HOME >> BIOLOGY >> NEWS
Jefferson scientist's patent dramatically improves

(PHILADELPHIA) A basic scientist in the Department of Surgery at Jefferson Medical College and the Kimmel Cancer Center at Jefferson has shared a patent on what may someday be a ubiquitous tool in DNA analysis. The discovery could have a range of applications, from forensics to cloning to bioterrorism.

Jonathan Brody, Ph.D., assistant professor of surgery and colleague Scott Kern, M.D., at Johns Hopkins University in Baltimore, have developed a technique that makes a DNA separation technique called electrophoresis five times faster and less expensive than now is possible. It could save millions of dollars a year, just by speeding up processes, says Dr. Brody.

Most molecular biology-based techniques involve electrophoresis, the main way scientists analyze DNA. But the ingredients involved in the process have been unchanged for 30 years. It turns out that all of the buffers people have been using for 30 years have been the wrong choice, he says, because the standard method is more expensive and takes longer. This solution that we found is literally a better, faster way of doing it.

According to Dr. Brody, the patent hinges on the pairs finding, through trial and error, that the compound lithium boric acid in DNA electrophoresis is the optimal solution for this process. -more-

Faster DNA separation -- 2 In electrophoresis, solutions conduct electric current necessary to separate negatively charged DNA molecules. DNA is put through jellylike gels, and smaller DNA molecules move more quickly than larger ones as the current passes through. The researchers found, after much experimentation, that lithium boric acid would be a better buffer solution for the process than current 30-year-old methods.

A process that normally takes around one and a half, two hours to do can be done in 10 minutes in some instances it can be 10-fold faster, he explains.

A lot of our science is abstract and incremental, he notes
'"/>

Contact: Steve Benowitz
steven.benowitz@jefferson.edu
215-955-5291
Thomas Jefferson University
18-Jul-2007


Page: 1 2

Related biology news :

1. Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
2. Tiny genes may increase cancer susceptibility, Jefferson scientists find
3. Jefferson scientists use gene therapy to reverse heart failure in animals
4. Jefferson researchers discovery may change thinking on how viruses invade the brain
5. Jefferson scientists identify protein key to breast cancer spread, potential new drug target
6. Jefferson scientists find rabies-based vaccine could be effective against HIV
7. Jefferson scientists uncover gene mutation that cuts colon polyps, may suppress cancer
8. Targeting the adrenal gland could be key strategy against heart failure, Jefferson scientists show
9. Jefferson scientists find guardian genes choices crucial to stopping cancer process
10. Jefferson researchers uncover new way nature turns genes on and off
11. Jefferson researchers develop combined procedure for uterine preservation in treating fibroids

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
(Date:4/11/2017)... , April 11, 2017 Crossmatch®, a ... authentication solutions, today announced that it has been ... Research Projects Activity (IARPA) to develop next-generation Presentation ... "Innovation has been a driving force ... program will allow us to innovate and develop ...
(Date:4/5/2017)... , April 5, 2017  The Allen Institute ... Allen Cell Explorer: a one-of-a-kind portal and dynamic digital ... 3D imaging data, the first application of deep learning ... human stem cell lines and a growing suite of ... platform for these and future publicly available resources created ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia ... be hosting a Webinar titled, “Pathology is going digital. Is your lab ready?” ... pathology adoption best practices and how Proscia improves lab economics and realizes an ...
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , ... of Cancer Research, London (ICR) and ... with SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple ... as MUK nine . The University of ... is partly funded by Myeloma UK, and ICR will perform ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... maternal age to IVF success. , After comparing the results from the fresh ...
(Date:10/10/2017)... SAN DIEGO, CALIF. (PRWEB) , ... October 10, 2017 , ... ... website as part of its corporate rebranding initiative announced today. The bold new ... broaden its reach, as the company moves into a significant growth period. , It ...
Breaking Biology Technology:
Cached News: