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Green tea polyphenols thwart prostate cancer development at multiple levels

mouse model. The reduction of VEGF may result from GTP-induced suppression of IGF-1 levels. VEGF functions to recruit and develop new blood vessels that carry nutrients to developing tumors. By reducing the amount of VEGF, GTP works to minimize nutrients flowing to and supporting tumor growth.

Mukhtar's colleagues contributing to the study included Vaqar Mustafa Adhami, Imtiaz Ahmad Siddiqui, and Nihal Ahmad from the University of Wisconsin; and Sanjay Gupta from Case Western Reserve University.


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Contact: Russell Vanderboom
vanderboom@aacr.org
215-440-9300
American Association for Cancer Research
1-Dec-2004


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