HOME >> BIOLOGY >> NEWS
Gold nanoparticles prove to be hot stuff

Gold nanoparticles are highly efficient and sensitive "handles" for biological molecules being manipulated and tracked by lasers, but they also can heat up fast--by tens of degrees in just a few nanoseconds--which could either damage the molecules or help study them, according to scientists at JILA, a joint institute of the National Institute of Standards and Technology (NIST) and University of Colorado at Boulder.

Biophysicists often study nanoscale and even picoscale mechanics by using lasers to both apply force to and track the position of fragile biomolecules such as DNA or protein by manipulating a tiny sphere--typically polystyrene--attached to the molecule. The JILA team would like to find new microsphere materials that can be trapped by laser radiation pressure more efficiently, which would enable faster measurements and detection of smaller motions at the same laser power. As described in the Aug. 15 issue of Optics Letters,* the JILA team demonstrated that 100-nanometer-wide gold beads, as expected because of their metallic nature, can be trapped and detected six times more easily than polystyrene particles of a similar size.

However, the scientists also found that gold absorbs light and heats up quickly, by a remarkable 266 degrees (Celsius) per watt of laser power, at the wavelength most often used in optical traps. Unless very low laser power is used, the heat could damage the molecules under study. Thus, gold beads would not be useful for temperature-sensitive experiments or applying force to molecules. But the heating effect could be useful in raising local temperatures in certain experiments, such as heating a protein just enough to allow scientists to watch it unfold, the paper suggests.


'"/>

Contact: Laura Ost
laura.ost@nist.gov
301-975-4034
National Institute of Standards and Technology (NIST)
31-Aug-2006


Page: 1

Related biology news :

1. Gold nanoparticles may pan out as tool for cancer diagnosis
2. Under magnetic force, nanoparticles may deliver gene therapy
3. UCSB researchers show how to make polymeric micro- and nanoparticles
4. Pairing nanoparticles with proteins
5. In nature, proteins sweep up nanoparticles
6. Bacteria ferry nanoparticles into cells for early diagnosis, treatment
7. MU researchers examine the environmental effects of silver nanoparticles
8. Work with nanoparticles may lead to on-the-spot virus detector
9. Widely used iron nanoparticles exhibit toxic effects on neuronal cells
10. Test finds manufactured nanoparticles dont harm soil ecology
11. DNA nanoparticles hold promise in gene therapy for Parkinsons disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/2/2016)... The Weather Company , an IBM Business (NYSE: IBM ... which consumers will be able to interact with IBM Watson ... or text and receive relevant information about the product or ... long sought an advertising solution that can create a one-to-one ... valuable; and can scale across millions of interactions and touchpoints. ...
(Date:5/20/2016)... MINNEAPOLIS , May 20, 2016  VoiceIt ... technology partnership with VoicePass. By working ... user experience.  Because VoiceIt and VoicePass take slightly ... two engines increases both security and usability. ... expressed excitement about this new partnership. ...
(Date:5/3/2016)... 2016  Neurotechnology, a provider of high-precision biometric ... Biometric Identification System (ABIS) , a complete system ... ABIS can process multiple complex biometric transactions with ... fingerprint, face or iris biometrics. It leverages the ... MegaMatcher Accelerator , which have been used ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 /PRNewswire/ - FACIT ... Ontario biotechnology company, Propellon Therapeutics ... development and commercialization of a portfolio of first-in-class ... Epigenetic targets such as WDR5 represent an exciting ... significantly in precision medicine for cancer patients. Substantial ...
(Date:6/23/2016)... SANTA MONICA, Calif. , June 23, 2016  The Prostate Cancer ... to pioneer increasingly precise treatments and faster cures for prostate cancer. Members of ... 77 institutions across 15 countries. Read More About the ... ... ...
(Date:6/23/2016)... ... , ... STACS DNA Inc., the sample tracking software company, today announced that ... joined STACS DNA as a Field Application Specialist. , “I am thrilled that ... of STACS DNA. “In further expanding our capacity as a scientific integrator, Hays brings ...
(Date:6/23/2016)... Andrew D Zelenetz ... Published recently in Oncology ... touchONCOLOGY, Andrew D Zelenetz , discusses the ... is placing an increasing burden on healthcare systems ... With the patents on many biologics expiring, interest ...
Breaking Biology Technology:
Cached News: