q code and be approved for ... Wharton’s jelly allograft product to be recognized as a 361 HCT/P by CMS regulated ...
(Date:7/18/2020)... ... July 16, 2020 , ... A study has been published ... Neoasis™ active noise control device to attenuate typical noises in a simulated neonatal ... the alarm sounds from patient monitors, ventilators and other bedside devices that would ...
(Date:7/2/2020)... ... July 01, 2020 , ... AltruBio Inc. http://www.altrubio.com ... a biologic for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD), at European ... J Martin of the Fred Hutchinson Cancer Research Center, this single-arm, open-label Phase ...
Breaking Biology News(10 mins):
(Date:8/12/2020)... FARMS, Mich. (PRWEB) , ... August 12, 2020 ... ... Consulting Group, Inc. (EMMA International), a global leader in FDA compliance consulting ... of the nation’s fastest-growing private companies. The list represents a unique look at ...
(Date:8/3/2020)... (PRWEB) , ... August 03, 2020 , ... ... collection, today announced Jim Corrigan, President and CEO has been named one of ... broad cross-section of industry sectors, PharmaVoice 100 honorees are selected based on how ...
(Date:7/31/2020)... ... July 29, 2020 , ... R3 Stem Cell International is ... $3950. With 50 million stem cells total, patients may choose which extremities they would ... for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, umbilical cord tissue is ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... transmitter systems that can be configured to drive Klystrons, TWTs, IOTs, and magnetrons. ... drive one or two switches in a push-pull configuration; yielding fast fall time ...
Breaking Biology Technology:
Cached News: