Hearts of male and female rainbow trout are different

Ventricle rings were processed, sectioned and stained. Light microscopy was used to capture images of ventricle layers and analyzed for layer cross-sectional areas. Lactate concentration and net lactate release from cardiac tissue was also examined.


The researchers found:

  • ventricle strips from males and females had similar rates of oxygen consumption and lactate release under resting conditions;

  • the inhibition of oxidative metabolism with NaCN lowered cardiac performance dramatically, and elevated resting tension and lactate release in both males and females;

  • under stimulated conditions with DCA vs. controls, female ventricle strips selectively demonstrated better performance and reduced lactate release;

  • force production during reoxygenation -- after a hypoxic insult -- significantly improved in males receiving DCA, but not females;

  • male ventricle tissue had 2.5-fold higher citrate concentrations than females; and;

  • males had a proportionately larger epicardium to endocardium ratio compared with females with similar size hearts.

Summary and Conclusions

This study expands upon previous findings that sex differences in cardiac performance and metabolism exist in fish in general, and have now been found to occur in rainbow trout in particular. Moreover, the differences are only realized during working conditions and involve stimulation or inhibition of the glycolytic pathway and carbohydrate oxidation. Ultimately, sex differences in cardiac energy metabolism and function may help define habitat suitability, swimming capabilities and health status of wild and hatchery-reared rainbow trout, and human heart disease, sex-specific treatment.


Contact: Donna Krupa
American Physiological Society

Page: 1 2 3

Related biology news :

1. Hearts or tails?
2. Cardio exercise benefits in male vs. female hearts
3. The female advantage in kidney disease does not extend to diabetic women
4. Disabling a sensory organ prompts female mice to act like male mice
5. A sensory organ, not the brain, differentiates male and female behavior in some mammals
6. MGH researchers confirm that bone marrow restores fertility in female mice
7. Male or female factor infertility -- men suffer just the same
8. CU study reveals why starling females cheat
9. Philandering female felines forgo fidelity
10. Update on census of wrlds most endangered cat -- female Amur leopard found dead
11. The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better

Post Your Comments:

(Date:11/18/2015)... Nov. 18, 2015  As new scientific discoveries deepen ... and other healthcare providers face challenges in better using ... patients. In addition, as more children continue to survive ... adulthood and old age. John M. Maris, ... Hospital of Philadelphia (CHOP) . --> ...
(Date:11/17/2015)... , Nov. 17, 2015 Pressure BioSciences, Inc. ... the development and sale of broadly enabling, pressure cycling ... sciences industry, today announced it has received gross proceeds ... million Private Placement (the "Offering"), increasing the total amount ... or more additional closings are expected in the near ...
(Date:11/11/2015)... MedNet Solutions , an innovative SaaS-based eClinical technology company that ... announce that it will be a Sponsor of the ... held November 17-19 in Hamburg , Germany.  ... iMedNet , MedNet,s easy-to-use, proven and affordable eClinical ... able to deliver time and cost savings of up to ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015 /PRNewswire/ - Aeterna Zentaris ... that its business and prospects remain fundamentally strong ... Zoptrex™ (zoptarelin doxorubicin) recently received DSMB recommendation to ... completion following review of the final interim efficacy ... 2 Primary Endpoint in men with heavily pretreated ...
(Date:11/25/2015)... CA (PRWEB) , ... November 25, 2015 , ... ... genomics company uBiome, were featured on AngelList early in their initial angel funding ... an AngelList syndicate for individuals looking to make early stage investments in the ...
(Date:11/24/2015)... 2015 Halozyme Therapeutics, Inc. (NASDAQ: HALO ) will ... New York on Wednesday, December 2 at 9:30 a.m. ... and CEO, will provide a corporate overview. th ... at 1:00 p.m. ET/10:00 a.m. PT . Jim Mazzola ... a corporate overview. --> th Annual Oppenheimer Healthcare ...
(Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris ... of IIROC on behalf of the Toronto Stock Exchange, ... release there are no corporate developments that would cause ... --> --> About Aeterna ... www.aezsinc.com . --> Aeterna Zentaris is a ...
Breaking Biology Technology:
Cached News: