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Glucose triggers brain cell death in rats after hypoglycemic coma

ed."

Swanson adds two strong cautions, however: "First, the work was done in rodents, and it is not legitimate to immediately extrapolate these findings to humans. Second, there are many ways to go wrong in humans by not treating hypoglycemia aggressively enough. The results of this one paper do not mean that clinicians should take an overly cautious approach to hypoglycemic coma."

In his own current research, Swanson is investigating the possible roles of glucose and NADPH oxidase as agents of oxidative stress in a rodent model of ischemic stroke. "So far, the results are very promising," he says.


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Contact: Steve Tokar
steve.tokar@ncire.org
415-221-4810 x5202
University of California - San Francisco
4-Apr-2007


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