HOME >> BIOLOGY >> NEWS
Hypertension in African Americans linked to two genomic regions

St. Louis, Feb. 9, 2005 -- A first-of-its-kind application of a novel statistical method of analysis to African Americans has identified regions on chromosomes 6 and 21 that likely harbor genes contributing to high blood pressure in that group. The novel statistical method, called admixture mapping, narrowed the search for genes related to hypertension, bringing researchers and doctors closer to finding more effective treatments.

Researchers at Stanford University School of Medicine, Loyola University Medical Center and Washington University School of Medicine in St. Louis, among others, collaboratively conducted the study, which will be published in the February issue of Nature Genetics and is available online.

In the U.S., 65 million people have high blood pressure, but it is found more often in African Americans than other groups. African Americans suffer from earlier and more severe hypertension and have a higher rate of death from stroke, heart disease, and kidney failure as a result.

The causes of hypertension are complex. Diet, exercise and stress contribute, but so do genetic factors. "It wouldn't be surprising if hypertension involved dozens of genes," says Dabeeru C. Rao, Ph.D., director of the Division of Biostatistics and one of the report's authors. "Unfortunately, in the past there have been conflicting reports about genes linked to the condition."

In a fresh approach to the problem, the researchers applied a genome-wide scan that compared how often genetic variations occur in people of African or European descent to how often they occur in African Americans.

As a group, African Americans can trace their ancestry largely to populations from both Africa and Europe. "The statistical technique we used is ideal for groups who have a trait with a higher occurrence--such as hypertension in African Americans--and who stem from two sets of ancestral populations that have differing genetic variations," Rao s
'"/>

Contact: Gwen Ericson
ericsong@wustl.edu
314-286-0141
Washington University School of Medicine
9-Feb-2005


Page: 1 2 3

Related biology news :

1. ISNs Nexus Hypertension-Kidney debate
2. Penn researchers awarded $1.1 million for Pulmonary Hypertension Center
3. Hypertension risk in African-Americans linked to genetics, Stanford study finds
4. Clues to future evolution of HIV come from African green monkeys
5. First all-African produced genetically engineered maize is resistant to maize streak virus
6. New clue why MS affects African-Americans differently than Caucasians
7. Stressed-out African naked mole-rats may provide clues about human infertility
8. Slow wave activity during sleep is lower in African-Americans than Caucasians
9. OSA symptoms more common among African-American women than Caucasians
10. West African Ocean sediment core links monsoons to global climate evolution
11. African carnage -- 1 years seized ivory likely came from 23,000 elephants

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Hypertension African Americans linked two genomic regions

(Date:2/5/2015)... Carolina , 5. Februar 2015 /PRNewswire/ ... als spezialisiertes Logistikunternehmen und hat eine neue ... klinische Logistikfirma (Clinical Logistics Organization – CLO) ... neuen Kampagne lautet First , mit ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
(Date:2/5/2015)... , January 28, 2015 ... Analysis, Size And Segment Forecasts To 2020 has Been ... IR camera market is expected to reach USD 5.10 ... Grand View Research, Inc. IR cameras help identify the ... are expected to witness surging demand in medical imaging ...
(Date:1/22/2015)... 22, 2015 Research and Markets ( http://www.researchandmarkets.com/research/4trb7t/biometrics_a ) ... Global Market Overview" report to their offering. , ... ensure that an individual is who she/he is claiming to ... of a person,s unique physical characteristics, such as fingerprint, hand ...
Breaking Biology News(10 mins):Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 3Biometrics - A Global Market Overview 2Biometrics - A Global Market Overview 3
(Date:3/4/2015)... Lancée par l,Assistance ... en décembre 2011, l,étude collaborative française randomisée ... compare   l es microsphères en résine ... le carcinome hépatocellulaire avancé, a recruté plus de ...   ; les résultats sont attendus fin 2016. ...
(Date:3/3/2015)... and TORONTO, March 3, 2015 /PRNewswire/ - Aptose Biosciences ... new therapeutics and molecular diagnostics that target the underlying ... quarter and seventh-month period ended December 31, 2014. ... fiscal year end from May 31 to December 31. ... are reporting today are for the quarter and the ...
(Date:3/3/2015)... WASHINGTON , March 3, 2015 NASA astronaut ... his launch this month to spend a year living and ... live satellite interviews from 5:30 to 7 a.m. EDT Monday, ... Moscow as he completes the final weeks of ... by a video on NASA Television highlighting his mission training ...
(Date:3/3/2015)... ON , March 3, 2015 /PRNewswire/ - BIOREM Inc. (TSXV: ... $3.7 million.  The orders are for odour control projects in ... and Asia . "Bidding activity ... , President and CEO. "After a high volume year for bidding ... into the New Year.  The recent orders reflect the organization,s renewed ...
Breaking Biology Technology:Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 2Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 3Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 4Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 5Traitement du cancer primitif du foie : Recrutement terminé pour l'étude SARAH et résultats attendus fin 2016 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 2Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 3Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 4Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 5Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 6Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 7Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 8Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 9Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 10Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 11Aptose Biosciences reports results for the quarter and seven months ended December 31, 2014 12NASA Astronaut Scott Kelly Available for Interviews before One-Year Space Station Mission 2
Cached News: