HOME >> BIOLOGY >> NEWS
Losartan prevents life-threatening insulin resistance in burn injuries

SAN FRANCISCO Researchers have found a way to prevent insulin resistance in burn-injured rats, a finding that, while still quite preliminary, could eventually save burn victims' lives and speed their recovery.

The researchers honed in on the renin-angiotensin system (RAS) as the key to preventing insulin resistance -- a unique line of inquiry in burn research, according to lead author Sherry O. Kasper. About 70% of serious burn victims develop insulin resistance, a condition marked by elevated levels of glucose and insulin.

Reversing the condition has the potential to reduce mortality, length of stay in intensive care and infection rates among severe burn patients, Kasper said. The American Physiological Society (APS) awarded Kasper a Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award in recognition of the exemplary research. Kasper also received the Mead Johnson Research Award in Endocrinology and Metabolism for the best abstract in endocrinology and metabolism by a graduate student, resident or postdoctoral fellow.

*Paper presentation: "Thermal injury induced insulin resistance is associated with the renin-angiotensin system (RAS)" 12:45 p.m.-3 p.m. Wednesday, April 5, Metabolism During Stress and Trauma 928.2/board #D407. On view 7:30 a.m. 3:30 p.m. Research was by Sherry O. Kasper, Scott M. Castle, Brian J. Daley, Blaine L. Enderson, Michael D. Karlstad, University of Tennessee Graduate School of Medicine, Knoxville, TN.

Drug blocks RAS

Insulin resistance occurs when the body senses glucose overload and attempts to reduce it by producing more insulin. When the additional insulin is unable to moderate the glucose, the body releases even more insulin. The result: elevated levels of both glucose and insulin. Burn-related insulin resistance can last for months, Kasper said.

Kasper became interested in RAS while studying the system as it relates to diabetes, blood pressure and aging. Karlstad,
'"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
6-Apr-2006


Page: 1 2 3

Related biology news :

1. Critical protein prevents DNA damage from persisting through generations
2. Repair of DNA by Brca2 gene prevents medulloblastoma
3. Vaccine prevents prion disease in mice
4. New compound prevents alcoholic behavior, relapse in animals by blocking stress response
5. Cold Spring Harbor Laboratory scientists discover new gene that prevents multiple types of cancer
6. Antibody therapy prevents type 1 diabetes in mice
7. Cambridge led team discovers gene mutation which prevents carriers from feeling pain
8. The abortion pill compound prevents breast tumor growth
9. Vaccination with embryonic stem cells prevents lung cancer in mice
10. Turmeric prevents experimental rheumatoid arthritis, bone loss, University of Arizona study shows
11. Early treatment prevents lasting breathing problems in some premature babies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... Emtec, Inc.®, ... deliver a joint presentation with Versiti’s CIO at the Healthcare Industry User ... Shingle Creek Resort. , Versiti Vice President and Chief Information Officer, Lynne Briggs, ...
(Date:6/13/2019)... ... 13, 2019 , ... KICVentures announced today its plans to host ... Pain Management-Driven ASC Conference in Chicago on Thursday, June 13th at 6:30 pm. The ... IL in the 3rd floor Ticino Hospitality room in space #74T. , The event ...
(Date:6/11/2019)... ... June 12, 2019 , ... With a rapidly growing customer ... the Geneious Biologics platform as a premium hub for bioinformatics and computer programming ... “The Geneious team has done an excellent job accommodating our specific data, resulting ...
Breaking Biology News(10 mins):
(Date:5/22/2019)... ... May 22, 2019 , ... Artemis (formerly Agrilyst), ... million Series A funding round co-led by Astanor Ventures and Talis ... Fund and iSelect Fund . The company has raised $11.75m to date ...
(Date:5/14/2019)... ... May 13, 2019 , ... Leak Detection ... for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is excited to ... aims to improve LDA’s ability to communicate directly with the marketplace; serving as ...
(Date:5/4/2019)... ... May 03, 2019 , ... More than three thousand people ... the scientist and ufologist Urandir Fernandes de Oliveira, last Thursday (25), during the ... of some research carried out by the association, in partnership with scientists from ...
(Date:5/2/2019)... ... ... Stay on top of current hot topics through free webinars presented by ... is free, so be sure to register today to save your place! Participate in ... see our upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology Clinical Trials ...
Breaking Biology Technology:
Cached News: