Improved blood safety measures from Pall can increase platelet av...( ospitals. Dr. Holme provided an ...)

Dr. Holme provided an overview of the results from a series of studies conducted by research institutions in the U.S. and Canada that demonstrate the value of prestoraged pooled platelets. In vivo studies showed that prestoraged pooled platelets have an equivalent clinical response (the number of platelets that continue to circulate in the human body post-transfusion) to platelets pooled at the time of transfusion. The pooled and stored platelets also showed equivalent quality based on standard quality criteria and measures.

Steven Young, Ph.D., Scientific Director Microbiology & Virology, Tricore Reference Laboratories, presented a study on bacteria detection of pooled platelet concentrates, which evaluated the ability of the Pall eBDS System to detect 10 different bacteria that can contaminate platelets. The results of this study found that the Pall eBDS System, one of the most sensitive culture methods, was effective in detecting bacteria (greater than 99 percent) in pooled platelets.

Dr. Young concludes, "The ability to store random donor platelets concentrates as a pool would provide significant benefits such as having a therapeutic dose ready in emergency situations, reducing pool outdating, and enabling a simplified method for bacteria detection."

This month Pall Corporation was granted FDA clearance to market the Pall AcrodoseTM PL System, which provides a therapeutic dose of leukoreduced platelets that are tested for bacteria contamination with the integrated Pall eBDS technology. The new system enables blood centers to pool whole blood derived platelets and conduct a single state-of-the-art bacterial contamination test to enhance platelet safety and availability. The resulting AcrodoseSM Platelets are transfusion-ready and reduce the cost burden to hospitals by eliminating the need for further processing and testing.

Adding to this body of knowledge, Joseph D. Sweeny, M.D., Medical Director Blood
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Contact: Marcia Katz
marcia_katz@pall.com
516-801-9128
Pall Corporation
17-Oct-2005