HOME >> BIOLOGY >> NEWS
In young rats, researchers find a reaction to spinal cord injury that speeds recovery

hey are completely severed, but researchers believe that in a partial injury, surviving nearby axons that serve the same general body area and function can "sprout" new connections to those injured nerve cells that have lost some of their axons. In studying spinal cord injury in rats − the usual model for this kind of investigation − researchers had thought that younger rats ("pups") regain function faster because this sprouting occurs more quickly and proficiently than in older rats. "Just as young trees grow more quickly if you prune them than do older trees, we thought than in young animals, surviving axons would sprout new, and longer, axonal connections more readily," Wrathall said.

But their findings surprised them. "We didn't see that sprouting was faster or better in younger than in adult rats after a partial spinal cord injury," she said. Instead, they saw distinctions in what occurred in cells within the spinal cord at the site of injury. Leung and Wrathall specifically discovered that in the pups, specialized neural stem cells grew vigorously after injury and within one week, many oligodendrocytes, cells whose function is to provide a protective myelin sheath to axons, were produced..

The researchers believe that these activated cells wrap nearby surviving axons with extra myelin sheathing in order to protect them and support their function after injury.

"The ability of axons to transmit their signals is greatly dependent on the insulation provided by their myelin sheaths, and we know that axons near the site of injury eventually can die due to loss of this myelin," Wrathall said. "So we believe these stem cells work to protect healthy axons against toxic factors in the microevironment."

Adult rats do not activate these specialized cells to the same extent as the pups do after injury, for reasons that are not understood, she added.

"We hadn't expected these results, but they are exciting for the
'"/>

Contact: Laura Cavender
lsc6@georgetown.edu
202-687-5100
Georgetown University Medical Center
8-Nov-2006


Page: 1 2 3

Related biology news :

1. Universes stringy birth revealed by young Czech scientist in EURYI winning project
2. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
3. High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
4. Throwing motion in young baseball players may actually protect shoulder
5. Eavesdropping comes naturally to young song sparrows
6. Cannibalism of the young allows individual fish to specialize
7. Study to probe how healthy younger adults make use of genetic tests
8. Cat hair at home poses an allergy risk, particularly for young children
9. In young mice, gregariousness seems to reside in the genes
10. Three young scientists at Yale honored with Sloan Foundation Fellowships
11. PET imaging shows young smokers quick benefit of quitting

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/2/2017)... 2017  Central to its deep commitment to ... The Japan Prize Foundation today announced the laureates ... the envelope in their respective fields of Life ... are being recognized with the 2017 Japan Prize ... contribute to the advancement of science and technology, ...
(Date:1/26/2017)...  Crossmatch, a leading provider of security and identity ... combatting fraud, waste and abuse in assistance operations around ... on Disaster Relief conference in Panama City ... and foreign assistance organizations throughout Latin America ... a largely unacknowledged problem in the foreign assistance and ...
(Date:1/24/2017)... PHILADELPHIA , Jan. 24, 2017  It ... a baby,s sock that monitors vital signs and ... instance, an infant,s oxygen saturation level drops. But ... undue alarm to parents, with no evidence of ... "These devices are marketed aggressively to parents of ...
Breaking Biology News(10 mins):
(Date:2/27/2017)... , Feb. 27, 2017 AcelRx Pharmaceuticals, ... on the development and commercialization of innovative therapies ... today the U.S. Food and Drug Administration (FDA) ... under section 505(b)(2) for DSUVIA™ (formerly ARX-04) (sufentanil ... patients with moderate-to-severe acute pain in a medically ...
(Date:2/27/2017)... ... February 27, 2017 , ... The Catalyst ... few in the Midwest offering premix services and private label organic services. , The ... hens, according Jos Zamzow, chief operating officer of Dynamite Marketing, which owns the facility. ...
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... Chef Jodi ... wine scene. Making stops in several cities, she gained a number of delicious ... began in Stellenbosch, a town in South Africa’s Western Cape province. It is ...
(Date:2/24/2017)... Blood Corporation (NYSE: CO ) ("CCBC" or ... laboratory testing, hematopoietic stem cell processing and stem cell ... the third quarter and first nine months of fiscal ... Quarter of Fiscal 2017 Highlights Revenues ... 18.6% to RMB200.9 million ($28.9 million). ...
Breaking Biology Technology:
Cached News: