HOME >> BIOLOGY >> NEWS
Looking for new approaches to target antibiotic-resistant bacteria

Infection with Entercoccus faecalis can cause bacterial endocarditis, an infection of the heart valves that if not treated with antibiotics results in death. The number of infections with antibiotic-resistant E. faecalis is increasing. So, researchers are looking for alternative strategies for treating individuals who become infected with this bacterium. Now, in a study appearing in the October issue of the Journal of Clinical Investigation, researchers from University of Texas Medical School at Houston have identified proteins that are required for E. faecalis to cause endocarditis in rats and that might make good vaccine candidates.

Barbara Murray and colleagues found that E. faecalis expresses four proteins that are required for the bacteria to form protein structures on their surface known as pili. The pili were required for the bacteria to aggregate and form biofilms. More importantly, rats infected with E. faecalis lacking expression of any one of these proteins suffered less severe bacterial endocarditis. This study, identifying E. faecalis proteins required for the bacterium to cause endocarditis in rats, might lead to the development of new strategies to treat individuals who become infected with E. faecalis.

In an accompanying commentary, Jonathan Budzik and Olaf Schneewind from the University of Chicago agree with this suggestion when they comment that, "This information may enable new vaccine strategies for the prevention of E. faecalis infections."


'"/>

Contact: Karen Honey
212-342-4159
Journal of Clinical Investigation
2-Oct-2006


Page: 1

Related biology news :

1. Looking for life on Jupiters icy moon Europa
2. Looking to a new era in bee research
3. Looking for consensus on how to manage metastatic breast cancer
4. Cold case: Looking for life on Mars
5. Looking at Eyeless from two directions
6. Hydrology, Politics, and Katrina: Looking Backward, and Going Forward
7. Looking for the genes that affect a persons level of response to alcohol
8. Looking at autoimmune diabetes, literally
9. New approaches to endometriosis treatment -- mouse experiments point the way
10. New understanding of schizophrenia could lead to new treatment approaches
11. Novel approaches to tackling obesity, cancer and MRSA

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/2/2016)... , June 2, 2016   The Weather Company ... announcing Watson Ads, an industry-first capability in which consumers will ... being able to ask questions via voice or text and ... Marketers have long sought an ... consumer, that can be personal, relevant and valuable; and can ...
(Date:5/24/2016)... -- Ampronix facilitates superior patient care by providing unparalleled technology to leaders of the ... latest premium product recently added to the range of products distributed by Ampronix. ... ... ... Display- Ampronix News ...
(Date:5/12/2016)... WearablesResearch.com , a brand of Troubadour Research & ... Q1 wave of its quarterly wearables survey. A particular ... a program where they would receive discounts for sharing ... "We were surprised to see that so many ... CEO of Troubadour Research, "primarily because there are segments ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... the release of its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” ... and retention in this eBook by providing practical tips, tools, and strategies for ...
(Date:6/23/2016)... June 23, 2016 Houston Methodist Willowbrook ... Cy-Fair Sports Association to serve as their official ... Houston Methodist Willowbrook will provide sponsorship support, athletic ... with association coaches, volunteers, athletes and families. ... Cy-Fair Sports Association and to bring Houston Methodist ...
(Date:6/23/2016)... ... 23, 2016 , ... Supplyframe, the Industry Network for electronics ... Lab . Located in Pasadena, Calif., the Design Lab’s mission is to bring ... designed, built and brought to market. , The Design Lab is Supplyframe’s physical ...
(Date:6/23/2016)... June 23, 2016 ... 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 Published recently ... peer-reviewed journal from touchONCOLOGY, Andrew D Zelenetz ... of cancer care is placing an increasing burden ... expensive biologic therapies. With the patents on many ...
Breaking Biology Technology:
Cached News: