The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
Link suggested between regions on two chromosomes and bipolar disorder

h, McQueen and his colleagues did something unusual. They secured and then combined original genome scan data from 11 independent linkage studies, instead of relying on the more common approach of using summary data from such studies.

"The use of original data made a significant difference in our ability to control for variation in several factors among the different data sets and to make the overall analysis much more consistent and powerful," said Nan Laird, HSPH Professor of Biostatistics and senior author on the paper.

The resulting analysis involved 1,067 families and 5,179 individuals from North America, Italy, Germany, Portugal, the UK, Ireland, and Israel, who had provided blood samples and family medical histories. The research team combined the data into a single genome scan and found strong genetic signals on chromosomes 6 and 8. The team now hopes to narrow the search to find associations between specific genes and the mental illness.

The analysis was funded through the Study of Genetic Determinants of Bipolar Disorder Project at the National Institute of Mental Health. Other researchers on the analysis team represented Massachusetts General Hospital, The Broad Institute, and the University of Pittsburgh.


'"/>

Contact: Christina Roache
croache@hsph.harvard.edu
617-432-6052
Harvard School of Public Health
15-Sep-2005


Page: 1 2

Related biology news :

1. Fragile X-related disorder difficult to diagnose; guidelines suggested in new study
2. New class of tuberculosis-fighting antibiotics suggested by biochemical-pathway study
3. Common lineage suggested for viruses that infect hosts from all three domains of life
4. New textbook illuminates the close links between evolutionary and molecular biology
5. Link between sunspots, rain helps predict disease in east Africa
6. Link identified between Alzheimers disease and glaucoma
7. Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
8. Human knowledge is based upon directed connectivity between brain areas
9. First case of successful ovarian tissue transplantation between two, nonidentical sisters
10. Strength of connections between brain regions may affect an adolescents response to peer influence
11. MIT IDs link between brain tumor proteins

Post Your Comments:
(Date:11/25/2009)...you eat may be just as vital to your health as wha... for Biological Studies. Their experiments in mice...sands of genes in the liverthe body,s metabolic cl... not by the body,s circadian clock as conventional...he activity of a large number of genes completely ...
(Date:11/24/2009)...pening new doors to understanding how sounds assoc...a marine mammal or if they hear it at all. , Th...rs that NASA uses to detect flaws in the space shu... scientists to peek inside the giant head of a wha...onal replicas of a whale,s hearing anatomy using a...
(Date:11/24/2009)...tion of a remarkable class of ring-shaped protein ...Lawrence Berkeley National Laboratory (Berkeley La...y beamline at the Advanced Light Source (ALS). The...ssion and replication, and are vital to the surviv...agents, such as the human papillomavirus, which ha...
Breaking Biology News(10 mins):Feeding the clock 2Feeding the clock 3Rocket science leads to new whale discovery 2Atomic-level snapshot catches protein motor in action 2Atomic-level snapshot catches protein motor in action 3Atomic-level snapshot catches protein motor in action 4Dilon Diagnostics Joins Forces With Philips for Womens Health Solutions 5368 1Dilon Diagnostics Joins Forces With Philips for Womens Health Solutions 5368 2Dilon Diagnostics Joins Forces With Philips for Womens Health Solutions 5368 317th International Process Development Conference to Feature Presentations on Safety Process Development Crystallization PAT Scale Up and Producti 14423 117th International Process Development Conference to Feature Presentations on Safety Process Development Crystallization PAT Scale Up and Producti 14423 2Is London Heading For a Water Crunch 3F 59261 1Is London Heading For a Water Crunch 3F 59261 2Is London Heading For a Water Crunch 3F 59261 3Is London Heading For a Water Crunch 3F 59261 4
(Date:11/24/2009)...v.24/PRNewswire-Asia/--ShanghaiBiolaxyannouncedthe...pprovedthe,investigationalnewdrugapplication(IND)f...informulationtotreatdiabetes.ThisIND,approvalallow..., Diabetesisadisordercharacteristicofhighbloodgl...oftenresultinseveremicro-and,macro-vasculardisease...
(Date:11/24/2009)...cacyendpointhasbeenmetforpatientswithadvanced-stag...Nov.24/PRNewswire-FirstCall/-AEternaZentarisInc.(N...maceuticalcompanyfocusedonendocrinetherapyandoncol...tudywithitstargetedcytotoxicpeptideconjugate,AEZS-...entendometrialcancer.Inapersonalizedhealthcareappr...
(Date:11/24/2009)...v.24,2009/PRNewswire-FirstCall/--ArenaPharmaceutic...anyisscheduledtopresentatthePiperJaffray21stAnnual...ternTime(8:30a.m.PacificTime)attheNewYorkPalaceHot...fExecutiveOfficer,isscheduledtoprovideanoverviewof...veryprograms. ,, Aliveaudiowebcastofthepresenta...
(Date:11/24/2009)... Program Connects Customers with Partners Va...ith DNA Genotek Products , ...otek , a leading provider of products for biologic...n, today announced its new global partner program....NA Genotek,s partner community and is designed to ...
Breaking Biology Technology:Biolaxy Secures IND Approval for Oral Insulin 2AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 2AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 3AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer 4Arena Pharmaceuticals to Present at the Piper Jaffray 21st Annual Health Care Conference 2DNA Genotek Launches Global Partner Program 2DNA Genotek Launches Global Partner Program 3
Other News:
...ESDA, Md. (May 18, 2005) In this obesity-obsessed...t tastes good enough to be a condiment or flavorin...onsider hydroxycitric acid (HCA), known variously ...d in Indian and Thai food as a condiment and flavo...
...he American Psychiatric Association's (APA) annual...ute of Mental Health (NIMH) will showcase advances...oved treatments for mental disorders. Under the t...al Care," this research track will spotlight NIMH'...
...ON, May 19 Research from the Republic of Korea's ... edition of Science represents a major advance in ...aused by human disease and injury, according to Ge...research development in the department of obstetri...
...ing the door to a new way of understanding ocean p...ces, a group of researchers at Scripps Institution...San Diego, has developed a groundbreaking analysis...es can unfold across its waters....The study, publ...
Hydroxycitric acid slows glucose uptake, cuts insulin peaks/valleys a la South Beach Diet 2Hydroxycitric acid slows glucose uptake, cuts insulin peaks/valleys a la South Beach Diet 3NIMH research showcased at APA meeting 2Research marks giant step in potential of using stem cells to treat human disorders 2Research marks giant step in potential of using stem cells to treat human disorders 3Scripps scientists find potential for catastrophic shifts in Pacific ecosystems 2Scripps scientists find potential for catastrophic shifts in Pacific ecosystems 3
BOSTON Researchers at Dana-Farber Cancer Institute have made a discovery that could help solve a mystery in cancer biology: how a sunburn acquired during a childhood day at the beach can develop into
...shed in Genome Biology investigates genes that inc... gain a greater understanding of the ageing proces... California and Harvard Medical School screened 10...r results revealed that six populations of mutant ...
...se population-based study in this week's issue of ...take folic acid supplements during pregnancy do no...e birth.......Folic acid supplements are recommend... tube defects--such as spina bifida and anencephal...
... January 31, 2003 --Much like guided missiles that...ded to the fertilization site by temperature, repo...rrent issue of Nature Medicine.......The site wher...here the sperm make a pause in their journey throu...
Study sheds light on how the sun causes skin cancer 2Study sheds light on how the sun causes skin cancer 3Study sheds light on how the sun causes skin cancer 4Fruit flies unlock Methuselah's secrets 2Sperm use heat sensors to find the egg 2Sperm use heat sensors to find the egg 3