HOME >> BIOLOGY >> NEWS
'Junk' DNA now looks like powerful regulator, Stanford researcher finds

STANFORD, Calif. -- Large swaths of garbled human DNA once dismissed as junk appear to contain some valuable sections, according to a new study by researchers at the Stanford University School of Medicine and the University of California-Santa Cruz. The scientists propose that this redeemed DNA plays a role in controlling when genes turn on and off.

Gill Bejerano, PhD, assistant professor of developmental biology and of computer science at Stanford, found more than 10,000 nearly identical genetic snippets dotting the human chromosomes. Many of those snippets were located in gene-free chromosomal expanses once described by geneticists as "gene deserts." These sections are, in fact, so clogged with useful DNA bits - including the ones Bejerano and his colleagues describe - that they've been renamed "regulatory jungles."

"It's funny how quickly the field is now evolving," Bejerano said. His work picking out these snippets and describing why they might exist will be published in the April 23 advance online issue of the Proceedings of the National Academy of Sciences.

It turns out that most of the segments described in the research paper cluster near genes that play a carefully orchestrated role during an animal's first few weeks after conception. Bejerano and his colleagues think that these sequences help in the intricate choreography of when and where those genes flip on as the animal lays out its body plan. In particular, the group found the sequences to be especially abundant near genes that help cells stick together. These genes play a crucial role early in an animal's life, helping cells migrate to the correct location or form into organs and tissues of the correct shape.

The 10,402 sequences studied by Bejerano, along with David Haussler, PhD, professor of biomolecular engineering at UC-Santa Cruz, are remnants of unusual DNA pieces called transposons that duplicate themselves and hop around the genome. "We used to think
'"/>

Contact: Krista Conger
650-725-5371
Stanford University Medical Center
23-Apr-2007


Page: 1 2

Related biology news :

1. Junk DNA may be very valuable to embryos
2. Study looks at ways to mitigate air pollution from freight transportation along I-95
3. Proteomics symposium looks at pediatric applications
4. Researcher looks for more targeted way to deliver cancer drugs
5. MERIS/AATSR Workshop looks at twin sensors with many uses
6. University looks to the past in fight against disease
7. New collision looks imminent for B-15A iceberg
8. Stegosaur plates and spikes for looks only, researchers say
9. International gathering of scientists looks toward future of cancer research
10. New book looks at ecosystem of mucous membranes
11. McGill researcher looks at the genetics behind cheese

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2020)... SAN FRANCISCO (PRWEB) , ... August 06, 2020 ... ... the life sciences industry, is pleased to announce that Eric Chen and Jessica ... Vice President of Product Management & Strategy, respectively. , Eric Chen heads development ...
(Date:7/31/2020)... SAN FRANCISCO (PRWEB) , ... July 30, 2020 ... ... Therapeutics’ maturing prescription digital therapeutics product portfolio with a near term focus on ... diverse biotech and pharma commercialization experience across multiple therapeutic areas and classes. As ...
(Date:7/10/2020)... ... July 09, 2020 , ... Today CJ BIO announced the first ... insight on the “fifth taste” phenomenon that is revolutionizing ingredient mixes, nutritional content and ... be live on Monday, July 13, 2020 at11:00 AM (CDT) during SHIFT20, the virtual ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been ... webinar will cover the history of eSource, the reasons it did not take off ... wearables, to site source, the industry is moving towards capturing data electronically for clinical ...
(Date:7/18/2020)... ... 16, 2020 , ... After research model surgery and catheter implantation, the long ... only the beginning of a successful study, while protecting and accessing the catheter or ... Head of Surgery from Envigo in a live webinar on ...
(Date:7/10/2020)... ... July 08, 2020 , ... ... a significant expansion of laboratory operations through its COVID-19 testing service, Bode-CARES ... programs. , Bode-CARES provides a turnkey solution that includes a ...
(Date:7/7/2020)... ... 06, 2020 , ... R3 International is now offering stem cell therapy for ... cells. Depending on the patient's condition, treatment may be offered IV, intrathecal or with ... form of Alzheimers dementia, and the incidence continues to increase as individuals live longer. ...
Breaking Biology Technology:
Cached News: