HOME >> BIOLOGY >> NEWS
In young rats, researchers find a reaction to spinal cord injury that speeds recovery

hey are completely severed, but researchers believe that in a partial injury, surviving nearby axons that serve the same general body area and function can "sprout" new connections to those injured nerve cells that have lost some of their axons. In studying spinal cord injury in rats − the usual model for this kind of investigation − researchers had thought that younger rats ("pups") regain function faster because this sprouting occurs more quickly and proficiently than in older rats. "Just as young trees grow more quickly if you prune them than do older trees, we thought than in young animals, surviving axons would sprout new, and longer, axonal connections more readily," Wrathall said.

But their findings surprised them. "We didn't see that sprouting was faster or better in younger than in adult rats after a partial spinal cord injury," she said. Instead, they saw distinctions in what occurred in cells within the spinal cord at the site of injury. Leung and Wrathall specifically discovered that in the pups, specialized neural stem cells grew vigorously after injury and within one week, many oligodendrocytes, cells whose function is to provide a protective myelin sheath to axons, were produced..

The researchers believe that these activated cells wrap nearby surviving axons with extra myelin sheathing in order to protect them and support their function after injury.

"The ability of axons to transmit their signals is greatly dependent on the insulation provided by their myelin sheaths, and we know that axons near the site of injury eventually can die due to loss of this myelin," Wrathall said. "So we believe these stem cells work to protect healthy axons against toxic factors in the microevironment."

Adult rats do not activate these specialized cells to the same extent as the pups do after injury, for reasons that are not understood, she added.

"We hadn't expected these results, but they are exciting for the
'"/>

Contact: Laura Cavender
lsc6@georgetown.edu
202-687-5100
Georgetown University Medical Center
8-Nov-2006


Page: 1 2 3

Related biology news :

1. Universes stringy birth revealed by young Czech scientist in EURYI winning project
2. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
3. High rates of HIV infection documented among young Nepalese girls sex-trafficked to India
4. Throwing motion in young baseball players may actually protect shoulder
5. Eavesdropping comes naturally to young song sparrows
6. Cannibalism of the young allows individual fish to specialize
7. Study to probe how healthy younger adults make use of genetic tests
8. Cat hair at home poses an allergy risk, particularly for young children
9. In young mice, gregariousness seems to reside in the genes
10. Three young scientists at Yale honored with Sloan Foundation Fellowships
11. PET imaging shows young smokers quick benefit of quitting

Post Your Comments:
(Date:8/17/2015)... , Aug. 17, 2015  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market ... new sales campaign for Q4 2015. The new marketing ... team consisting of Amplitude Marketing Group ( http://amplitudemarketing.com/ ) ... Group is a leader in retail driven marketing and ...
(Date:8/12/2015)... 12, 2015 As the digital ... innovation and advanced biometrics technology is accelerating beyond expectations.  ... rely on using their credit cards, the digital currency, ... for payment services led by companies in the space ... Google, Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ...
(Date:8/12/2015)... 12, 2015  Synaptics Inc. (NASDAQ: SYNA ... today announced that four of its fingerprint ID ... officially been named FIDO Certified™ by the Fast ... certification, Synaptics, Natural ID™ fingerprint solutions are fully ... (UAF) standard and are interoperable among other products ...
Breaking Biology News(10 mins):NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 2NXT-ID, Inc. Launches Sales Campaign for Wocket Smart Wallet with Award Winning Marketing Team 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 2Synaptics Announces FIDO Certification of Natural ID Fingerprint Solutions 3
(Date:9/3/2015)... , Sept. 3, 2015 /PRNewswire/ - bioLytical Laboratories ... to announce its study " Sensitivity of a rapid ... is enhanced by its affinity for HIV gp41 IgM ... Clinical Virology.  This study highlights INSTI,s ability to detect ... their findings at the 8 th annual International ...
(Date:9/3/2015)... ... 03, 2015 , ... If you plan to attend the 27th annual ... also want to sign up for the tour of Framingham State University's newest addition ... walk through of the (8) chemistry teaching labs that are exclusively utilizing (49) ...
(Date:9/2/2015)... DUBLIN , Sep. 02, 2015 ... ) has announced the addition of Jain PharmaBiotech,s ... Markets and Companies" to their offering. ... markets based on technologies and applications. The report ... basis for estimation of markets. Technologies include array ...
(Date:9/2/2015)... Biovista Inc. is glad to ... BeHEARD science challenge, a global competition hosted by the ... to the latest life science innovations and technologies. ... analytics capability to support Steven Laffoon and ... of Niemann-Pick Disease Type A (NPA), a rare and ...
Breaking Biology Technology:bioLytical's INSTI HIV Test Detects gp41 specific IgM Antibodies 2bioLytical's INSTI HIV Test Detects gp41 specific IgM Antibodies 3Erlab Invites You to Tour the Largest Installation of Filtered Fume Hoods in the World 2Global Biochips and Microarrays Technologies, Markets and Companies Report 2015 with Market Size in 2014 and Projected Value for the Years 2019 and 2024 2Biovista Sponsors Wylder Nation Foundation's Research on Acid Sphingomyelinase Deficiency 2
Cached News: