HOME >> BIOLOGY >> NEWS
Identification of specific genes predicts which patients will respond to Hepatitis C treatment

For the first time, physicians at University Health Network and University of Toronto have identified a small subset of genes that can predict whether a patient with chronic Hepatitis C will be able to respond to current treatments.

These genes could also become the basis of a simple new test in the future to predict which patients will respond to therapy.

The study, published in the May issue of the American Gastroenterological Association's Gastroenterology, found that the difference between those patients who responded to treatment and those who did not was the level of expression whether the genes were turned on or turned off - of 18 genes.

"Our results demonstrate that a relatively small number of genes can predict response to therapy. These genes may be important to the ability of the patient to eliminate the virus, so studying these genes in more detail will hopefully lead to novel antiviral treatments," said Dr. Ian McGilvray, the senior author of the study. Dr. McGilvray is a transplant surgeon at Toronto General Hospital, University Health Network and an Assistant Professor of Surgery at the University of Toronto. "By manipulating the products of these genes we might be able to improve treatment responses to this chronic disease."

"This information is helpful for patients because it's one more piece of evidence that we hope will encourage 'responder' patients to start and continue treatment for Hepatitis C, despite it's many side effects," said Dr. Jenny Heathcote, a hepatologist at Toronto Western Hospital, University Health Network and Professor of Medicine at University of Toronto, who contributed to the study and treats many of the patients in the study. "We want to be able to give patients as much information as we can, so that they can make the best decisions about their treatment options."

Tony Angelini, 42, was one of the patients in the study who responded to treatment. He is now clear of t
'"/>

Contact: Alex Radkewycz
alexandra.radkewycz@uhn.on.ca
416-340-3895
University of Toronto
2-May-2005


Page: 1 2 3

Related biology news :

1. Identification of genetic risk factor for coeliac disease promises improved treatment
2. Identification of carbon dioxide receptors in insects may help fight infectious disease
3. Identification of a protein important for Hepatitis B replication
4. UCI launches effort to develop patient-specific stem cell lines
5. Salk researchers discover first gene that specifically links calorie restriction to longevity
6. Progress toward a targeted therapy for a specific form of leukemia
7. Joslin study reveals how a specific fat type can protect against weight gain and diabetes
8. Scientists identify specific enzymes that make meningitis hard to fight
9. Nanotech safety needs specific government risk research strategy and funding
10. A new male-specific gene in algae unveils an origin of male and female
11. Nerve fibers need specific growth factor chemical to form connections within the brain

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2020)... ... May 26, 2020 , ... ... today announced that Gritstone Oncology, Inc., a clinical-stage biotechnology company developing cancer ... and TCR-based therapeutics, has implemented Genedata Biologics ® within their R&D ...
(Date:5/21/2020)... ... ... Law Enforcement has always been a highly stressful career – serving to ... men and women put them constantly in harm’s way both from the criminal element ... had to face very high daily stress. Now, COVID-19 introduces another even greater degree ...
(Date:5/14/2020)... , ... May 14, 2020 , ... ... board for medical sales representatives, found the 2019 average medical sales rep total ... risk being shadowed by uncertainties amid the COVID-19 global crisis. , The MedReps ...
Breaking Biology News(10 mins):
(Date:4/7/2020)... ... April 06, 2020 , ... Red ... life sciences industry, has announced the release of at-home virtual learning resources for ... is the health and safety of our employees as we continue to implement ...
(Date:4/1/2020)... , ... March 30, 2020 , ... ... telehealth developer Reliant Immune Diagnostics (RID), formed earlier this year to bring telehealth ... by creating in-home tests for COVID-19. Company officials are currently?awaiting an Emergency Use ...
(Date:4/1/2020)... SALT LAKE CITY, and LA JOLLA, Calif. (PRWEB) , ... March ... ... and characterization tools, and La Jolla Institute for Immunology (LJI), announced today that they ... few days allowing CoVIC to move therapeutic candidates to the clinic as early as ...
(Date:3/27/2020)... ... March 25, 2020 , ... ... located centrally in the midwest for high-quality, quick-turn, board-certified reporting. In an ... motivated, independent, professional team that is focused on incredible quality, turnaround time ...
Breaking Biology Technology:
Cached News: