HOME >> BIOLOGY >> NEWS
JCI Table of contents August 1, 2005

diated lipid uptake and atherogenesis. The CD36 and SR-A null mice had increased aortic lesion areas, compared to controls. The lesions appeared to be more advanced than those seen in the control mice. These results suggest that scavenger receptor-mediated lipid uptake is not pro-atherosclerotic, as has been reported. In fact, the data presented suggest that scavenger receptor function is protective in atherosclerosis.

In an accompanying commentary, Joseph Witztum discusses potential reasons for the discordant results. He mentions that the reasons why the data are different from previous studies is not quite clear, but that the "data presented by Moore, et al. will cause all of us to stop and reevaluate and to undertake much more experimentation and thought."

TITLE: Loss of lipid uptake via class A scavenger receptors or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

AUTHOR CONTACT:
Mason Freeman
Massachusetts General Hospital, Boston, MA USA
Phone: 617-726-5906; Fax: 617-726-2879; E-mail: freeman@molbio.mgh.harvard.edu

View the PDF of this article at: https://www.the-jci.org/article.php?id=24061

ACCOMPANYING COMMENTARY:

TITLE: You are right too!

AUTHOR CONTACT:
Joseph L. Witztum
University of California San Diego, La Jolla, CA USA
Phone: 858-534-4347; Fax: 858-534-4347; E-mail: jwitztum@ucsd.edu

View the PDF of this article at: https://www.the-jci.org/article.php?id=26130


'"/>

Contact: Stacie Bloom
press_releases@the-jci.org
212-342-4159
Journal of Clinical Investigation
1-Aug-2005


Page: 1 2 3 4 5 6 7 8 9 10 11

Related biology news :

1. JCI Table of Contents -- July 2, 2007
2. JCI Table of Contents: July 13, 3006
3. JCI Table of Contents, June 15 2006
4. JCI Table of Contents, April 13, 2006
5. JCI Table of Contents, March 1, 2005
6. JCI table of contents: Aug. 9, 2007
7. JCI table of contents: August 1, 2007
8. JCI table of contents -- July 26, 2007
9. JCI table of contents: July 19, 2007
10. JCI table of contents: July 12, 2007
11. JCI table of contents: June 21, 2007

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... -- The American College of Medical Genetics and Genomics was once ... one of the fastest-growing trade shows during the Fastest 50 ... Las Vegas . Winners ... each of the following categories: net square feet of paid ... The 2015 ACMG Annual Meeting was ranked 23 out of ...
(Date:6/22/2016)... On Monday, the Department of Homeland Security ... solutions for the Biometric Exit Program. The Request for ... (CBP), explains that CBP intends to add biometrics to ... United States , in order to deter visa ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
(Date:6/20/2016)... , June 20, 2016 Securus Technologies, ... technology solutions for public safety, investigation, corrections and ... prisons involved, it has secured the final acceptance ... facilities for Managed Access Systems (MAS) installed. Furthermore, ... facilities to be installed by October, 2016. MAS ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... 2016 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" or "the ... major shareholders, Clean Technology Fund I, LP and Clean ... based venture capital funds which together hold approximately ... fully diluted, as converted basis), that they have entered ... equity holdings in Biorem to TUS Holdings Co. Ltd. ...
(Date:6/27/2016)... ... 27, 2016 , ... Rolf K. Hoffmann, former senior vice ... University of North Carolina Kenan-Flagler Business School effective June 27. , ... with a focus on the school’s international efforts, leading classes and participating in ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... While the ... such as the Cary 5000 and the 6000i models are higher end machines that ... the height of the spectrophotometer’s light beam from the bottom of the cuvette holder. ...
(Date:6/23/2016)... /PRNewswire/ - FACIT has announced the creation of ... company, Propellon Therapeutics Inc. ("Propellon" or "the Company"), ... portfolio of first-in-class WDR5 inhibitors for the treatment ... represent an exciting class of therapies, possessing the ... cancer patients. Substantial advances have been achieved with ...
Breaking Biology Technology:
Cached News: