HOME >> BIOLOGY >> NEWS
JCI table of contents -- April 19, 2007

with IgG antibodies that recognize ovalbumin. The antibodies were shown to enable immune cells known as dendritic cells to take up dying pancreatic cells expressing ovalbumin and present the ovalbumin to CD8+ T cells (a process known as cross-presentation) in a form that they could "see". Cross-presentation required that the dendritic cells express activating IgG1 receptors. Because ovalbumin-specific antibodies were required for the activation of disease-causing T cells the authors suggest that developing approaches to prevent autoantibodies from enabling dendritic cells to cross-present self antigen to T cells might provide a new approach to treat autoimmune diseases.

TITLE: Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance

AUTHOR CONTACT:

Raphael Clynes
Columbia University, New York, New York, USA.
Phone: (212) 305-5289; Fax: (212) 305-1392; E-mail: rc645@columbia.edu.

View the PDF of this article at: https://www.the-jci.org/article.php?id=29470


'"/>

Contact: Brooke Grindlinger
press_releases@the-jci.org
212-342-9006
Journal of Clinical Investigation
19-Apr-2007


Page: 1 2 3 4 5 6 7

Related biology news :

1. Antioxidant overload may underlie a heritable human disease
2. JCI table of contents: Aug. 9, 2007
3. JCI table of contents: August 1, 2007
4. US Department of Defense awards $1.6 million for implantable biochip research
5. More fish oil, less vegetable oil, better for your health
6. JCI table of contents -- July 26, 2007
7. JCI table of contents: July 19, 2007
8. JCI table of contents: July 12, 2007
9. JCI table of contents: June 21, 2007
10. JCI table of contents: June 14, 2007
11. Food safety begins as vegetables grow

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2018)... ... 22, 2018 , ... RURO, Inc., an industry-leading lab software ... rapidly growing cloud-based laboratory information system. , With the success of the streamlined ... digit growth throughout 2018, the RURO team has been hard at work expanding ...
(Date:8/21/2018)... ... August 21, 2018 , ... Whether it be online or ... to offering customers a successful experience. When browsing the new site in ... products, with relevant details such as technical manuals, application notes, and instrument compatibility ...
(Date:8/17/2018)... ... 2018 , ... Cryo-Cell International, Inc. (OTC:QB Markets Group Symbol: ... store stem cells in 1992, announced that Arthur Ellis, JD, Board President of ... Managing Partner IsZo Capital, have joined the Company’s Board of Directors. , Arthur ...
Breaking Biology News(10 mins):
(Date:8/21/2018)... ... August 21, 2018 , ... ... device compliance and commercialization, has just released a new paper discussing systems ... by Dr. Mario Kossmann, ESEP at the 28th Annual INCOSE International Symposium, ...
(Date:8/17/2018)... Fla. (PRWEB) , ... August 16, 2018 , ... The ... when Astro Pak acquired Chemko Technical Services in 2016. Chemko had a well established ... supporting on-site work at KSC on projects such as the ongoing work at the ...
(Date:8/17/2018)... ... August 16, 2018 , ... Ambry ... from the AmbryShare project were published today in JAMA Oncology, identifying new and ... study ever conducted. , Every year hereditary breast cancer affects more than 20,000 ...
(Date:8/14/2018)... ... August 13, 2018 , ... Labconco ... and biological safety cabinets. In addition, Labconco produces other lab equipment, such as ... its commitment to quality and consistency in design and manufacturing. , Through ...
Breaking Biology Technology:
Cached News: