HOME >> BIOLOGY >> NEWS
Human brain is still evolving

Researchers who have analyzed sequence variations in two genes that regulate brain size in human populations have found evidence that the human brain is still evolving.

They speculate that if the human species continues to survive, the human brain may continue to evolve, driven by the pressures of natural selection. Their data suggest that major variants in these genes arose at roughly the same times as the origin of culture in human populations as well as the advent of agriculture and written language. The research team, which was led by Bruce T. Lahn, a Howard Hughes Medical Institute investigator at the University of Chicago, published its findings in two articles in the September 9, 2005, issue of the journal Science.

Their analyses focused on detecting sequence changes in two genes Microcephalin and "abnormal spindle-like microcephaly associated" (ASPM) across different human populations. In humans, mutations in either of these genes can render the gene nonfunctional and cause microcephaly a clinical syndrome in which the brain develops to a much smaller size than normal.

In earlier studies of non-human primates and humans, Lahn and his colleagues determined that both Microcephalin and ASPM showed significant changes under the pressure of natural selection during the making of the human species. "Our earlier studies showed that Microcephalin showed evidence of accelerated evolution along the entire primate lineage leading to humans, for the entire thirty to thirty-five million years that we sampled," he said. "However, it seemed to have evolved slightly slower later on. By contrast, ASPM has evolved most rapidly in the last six million years of hominid evolution, after the divergence of humans and chimpanzees."

In order to identify sequence changes that occurred in Microcephalin and ASPM in the evolutionary lineage leading to humans, Lahn and his colleagues took the following approach: They determined the DNA sequences of th
'"/>

Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
8-Sep-2005


Page: 1 2 3 4 5

Related biology news :

1. Human knowledge is based upon directed connectivity between brain areas
2. Human-like altruism shown in chimpanzees
3. Human genetic deserts are teeming with significant life
4. Human activities increasing carbon sequestration in forests
5. Cell Press announces new partnership with the American Society of Human Genetics
6. Human ancestors learned to walk upright in the trees, say experts
7. Humans arent the only ones with obesity problems
8. Center for Science Writings debate: Redesigning Humanity, March 21
9. Human pubic lice acquired from gorillas gives evolutionary clues
10. GenePOPS -- Sequencing Human History: The Genetics and Commerce of Personal Ancestry
11. Human trial results show excellent safety data, from Geovaxs DNA/MVA AIDS vaccines

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/6/2020)... , ... February 06, 2020 ... ... research organization (CRO) specializing in complex interventional medical device and pharmaceutical trials, ... Regulatory Strategy. In this newly established role, Dorothy oversees the development and ...
(Date:2/1/2020)... ... , ... Liver cancer, called hepatocellular carcinoma (HCC), occurs each year in more ... is the 5th most common cancer and the 2nd leading cause of cancer deaths. ... of HCC, while China has half of all patients suffering from liver cancer. The ...
(Date:1/29/2020)... Texas (PRWEB) , ... January 29, 2020 , ... ... DNA plasmid, announced it will start production of a DNA vaccine against the ... executed with Inovio Pharmaceuticals. A grant of up to $9 million from the ...
Breaking Biology News(10 mins):
(Date:2/5/2020)... Conn. (PRWEB) , ... February 04, 2020 , ... ... develops tools for characterizing microbiome populations down to the strain level, has announced ... will sell Shoreline Biome’s microbiome kits and other products to companies and research ...
(Date:2/3/2020)... BUDAPEST, Hungary and CAMBRIDGE, Mass. (PRWEB) , ... ... ... headquartered in Budapest with US offices in Cambridge, MA, announce that OmniType, the ... Access Program (EAP) from today. OmniType is a best-in-class product featuring locus-multiplexing and ...
(Date:1/28/2020)... ... January 28, 2020 , ... Today, Salimetrics announced an addition ... Salivary Total Human IgG Assay Kit exemplifies Salimetrics’ 20+ year commitment ... can extend the accuracy and ease of use of salivary bioscience into infectious ...
(Date:1/24/2020)... ... January 24, 2020 , ... The plastic and reconstructive ... Center in New Jersey epitomize the notion that plastic surgery is much more than ... in popular media. , Over the last 20 years NJ Top Docs, Dr. Andrew ...
Breaking Biology Technology:
Cached News: