HOME >> BIOLOGY >> NEWS
Heart rhythm genes possible factors in SIDS

Nearly 10 percent of sudden infant death syndrome (SIDS) victims have mutations or variations in genes associated with potentially lethal heart rhythms (arrhythmias), according to two newly published studies involving Vanderbilt researchers.

The findings indicate that arrhythmia-susceptibility genes represent important genetic contributors to SIDS, said Alfred L. George Jr., M.D., senior author on one of the studies. The studies appear in the early online edition of the journal Circulation.

According to the Centers for Disease Control and Prevention, approximately 2,200 deaths each year in the United States are attributed to SIDS, making it the third leading cause of death among all infants, but the leading cause of mortality in infants age 1 month to 1 year. Several behavioral and environmental factors such as prone (stomach) sleeping position and exposure to cigarette smoke are known risk factors. Campaigns to educate parents about these potential dangers may explain the decrease in SIDS since the early 1990s.

However, SIDS continues to be a leading cause of infant mortality in developed countries, and the underlying basis of the condition remains unclear. A popular theory proposes that SIDS occurs because of a combination of risks including abnormal physiological state, environmental factors and developmental vulnerabilities. Genetic factors have also been proposed to be important.

"SIDS is not one disease," said George, the Grant W. Liddle Professor of Medicine and director of the Division of Genetic Medicine. "Multiple conditions can increase the risk of sudden death in an infant. Some have been identified, but many have not."

Anecdotal evidence previously suggested that some SIDS victims carry mutations in genes associated with conditions such as the long QT syndrome (LQTS) that predispose individuals to life-threatening arrhythmias and sudden death. But the proportion of SIDS cases that carry such mutat
'"/>

Contact: Craig Boerner
craig.boerner@Vanderbilt.Edu
615-322-4747
Vanderbilt University Medical Center
16-Jan-2007


Page: 1 2 3

Related biology news :

1. Hearts of male and female rainbow trout are different
2. Heart failure: Intervention possibilities from imaging programmed cell loss
3. Heart intervention doesnt outweigh medicine in study
4. International Society for Heart and Lung Transplantation 27th Annual Meeting and Scientific Sessions
5. Hearts or tails?
6. Heart smart: new drug improves blood flow
7. Heart has enough oxygen to survive hypothermia, CPR crucial
8. Defusing a time bomb: Heart attack risk-detection technology developed at UH
9. Heart failure wall stress drops 38% with moderate thyroid hormone therapy
10. New studies released at the Heart Rhythm Societys Annual Meeting
11. Molecular testing impact: Heart transplant patients benefit from new technology, easier monitoring

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2020)... , ... August 19, 2020 , ... ... LLC and SalivaBio LLC, businesses dedicated to Salivary Bioscience for more than twenty ... recently published book by Springer, " Salivary Bioscience: Foundations of Interdisciplinary Saliva Research ...
(Date:8/21/2020)... ... August 20, 2020 , ... ... Hassan Movahhed , a Clinical Operations executive with expertise in clinical trial planning ... the firm as an Expert Consultant. Throughout his career, Mr. Movahhed has helped ...
(Date:8/12/2020)... ... August 12, 2020 , ... Mosio recently announced ... for public health agencies of all sizes. With a focus on tracking symptoms ... find appropriate health care, Mosio helps public health departments automate communications and provide ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine today revealed ... prestigious ranking of the nation’s fastest-growing private companies. The list represents a unique ... independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many other well-known ...
(Date:8/12/2020)... ... August 11, 2020 , ... ... making available for free its new white paper – Simulated Transport Methodologies. ... into today’s biologics licensing application (BLA). In response, Modality Solutions shares an ...
(Date:8/7/2020)... ... 06, 2020 , ... VGXI, a highly regarded CDMO supporting ... purchase of greenfield for a new, expanded manufacturing facility. The site is located ... the initial acquisition, with an option to purchase an additional 21 acres for ...
(Date:8/3/2020)... ... ... Introducing Ardent Animal Health – MediVet Biologics rebrands company and positions its platform ... Biologics since its formation in 2016, the company is relaunching itself under the Ardent ... its base of innovative therapies for osteoarthritis and cancer. , ...
Breaking Biology Technology:
Cached News: