HOME >> BIOLOGY >> NEWS
Link suggested between regions on two chromosomes and bipolar disorder

Boston, MA--An international team of 53 researchers has offered the most convincing evidence so far linking bipolar disorder, also known as manic depression, to two chromosomal regions in the human genome. The finding gives scientists refined targets for further gene studies.

"Even though bipolar disorder affects millions of people around the world--sometimes throughout their lifetimes--what we understand to be biologically relevant at the genetic level is not terribly characterized," said Matthew McQueen, lead author and postdoctoral fellow in the Department of Epidemiology at the Harvard School of Public Health (HSPH). "This research can help focus the field to identify viable candidate genes."

The study will appear in the October issue of the American Journal of Human Genetics and is available now in the journal's electronic edition online at http://www.journals.uchicago.edu/AJHG/journal/contents/v77n4.html.

More than two million American adults have bipolar disorder, according to the National Institute of Mental Health. Patients typically experience dramatic mood swings from episodes of euphoria and high energy to feelings of intense sadness, fatigue, and even suicide. Psychiatrists have identified two primary forms of the illness: bipolar I disorder, which is the classic form of recurring mania and depression, and bipolar II disorder, which has less severe episodes of mania. Treatment often includes medication.

The exact cause of the illness remains unknown, but scientists suspect the involvement of several genes, coupled with environmental influences. A number of individual studies have suggested genomic regions linked to bipolar disorder, but their results have been inconsistent and difficult to replicate, leaving the field "standing at a crossroads, wondering in which direction to go next," said McQueen.

To establish more definitive researc
'"/>

Contact: Christina Roache
croache@hsph.harvard.edu
617-432-6052
Harvard School of Public Health
15-Sep-2005


Page: 1 2

Related biology news :

1. Fragile X-related disorder difficult to diagnose; guidelines suggested in new study
2. New class of tuberculosis-fighting antibiotics suggested by biochemical-pathway study
3. Common lineage suggested for viruses that infect hosts from all three domains of life
4. New textbook illuminates the close links between evolutionary and molecular biology
5. Link between sunspots, rain helps predict disease in east Africa
6. Link identified between Alzheimers disease and glaucoma
7. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
8. Human knowledge is based upon directed connectivity between brain areas
9. First case of successful ovarian tissue transplantation between two, nonidentical sisters
10. Strength of connections between brain regions may affect an adolescents response to peer influence
11. MIT IDs link between brain tumor proteins

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/29/2020)... ... January 29, 2020 , ... Jason ... and Data Sciences practice, providing consulting services for strategy, research and development and ... Mike Townley, co-founder and Managing Partner of CREO, an innovative management consulting and ...
(Date:1/28/2020)... (PRWEB) , ... January 28, 2020 , ... ... life sciences companies and government agencies, announced that the firm has established a ... country. Tunnell’s Cambridge office will be in the Cambridge Innovation Center (CIC), at ...
(Date:1/27/2020)... ... January 27, 2020 , ... Cytonus Therapeutics Inc. today ... tech entrepreneur, and former senior management consultant at McKinsey & Company who holds ... alternative investment firm. , “Chris Thorne has exceptional business acumen with a ...
Breaking Biology News(10 mins):
(Date:2/3/2020)... ... February 03, 2020 , ... ... MA, announce that OmniType, the 11-locus, single tube multiplex successor to Holotype HLA ... best-in-class product featuring locus-multiplexing and short library preparation, for HLA genotyping from sample ...
(Date:1/28/2020)... (PRWEB) , ... January 28, ... ... of enterprise software solutions for biopharmaceutical R&D, today announced the release of ... reinforces Genedata’s focus on supporting the implementation of Multi-Attribute Methods (MAM) for ...
(Date:1/27/2020)... ... January 27, 2020 , ... Cerebyte, the leader in “instant ... today announced the availability of neuroscience of transformational leadership workshops. These highly interactive, ... of leadership and change research to become great transformational leaders. The workshops ...
(Date:1/24/2020)... ... January 24, 2020 , ... The plastic and reconstructive surgeons at ... New Jersey epitomize the notion that plastic surgery is much more than just cosmetic ... media. , Over the last 20 years NJ Top Docs, Dr. Andrew Elkwood, Dr. ...
Breaking Biology Technology:
Cached News: