HOME >> BIOLOGY >> NEWS
Hot flashes -- Studies explore the role of genes, obesity and alcohol

Many women in the menopausal transition experience hot flashes: unpredictable, sometimes disruptive, periods of intense heat in the upper torso, neck and face. Although generations of physicians have prescribed hormones to reduce these symptoms, very little research has focused on the underlying causes of hot flashes.

Three new studies explore the role of genes, obesity and alcohol consumption in contributing to or lessening the intensity and frequency of hot flashes in midlife women. These studies are part of a five-year research effort led by University of Illinois veterinary biosciences professor Jodi Flaws and colleagues at the University of Maryland, Mercy Medical Center in Baltimore and the School of Medicine at Johns Hopkins University.

Physicians have long noted that some factors, such as smoking, increase the likelihood that a woman will experience more or more intense hot flashes than other women. Race also appears to play a role, with African American women at higher risk than others. But the mechanisms that cause some women to suffer from severe (frequent and intense) hot flashes have remained a mystery.

"Even though more than 40 million women experience hot flashes each year," the authors wrote in their paper published in Maturitas, "little is known about the factors that predispose women to hot flashes."

To examine whether genetics might play a role in hot flashes, Flaws and her colleagues conducted a cross-sectional study involving 639 women aged 45 to 54. The researchers looked at individual differences in the genes that code for various hormones. An earlier study by the same team had found that one of these genetic polymorphisms, in an estrogen metabolizing enzyme, cytochrome P450 1B1, was more common in women who reported higher-than-average frequency, intensity and duration of hot flashes.

The new study tied the same genetic polymorphism to lower levels of an androgen known as DHEA-S, and to
'"/>

Contact: Diana Yates
diya@uiuc.edu
217-333-5802
University of Illinois at Urbana-Champaign
24-Apr-2007


Page: 1 2 3

Related biology news :

1. Studies to find better ways to preserve human eggs, ovarian tissue under way
2. Studies assess effectiveness of serotonin and nerve stimulants on irritable bowel syndromes
3. The Institute of Ecosystem Studies recognized by the Wildlife Society
4. The Institute of Ecosystem Studies to host an international conference on ecology and urban design
5. Studies force new view on biology of flavonoids
6. Studies of population genetics, evolution are an exercise in bad taste
7. Studies identify DNA regions linked to nicotine dependence
8. Studies at cancer conference show new therapies changing outlook for blood cancer patients
9. Studies find general mechanism of cellular aging
10. Institute of Ecosystem Studies director and scientist honored by the Botanical Society of America
11. Studies show that rockfish thrive with offshore platforms as their home base

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... ... August 20, 2019 , ... ... bioactive technologies for the spine, today announced the 510(K) clearance of its novel ... modification that is proven to improve osseointegration through superior hydrophilicity and optimized surface ...
(Date:8/19/2019)... ... August 19, 2019 , ... Since ... use of ultra-thin two dimensional slices which are placed on microscope slides, stained ... complex tissues and complicated features such as vasculature and thus researchers in the ...
(Date:8/15/2019)... , ... August 15, 2019 , ... ... Now what? As serialization mandates become increasingly complex, and aggregation becomes fully applied ... serialization software is the best long-term solution. , Until now, most regulations?including the ...
Breaking Biology News(10 mins):
(Date:6/26/2019)... ... June 26, 2019 , ... Alice Branton today released research results from ... of Magnesium Gluconate, which can prove to be beneficial for treating Hypomagnesemia. , The ... peak, change in crystallite size , Over 142% increase in particle size ...
(Date:6/18/2019)... , ... June 18, 2019 , ... Personalized Stem ... New Drug (IND) application to the FDA for use of a person’s own adipose-derived ... a treatment of osteoarthritis in the knee. This IND is the first of ...
(Date:6/11/2019)... MONTREAL (PRWEB) , ... June 10, 2019 , ... ... growth of its distribution network with the appointment of Biofeedback Tech Ltd ... physiological monitoring systems are an essential part of many therapeutic treatments and clinical ...
(Date:6/11/2019)... ... June 10, 2019 , ... DeepDyve ... its scientific journals to DeepDyve’s rental service for peer-reviewed journals. , IOPP’s ... of more than 20 million articles, sourced from more than 15,000 journals. , ...
Breaking Biology Technology:
Cached News: