HOME >> BIOLOGY >> NEWS
In young rats, researchers find a reaction to spinal cord injury that speeds recovery

hey are completely severed, but researchers believe that in a partial injury, surviving nearby axons that serve the same general body area and function can "sprout" new connections to those injured nerve cells that have lost some of their axons. In studying spinal cord injury in rats − the usual model for this kind of investigation − researchers had thought that younger rats ("pups") regain function faster because this sprouting occurs more quickly and proficiently than in older rats. "Just as young trees grow more quickly if you prune them than do older trees, we thought than in young animals, surviving axons would sprout new, and longer, axonal connections more readily," Wrathall said.

But their findings surprised them. "We didn't see that sprouting was faster or better in younger than in adult rats after a partial spinal cord injury," she said. Instead, they saw distinctions in what occurred in cells within the spinal cord at the site of injury. Leung and Wrathall specifically discovered that in the pups, specialized neural stem cells grew vigorously after injury and within one week, many oligodendrocytes, cells whose function is to provide a protective myelin sheath to axons, were produced..

The researchers believe that these activated cells wrap nearby surviving axons with extra myelin sheathing in order to protect them and support their function after injury.

"The ability of axons to transmit their signals is greatly dependent on the insulation provided by their myelin sheaths, and we know that axons near the site of injury eventually can die due to loss of this myelin," Wrathall said. "So we believe these stem cells work to protect healthy axons against toxic factors in the microevironment."

Adult rats do not activate these specialized cells to the same extent as the pups do after injury, for reasons that are not understood, she added.

"We hadn't expected these results, but they are exciting for the
'"/>

Contact: Laura Cavender
lsc6@georgetown.edu
202-687-5100
Georgetown University Medical Center
8-Nov-2006


Page: 1 2 3

Related biology news :

1. Universes stringy birth revealed by young Czech scientist in EURYI winning project
2. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
3. High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
4. Throwing motion in young baseball players may actually protect shoulder
5. Eavesdropping comes naturally to young song sparrows
6. Cannibalism of the young allows individual fish to specialize
7. Study to probe how healthy younger adults make use of genetic tests
8. Cat hair at home poses an allergy risk, particularly for young children
9. In young mice, gregariousness seems to reside in the genes
10. Three young scientists at Yale honored with Sloan Foundation Fellowships
11. PET imaging shows young smokers quick benefit of quitting

Post Your Comments:
(Date:4/17/2014)... France have hit on a novel method to ... correct and most effective treatment possible., Kidney stones ... and developing world. If left untreated, apart from ... failure and other complications. In many patients treated ... a more effective pathological approach to diagnosis and ...
(Date:4/17/2014)... Current Biology on April 17 have discovered ... Brazilian insects, which represent four distinct but related species ... example of an animal with sex-reversed genitalia. , ... animals, Neotrogla is the only example in ... Yoshizawa from Hokkaido University in Japan. , During copulation, ...
(Date:4/17/2014)... at the University of Texas Medical Branch at ... women treated with radiation for cervical cancer should ... , The UTMB researchers, finding a high ... survivors treated with radiation, offer new recommendations that ... cancer screening about eight years after their initial ...
Breaking Biology News(10 mins):In sex-reversed cave insects, females have the penises 2Radiation therapy for cervical cancer increases risk for colorectal cancer 2
(Date:1/15/2014)... interface is the device," Nobel laureate Herbert Kroemer ... be found at the junctures where layers of ... nanotechnology, the interfaces between layers of metal oxides ... high-tech favorites as spintronics, high-temperature superconductors, ferroelectrics and ...
(Date:1/15/2014)... Jan. 15, 2014   Niagara Thermal Products is ... Buffalo BioBlower Technologies LLC ("B3") as the critical thermal ... award from the Army Corps of Engineers.  B3 has ... all biological contaminants and destroys VOCs and other chemical ...
(Date:1/15/2014)... OXFORD, England and SAN JOSE, California ... an international biotechnology company developing antibody-drug conjugates for cancer, today ... its Board of Directors. Dr Reynolds has over 20 years, ... Chief Medical Officer at Seattle Genetics. "I am ...
(Date:1/15/2014)... A study has been launched to test ... track could help to tackle the problem of obesity.  This ... GP surgery based in Stowmarket) and academics at University Campus ... Telemetry technology, which is inspired by equipment used to collect ...
Breaking Biology Technology:A deeper look at interfaces 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4
Cached News: