HOME >> BIOLOGY >> NEWS
K-State professor developing new strategies for delivery of drugs to fight, treat tuberculosis

MANHATTAN, KAN. -- It has been identified by the World Health Organization as the most dangerous infectious disease, causing more deaths -- more than 2 million a year -- than any other single infection. Approximately one-third of the world's population is already infected.

"It" is Mycobacterium tuberculosis.

A Kansas State University chemistry professor is seeking to stem the tide in the war against TB. According to the WHO, no new antituberculosis drugs have been marketed during the last 30 years. As such, new strategies are needed to lead to the successful development of antituberculosis therapies.

K-State's Stefan H. Bossmann is researching a new strategy for treatment of the deadly infectious disease using ruthenium-polypyridyl-complexes as antimycobacterial drugs.

Bossmann's research explores unique physical and chemical properties of channel proteins called porins, isolated from Mycobacterium smegmatis and Mycobacterium tuberculosis. He is attempting to understand the working principles of porin channels in natural and artificial environments and he hopes to eventually develop supramolecular model systems to serve as physical models for the biological function of the porin systems.

Bossmann will discuss his research at the American Chemical Society's national meeting and exposition, Aug. 28 - Sept. 1, in Washington, D.C. He will give an oral presentation at the conference Tuesday, Aug. 30.

"We have more and more resistant strains developing in Asia and Russia. We're also getting a large number of patients infected with TB immigrating to the United States," Bossmann said.

According to Bossmann, not many antibiotics actually work in treating TB because the disease has been steadily developing resistance to them. This makes new strategies for the delivery of drugs urgently needed, he said.

"It will become extremely difficult to treat cases of TB, in say 10 to 20 years down the road, because new treat
'"/>

Contact: Stefan H. Bossmann
sbossmann@k-state.edu
785-532-6817
Kansas State University
30-Aug-2005


Page: 1 2

Related biology news :

1. K-State biochemist contributes to article in Science magazine
2. K-State biologist hopes mosquito can break viral chain
3. K-State to collaborate on research to forecast ecological consequences of environmental changes
4. K-Staters design and build a low-cost remote sensing tool for environmental studies
5. K-State researchers study gene regulation in insects
6. K-State researchers study insects immune system
7. K-State eye researchers focus on stopping spread of damaged eye cells
8. K-State professors discover enzyme responsible for creation of a beetles hard shell
9. K-State part of effort to completely sequence common wheat genome
10. K-State professor studies how landscape dynamics affect extinction risk for migratory songbirds
11. K-State professor to discuss feeding the worlds population without poison

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... ... Commercial launch readiness is a critical stage in a product life cycle. While the ... economic downturn will only increase price pressures overall for the industry. The era of ... every product launch is critical. However, history shows that only a third of product ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... a publication detailing the use of its revolutionary NEXTGENPCR endpoint thermocycler to ... in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR protocol for the ...
(Date:6/25/2020)... (PRWEB) , ... June 24, 2020 , ... ... cloud-based enterprise software and software-driven clinical data services that accelerate drug development, is ... low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine ... the most prestigious ranking of the nation’s fastest-growing private companies. The list represents ... dynamic segment—its independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many ...
(Date:8/3/2020)... ... August 03, 2020 , ... ERT, ... and CEO has been named one of the 100 most inspiring individuals in ... 100 honorees are selected based on how they have inspired their colleagues and ...
(Date:7/31/2020)... ... 2020 , ... Anomet Products has introduced new custom composite ... with CRM, neurostimulation, vascular, and related devices. , Anomet Medical Clad Wire ... and cost criteria; especially where solid wire is limited. Typical configurations for implantable ...
(Date:7/22/2020)... ... July 22, 2020 , ... Join experts from Reed Tech , ... Solutions, in a one hour live webinar on Thursday, August 13, 2020 ... for drugs and medical devices. Specifically, for medical devices, the NMPA has departments dealing ...
Breaking Biology Technology:
Cached News: