HOME >> BIOLOGY >> NEWS
Latest data shows MabThera provides significant, sustained relief from symptoms of RA

Barcelona, Spain. New data presented at the EULAR meeting (European League Against Rheumatism) demonstrate that MabThera's (rituximab) effectiveness in relieving patients of the distressing symptoms of rheumatoid arthritis (RA) is sustained or further improved with subsequent courses of treatment, as is the number of patients achieving remission1. Importantly, the safety profile of MabThera remained unchanged in patients who had received as many as seven courses of treatment at 6-12 month intervals.

Commenting on the findings, Professor Keystone, Rheumatology Department at the University of Toronto, Canada, said: "As physicians gain experience with MabThera and the long-term efficacy and safety data are collected, we are able to make treatment decisions with confidence for the ultimate benefit of our patients."

Results following subsequent courses of therapy

A total of 1053 RA patients was treated with MabThera with almost 70% of patients followed up for more than two years and 11% for more than three years. The study was conducted in patients who had an inadequate response to treatment with either tumour necrosis factor (TNF) inhibitors or disease-modifying anti-rheumatic drugs (DMARDs), both of which are commonly used classes of RA drugs. All study patients received multiple courses of MabThera (2 x1000mg infusion, 2 weeks apart) based on disease activity.

The data showed that after three courses of MabThera in patients who had an inadequate response to TNF inhibitors:

  • The number of patients achieving the hard-to-reach goal of a 70% improvement in disease signs and symptoms (ACR70 response2) almost tripled from 11% to 25%

  • The number of patients achieving remission improved from 6% to 12%

Equally, in patients with an inadequate response or intolerance to DMARDs, the remission rate increased almost threefold from 5% to 14% confirming the benefit of providing subsequen
'"/>

Contact: Lynn Huynh
lynn_huynh@uk.cohnwolfe.com
44-207-331-5332
Cohn & Wolfe, London
13-Jun-2007


Page: 1 2

Related biology news :

1. Latest strategies for moving research toward a cure for diabetes explored at global scientific forum
2. Latest plant health research to be presented in San Diego
3. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
4. Latest buzz: Marijuana may slow progression of Alzheimers disease
5. Latest enhancements to the free Access Grid Toolkit are now available for download
6. Slow-frozen people? Latest research supports possibility of cryopreservation
7. Latest plant disease research to be presented in Quebec City
8. Latest study: Scientists say no evidence exists that therapod dinosaurs evolved into birds
9. Latest gene therapy research to be presented in St. Louis, June 1-5, 2005
10. Latest census finds more American pika populations disappear as climate warms
11. Latest buzz in research: Intoxicated honey bees may clue scientists into drunken human behavior

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... May 16, 2017   Bridge Patient Portal ... and MD EMR Systems , an electronic ... for GE, have established a partnership to build ... and the GE Centricity™ products, including Centricity Practice ... These new integrations will allow healthcare ...
(Date:4/18/2017)... , April 18, 2017  Socionext Inc., a global expert in ... media edge server, the M820, which features the company,s hybrid codec ... provided by Tera Probe, Inc., will be showcased during the upcoming ... NAB show at the Las Vegas Convention ... Click ...
(Date:4/11/2017)... BEACH GARDENS, Fla. , April 11, 2017 ... identity management and secure authentication solutions, today announced ... contract by Intelligence Advanced Research Projects Activity (IARPA) ... for IARPA,s Thor program. "Innovation has ... onset and IARPA,s Thor program will allow us ...
Breaking Biology News(10 mins):
(Date:6/20/2017)... ... June 20, 2017 , ... National ... well-versed leader with extensive assay development and biomarker expertise, as VP of Scientific ... Boston CRO specializing in bio-analytical assay development and sample testing services. The organization ...
(Date:6/20/2017)... San Francisco, CA (PRWEB) , ... June 20, ... ... with patented technology for discovery of antibody therapeutics from millions-diverse immune repertoires, announces ... International Conference in San Diego, California. Dave Johnson, PhD, CEO of GigaGen, will ...
(Date:6/19/2017)... ... 19, 2017 , ... EDETEK, Inc., a clinical technology company ... launching two new additions of its award-winning cloud-based platform CONFORM™: Information Hub and ... 2017 Annual Meeting in Chicago, IL, June 19-22, 2017. , “Modern clinical trials ...
(Date:6/19/2017)... Ames, Iowa (PRWEB) , ... June 19, 2017 , ... ... and interplay among its cells and tissues by delivering pollen and nectar containing nutrients ... and the means to stay healthy. , Many recent indicators point to a decline ...
Breaking Biology Technology:
Cached News: