HOME >> BIOLOGY >> NEWS
Learning to fight an adversary that won't stay down

New biomolecular technologies have largely failed to deliver the hoped-for knockout punch breakthrough against the defences of disease-causing bacteria, says a leading Canadian specialist in antibiotic resistance.

Techniques such as genomic sequencing and high throughput screening were expected to make the development of new antibiotic compounds easier and more productive. But in most cases the microbes continue to hold the upper hand and if three billion years of bacterial history is any kind of track record, we're in for an endless running battle, says Dr. Julian Davies, a microbiologist at the University of British Columbia.

"We haven't evolved in our thinking sufficiently to be able to match the microbes," says Dr. Davies, Scientific Director of the Canadian Bacterial Diseases Network. "Pharmaceutical companies and other researchers have put hundreds of millions of dollars into 'modern' approaches to antibiotic discovery over the past six or seven years and this has failed miserably."

The scientist, whose work is supported by Science and Engineering Research Canada (NSERC), has organized a symposium on the evolutionary genetics of antibiotic resistance at the 2005 meeting of the American Association for the Advancement of Science in Washington D.C.

The ongoing appearance of new pathogen varieties like multi-resistant E. coli and Staphylococcus aureus (MRSA), the bacterium that causes methicillin-resistant tuberculosis, provide good examples of the challenges we face, says Dr. Davies.

Ironically, he says, advances in molecular biology techniques have shown just how adept these pathogens are at adapting to anything we can throw at them. Innovations such as highly efficient polymerase chain reaction (PCR) have made it possible to identify and study the many genes responsible for antibiotic resistance in hospitals and the environment.

"What has been found is that there are more antibiotic resistance genes around than
'"/>

Contact: Dr. Julian Davies
julian.davies@ubc.ca
604-822-5856
Natural Sciences and Engineering Research Council
20-Feb-2005


Page: 1 2

Related biology news :

1. Learning to evolve: With a little help from my ancestors
2. Learning a second language -- Is it all in your head?
3. Protein pulling -- Learning how proteins fold by pulling them apart
4. Learning how to help migrating swans find forage
5. Learning during sleep?
6. Learning how nature splits water
7. Learning global solutions to local problems
8. Learning to live with oxygen on early Earth
9. Learning the lessons of the worlds oldest ecological experiment
10. Learning the language of DNA
11. SNM Lifelong Learning and Self-Assessment program modules approved by ABNM, ABR for CME credit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... 24, 2017 Janice Kephart , ... Identity Strategy Partners, LLP (IdSP) , today issues ... President Trump,s March 6, 2017 Executive Order: ... vetting can be instilled with greater confidence, enabling ... all refugee applications are suspended by until at ...
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... 2017 No two people are believed ... New York University Tandon School of Engineering and ... that partial similarities between prints are common enough ... phones and other electronic devices can be more ... lies in the fact that fingerprint-based authentication systems ...
Breaking Biology News(10 mins):
(Date:5/29/2017)... ... May 29, 2017 , ... ... of the Year by the International Business Innovation Association and the Milken Institute ... accolades underscore what business leaders in and out of Greater Gainesville already know: ...
(Date:5/26/2017)... ... May 25, 2017 , ... Studying biological ... each occurrence. Live cell imaging using fluorescence microscopy is the perfect approach to ... fluorescence microscopy methods will be discussed, from small animal models and tissues to ...
(Date:5/24/2017)... Utah (PRWEB) , ... May 24, 2017 , ... ... the selection and implementation of CLEARAS Water Recovery’s Advanced Biological Nutrient Recovery (ABNR™) ... key component of a $24 million plant upgrade to sustainably meet current and ...
(Date:5/24/2017)... ... May 24, 2017 , ... Patient Monitoring and Diagnostic ... connectivity to reduce the amount of wiring in a healthcare facility and allow ... devices including infusion pumps, heart and hypertension monitoring, glucose monitoring, and other wearable ...
Breaking Biology Technology:
Cached News: