HOME >> BIOLOGY >> NEWS
How does a zebrafish grow a new tail?

If a zebrafish loses a chunk of its tail fin, it'll grow back within a week. Like lizards, newts, and frogs, a zebrafish can replace surprisingly complex body parts. A tail fin, for example, has many different types of cells and is a very intricate structure. It is the fish version of an arm or leg.

The question of how cold-blooded animals re-grow missing tails and other appendages has fascinated veterinary and medical scientists. They also wonder if people, and other warm-blooded animals that evolved from these simpler creatures, might still have untapped regenerative powers hidden in their genes.

People are constantly renewing blood components, skeletal muscles and skin. We can regenerate liver tissue and repair minor injuries to bone, muscle, the tips of our toes and fingers, and the corneas of our eyes. Finding out more about the remarkable ability of amphibians and fish to re-grow complex parts might provide the information necessary to create treatments for people whose hearts, spinal cords, eyes or arms and legs have been badly hurt.

Scientists have discovered some of the genes and cell-to-cell communication pathways that enable zebrafish to restore their tail fins.

"The ability to regenerate body parts such as those that are damaged by injury or disease," said Dr. Randall Moon, professor of pharmacology at the University of Washington (UW), an investigator of the Howard Hughes Medical Institute, and a researcher in the UW Institute for Stem Cell and Regenerative Medicine, "involves creating cells that can take any number of new roles. This can be done by re-programming cells that already have a given function or by activating resident stem cells."

Developmental biologists know that a particular kind of cell-to-cell communication, called Wnt/Beta-catenin signaling, regulates the fate of these as-yet undeveloped cells as an embryo forms. Through a cascade of signals, cells waiting for their calling learn which
'"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
26-Dec-2006


Page: 1 2 3

Related biology news :

1. EPA selects Phylonix to screen compound library in zebrafish
2. Phylonix awarded National Science Foundation Phase II SBIR for zebrafish screening
3. Key to zebrafish heart regeneration uncovered
4. Temperature regulates circadian clock in zebrafish
5. Tiny zebrafish teaches researchers how to fight off a deadly cancer
6. Clues on cancer from a zebrafish model of melanoma
7. Glow-in-the-dark zebrafish at UH hold keys to biological clocks
8. Strawberry daiquiris -- the extra-healthy cocktail?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... its 2016 Annual Report on Form 10-K on Thursday April 13, ... ... the Investor Relations section of the Company,s website at http://www.nxt-id.com ... http://www.sec.gov . 2016 Year Highlights: ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ... appointment of independent Directors Mr. Robin D. Richards ... Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive ... their guidance and benefiting from their considerable expertise as we ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a ... biotechnology industries to improve patient outcomes and quality of life, will now be ... are being attributed to new regulatory requirements for all new drug products, including ...
(Date:10/11/2017)... CA, USA (PRWEB) , ... October 11, 2017 , ... ... to take place on 7th and 8th June 2018 in San Francisco, CA. The ... influencers as well as several distinguished CEOs, board directors and government officials from around ...
(Date:10/11/2017)... ... 11, 2017 , ... A new study published in Fertility ... fresh in vitro fertilization (IVF) transfer cycles. The multi-center matched cohort ... After comparing the results from the fresh and frozen transfer cohorts, the authors ...
(Date:10/10/2017)... ... October 10, 2017 , ... Dr. Bob Harman, founder ... local San Diego Rotary Club. The event entitled “Stem Cells and ... had 300+ attendees. Dr. Harman, DVM, MPVM was joined by two human doctors: ...
Breaking Biology Technology:
Cached News: