HOME >> BIOLOGY >> NEWS
How does a zebrafish grow a new tail?

If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has many different types of cells and is a very intricate structure. It is the fish version of an arm or leg.

The question of how cold-blooded animals re-grow missing tails and other appendages has fascinated veterinary and medical scientists. They also wonder if people, and other warm-blooded animals that evolved from these simpler creatures, might still have untapped regenerative powers hidden in their genes.

People are constantly renewing blood components, skeletal muscles and skin. We can regenerate liver tissue and repair minor injuries to bone, muscle, the tips of our toes and fingers, and the corneas of our eyes. Finding out more about the remarkable ability of amphibians and fish to re-grow complex parts might provide the information necessary to create treatments for people whose hearts, spinal cords, eyes or arms and legs have been badly hurt.

Scientists have discovered some of the genes and cell-to-cell communication pathways that enable zebrafish to restore their tail fins.

"The ability to regenerate body parts such as those that are damaged by injury or disease," said Dr. Randall Moon, professor of pharmacology at the University of Washington (UW), an investigator of the Howard Hughes Medical Institute, and a researcher in the UW Institute for Stem Cell and Regenerative Medicine, "involves creating cells that can take any number of new roles. This can be done by re-programming cells that already have a given function or by activating resident stem cells."

Developmental biologists know that a particular kind of cell-to-cell communication, called Wnt/Beta-catenin signaling, regulates the fate of these as-yet undeveloped cells as an embryo forms. Through a cascade of signals, cells waiting for their calling learn which
'"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
26-Dec-2006


Page: 1 2 3

Related biology news :

1. EPA selects Phylonix to screen compound library in zebrafish
2. Phylonix awarded National Science Foundation Phase II SBIR for zebrafish screening
3. Key to zebrafish heart regeneration uncovered
4. Temperature regulates circadian clock in zebrafish
5. Tiny zebrafish teaches researchers how to fight off a deadly cancer
6. Clues on cancer from a zebrafish model of melanoma
7. Glow-in-the-dark zebrafish at UH hold keys to biological clocks
8. Strawberry daiquiris -- the extra-healthy cocktail?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... GOTHENBURG, Sweden , April 28, 2016 ... 1,491.2 M (139.9), up 966% compared with the first quarter of ... Operating profit totaled SEK 589.1 M (loss: 18.8) and the operating ... SEK 7.12 (loss: 0.32) Cash flow from operations was ... , The 2016 revenue guidance is unchanged, SEK 7,000-8,500 M. ...
(Date:4/26/2016)... DUBLIN , April 27, 2016 ... of the  "Global Multi-modal Biometrics Market 2016-2020"  report ... ) , The analysts forecast ... a CAGR of 15.49% during the period 2016-2020.  ... a number of sectors such as the healthcare, ...
(Date:4/15/2016)... April 15, 2016  A new partnership announced ... accurate underwriting decisions in a fraction of the ... priced and high-value life insurance policies to consumers ... With Force Diagnostics, rapid testing (A1C, Cotinine ... readings (blood pressure, weight, pulse, BMI, and activity ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... Bangkok, Thailand (PRWEB) , ... May 25, 2016 ... ... the participation of a Thai delegation at BIO 2016 in San Francisco. Located ... private sector will be available to answer questions and discuss the Thai biotechnology ...
(Date:5/25/2016)... ... May 25, 2016 , ... Founder of the Fitzmaurice Hand ... and surgery of the hand by the National Board of Physicians and Surgeons, ... and beyond in his pursuit of providing the most comprehensive, effective treatment for ...
(Date:5/25/2016)... ... May 25, 2016 , ... Scientists at the University of Athens say ... mesothelioma may be hampering the research that could lead to one good one. Surviving ... read it now. , The team evaluated 98 mesothelioma patients who ...
(Date:5/25/2016)... ... May 25, 2016 , ... Lady had been battling ... her cruciate ligament in her left knee. Lady’s owner Hannah sought the help of ... board-certified veterinary surgeon, to repair her cruciate ligament and help with the pain of ...
Breaking Biology Technology:
Cached News: