HOME >> BIOLOGY >> NEWS
Growing lymph vessels with macrophages? Surprisingly, yes!

When the cornea is inflamed, blood and lymphatic vessels grow into it. But the cornea is typically an avascular area. In a new study appearing in the September 1 print issue of The Journal of Clinical Investigation, Joan Streilein and colleagues from the Schepens Eye Institute examine which cells generate these new lymphatic vessels in the cornea. The authors find that innate immune cells, in particular macrophages, contribute to this vessel formation during abnormal corneal conditions, and that bone marrow derived macrophages express lymphatic markers under conditions of corneal inflammation. These findings suggest a new mechanism of the formation of lymph vessels, where macrophages are responsible during inflammation.

In a related commentary, Dontscho Kerjaschki writes, "these findings add yet another facet to the plasticity of macrophages, which are already known to transform from nave monocytes into VEGF-producing cells. Thus, macrophages support lymphangiogenesis in 2 different ways, either by transdifferentiating and directly incorporating into the endothelial layer or by stimulating division of preexistent local lymphatic endothelial cells."


'"/>

Contact: Stacie Bloom
press_releases@the-jci.org
212-342-4159
Journal of Clinical Investigation
1-Sep-2005


Page: 1

Related biology news :

1. Growing nerve cells in 3-D dramatically affects gene expression
2. Growing evidence of sex-based differences in lung cancer highlighted at roundtable meeting
3. Growing cities in arid regions
4. Sentinel lymph node biopsy is associated with breast cancer rates
5. Migration alert -- How tumor cells home in on the lymphatic system
6. Novel test identifies lymphoma patients likely to respond to new therapy
7. New hope for patients with chronic lymphocytic leukemia
8. Researchers identify cells that make relapse inevitable in acute lymphoblastic leukemia
9. Antibiotic treats lymphoma of the eye
10. Targeting wolbachia, doxycycline reduces pathology of lymphatic filariasis
11. UC Davis researchers report new molecule that targets leukemia and lymphoma cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/4/2019)... , ... June 04, 2019 , ... ... of orthopedic medical devices, today announced Q1-19 revenues of $31M, up 12% from ... with successful roll-out of strategic investments & operational excellence initiatives worldwide. , ...
(Date:6/4/2019)... ... ... Lajollacooks4u is delighted to announce it has been named as one of ... only to businesses that have achieved consistently outstanding traveler reviews on TripAdvisor, as well ... qualify for the Certificate of Excellence –- an award that only 10 percent of ...
(Date:5/31/2019)... , ... May 30, 2019 , ... ... testing company, and Mayo Clinic, have documented significant differences in the prevalence of ... and ethnic populations compared to non-Hispanic White women. Results will be presented at ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 30, 2019 , ... A study ... efficient delivery system for the sustained release of human placental stem cell (HPSC)-derived ... was able to deliver CM into the injured kidney, where it helped restore ...
(Date:5/15/2019)... ... 15, 2019 , ... Milton Hershey School® has named William Charles Ballough Harding ... biomedical industry, where he is changing lives by creating solutions to global healthcare challenges ... the vision of our founders – Milton and Catherine Hershey – who always hoped ...
(Date:5/14/2019)... LA JOLLA, Calif. (PRWEB) , ... May 14, 2019 , ... ... announces an office expansion, effectively doubling its space from 2,500 to 5,000 square feet. ... SneakPeek Early Gender DNA tests ,” says Gateway Genomics CEO, Chris Jacob. “The ...
(Date:5/4/2019)... Brazil (PRWEB) , ... May 03, 2019 , ... ... given by the President of the Dakila Pesquisas Association, the scientist and ufologist ... Councilmen 2019, in Brasília (DF). Urandir detailed the results of some research carried ...
Breaking Biology Technology:
Cached News: