HOME >> BIOLOGY >> NEWS
International team of scientists complete fungal genomic sequences

Humans have a love-hate relationship with the aspergilli, a group of about 185 different species of fungus: several species are human athogens, while others are the basis for the production of human food and industrial enzymes. Now, an international team of scientists have determined and compared the genome sequences of three aspergilli Aspergillus fumigatus, a potentially deadly human pathogen, A. oryzae, used in the production of soy sauce and sake, and A. nidulans, a model genetic organism. Their findings, published in three papers in the December 22 issue of Nature, advance our understanding of the molecular basis of Aspergillus infection, provide insight into the forces driving genome evolution, and identify new genomic functional elements.

"The comparison of these organisms gives us a wealth of information about gene regulation and genome evolution that apply to the study of all eukaryotes, including humans," said James Galagan, associate director of Microbial Genome Analysis and Annotation at the Broad Institute. "We were most excited about being able to relate genome evolution to sexual reproduction, a very specific and important physiological difference between the three aspergilli." Unlike A. nidulans, which has a sexual cycle, A. oryzae and A. fumigatus were believed to be asexual, but the comparative analysis suggests that both species maintain the genetic wherewithal for sexual reproduction. If confirmed, this raises the potential for developing powerful genetic tools for both organisms, with far reaching implications for medicine (A. fumigatus) and industry (A. oryzae).

Broad Institute scientists and their colleagues determined the genome sequence Aspergillus nidulans and, led by Galagan, performed comparative analysis of the three aspergilli. The direct genome sequence comparison of three species of aspergilli is of particular interest to scientists, given the long evolutionary history of these species as well as their different e
'"/>

Contact: Michelle Nhuch, Broad Institute
nhuch@broad.mit.edu
617-252-1064
Broad Institute of MIT and Harvard
21-Dec-2005


Page: 1 2

Related biology news :

1. National Ecological Observatory Network featured at ESA/SER Joint International Conference
2. International team to honor 30th anniversary of deep-sea vent discovery in Galpagos
3. 2nd International EuroFIR Congress
4. Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
5. Smithsonian hosts Polar Science Symposium to celebrate International Polar Year 2007-2008
6. Eduardo Slatopolsky honored with 2007 ISN Amgen International Prize
7. 4th International Conference on Ethical Issues in Biomedical Engineering
8. International risk research strategy and funding needed for nanotech safety
9. Pezcoller Foundation-AACR International Award for Cancer Research recognizes Mina J. Bissell
10. International Astronautical Federation joins project to protect World Heritage sites
11. International Society for Heart and Lung Transplantation 27th Annual Meeting and Scientific Sessions

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: