HOME >> BIOLOGY >> NEWS
Jefferson scientists find guardian gene's choices crucial to stopping cancer process

player in the cancerous process it's nearly always mutated or inactivated in cancer that continuing to understand more about how it works will likely have significant implications for cancer research," says Dr. McMahon. "We wouldlike to understand the interplay between this newly identified pathway and others involved in p53 and cancer.

"Since p53 can make this decision, this might give some insight into which function of p53 is more important in which tissues," says co-author Stephen Sykes, a Ph.D. candidate at the University of Pennsylvania. "For example, K120 (lysine 120) mutations cause tumors in the prostate, but are not so much involved in causing immune system cancers such as lymphomas. That could suggest that p53's potential to cause cell death could be more important in certain tissues than in others. In the future, if someone could develop therapies that could specifically activate p53's potential to drive programmed cell death versus the cell cycle arrest potential, it might influence how a doctor might choose to treat a certain type of cancer.

"This may potentially enable the development of a cancer drug that would stimulate the enzymes to promote this modification driving p53 to apoptosis."


'"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
5-Jan-2007


Page: 1 2

Related biology news :

1. Jefferson scientists patent dramatically improves
2. Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
3. Tiny genes may increase cancer susceptibility, Jefferson scientists find
4. Jefferson scientists use gene therapy to reverse heart failure in animals
5. Jefferson researchers discovery may change thinking on how viruses invade the brain
6. Jefferson scientists identify protein key to breast cancer spread, potential new drug target
7. Jefferson scientists find rabies-based vaccine could be effective against HIV
8. Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
9. Targeting the adrenal gland could be key strategy against heart failure, Jefferson scientists show
10. Jefferson researchers uncover new way nature turns genes on and off
11. Jefferson researchers develop combined procedure for uterine preservation in treating fibroids

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/3/2019)... (PRWEB) , ... June 03, 2019 , ... Stay on ... biotech, medical device and food industries. Access to all webinars is free, so be ... relevant in your field! , Visit http://www.xtalks.com to see our upcoming webinars: ...
(Date:5/31/2019)... ... May 30, 2019 , ... Researchers ... Mayo Clinic, have documented significant differences in the prevalence of hereditary genetic mutations, ... compared to non-Hispanic White women. Results will be presented at the 2019 American ...
(Date:5/31/2019)... ... May 31, 2019 , ... The OilComm ... Houston, TX, announced today that Ben Reiter, Senior Writer at Sports Illustrated and ... October 3rd.     , Reiter predicted the Houston Astros would win the MLB championship ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 29, 2019 , ... ... USPTO providing proprietary interest to our methodology, processes, and diagnostic techniques. The ... TREATMENT… extends Somnology’s IP rights including our proprietary sleep scoring methodology. The ...
(Date:5/21/2019)... ... 21, 2019 , ... DuPont Nutrition & Biosciences (DuPont) and ... Brewing Conference dedicated to sharing brewing knowledge, strengthening relationships and discussing best practices ... through a partnership with “Ethiopia Invest”, will run through May 23, 2019, in ...
(Date:5/8/2019)... ... May 07, 2019 , ... Standing at 16.2 hands, Atlas is on the large ... a drill team and barrel racing, among other activities. When loping around a corner ... went from being a busy horse to only being able to walk. Fortunately Atlas’ ...
(Date:5/2/2019)... ... 2019 , ... The centuries old practice of brewing beer thrives today across ... and even home brewing clubs scattered across the nation. , But proper beer ... can produce a superb product. Students at South Dakota School of Mines & ...
Breaking Biology Technology:
Cached News: