HOME >> BIOLOGY >> NEWS
Heart has enough oxygen to survive hypothermia, CPR crucial

ic groups and a control group. They exposed one hypothermic group to 15C (59F) for one hour before rewarming. They exposed the second group to 15C, but for five hours. The control group was kept at normal temperature, 37C (98.6F). The researchers followed the hemodynamic changes during hypothermia and rewarming and later examined the rats' heart cells.

When core body temperature was lowered to 15C, both hypothermic groups experienced a similar reduction in circulating blood volume. And both showed that the physiological mechanisms that help transport oxygen and help unload oxygen from hemoglobin were working. "As a consequence, oxygen supply was not a limiting factor for survival in the present experiments," the authors wrote.

The rats in the one-hour group spontaneously normalized their blood pressure, cardiac output and heart rate after they were rewarmed, Tveita noted. However, the rats in the five-hour group, which were significantly more likely to experience heart failure during rewarming, experienced substantial lowering of cardiac output and other cardiac functions.

"We conclude that the heart failure we see after rewarming is not due to a lack of oxygen supply or oxygen transportation because unloading of oxygen at the cell level from hemoglobin is functioning," Tveita stated. Thus, it appears that the problem comes as a result of the lower cardiac output, he added.

"Thus, efforts aimed at elevating cardiac output in this phase seem advisable in order to optimize oxygen supply, reperfuse (restore blood flow to) vascular beds (minute blood vessels) and prevent rewarming shock formation," the authors wrote

Source and funding

"Is oxygen supply a limiting factor for survival during rewarming from profound hypothermia?" by Timofei V. Kondratiev, Kristina Flemming, and Mikhail A. Sovershaev, University of Troms, Norway; Eivind S.P. Myhre, Srlandet Hospital, Kristiansand; and Torkjel Tveita, Univer
'"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
18-Jul-2006


Page: 1 2 3 4

Related biology news :

1. Hearts of male and female rainbow trout are different
2. Heart failure: Intervention possibilities from imaging programmed cell loss
3. Heart intervention doesnt outweigh medicine in study
4. International Society for Heart and Lung Transplantation 27th Annual Meeting and Scientific Sessions
5. Heart rhythm genes possible factors in SIDS
6. Hearts or tails?
7. Heart smart: new drug improves blood flow
8. Defusing a time bomb: Heart attack risk-detection technology developed at UH
9. Heart failure wall stress drops 38% with moderate thyroid hormone therapy
10. New studies released at the Heart Rhythm Societys Annual Meeting
11. Molecular testing impact: Heart transplant patients benefit from new technology, easier monitoring

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/29/2017)... the health IT company that operates the largest health ... today announced a Series B investment from BlueCross BlueShield ... investment and acquisition accelerates higi,s strategy to create the ... activities through the collection and workflow integration of ambient ... secures data today on behalf of over 36 million ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
(Date:3/24/2017)... , Mar 24, 2017 Research and Markets ... System Market Analysis & Trends - Industry Forecast to 2025" ... ... grow at a CAGR of around 15.1% over the next decade ... industry report analyzes the market estimates and forecasts for all the ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Vortex Biosciences , ... “Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology ” in Nature ... a collaboration with Dr. Dino Di Carlo and Dr. Matthew Rettig at the University ...
(Date:5/23/2017)... , ... May 23, 2017 , ... Bacterial biofilms, surface ... molecules, can cause diverse pathologies ranging from food poisoning and catheter infections to gum ... is in the tens of billions of dollars per year, there is currently a ...
(Date:5/22/2017)... ... May 22, 2017 , ... Stratevi, a boutique firm that partners ... Coast. It has opened an office in downtown Boston at 745 Atlantic Ave. ... more important to generate evidence on the value they provide, not just to patients, ...
(Date:5/21/2017)... ... May 19, 2017 , ... Ovation Fertility scientists’ work is ... of Bioanalysts (AAB) and the College of Reproductive Biology (CRB) today and Saturday ... to excellence in clinical laboratory services and regulations. , “We are pleased ...
Breaking Biology Technology:
Cached News: