HOME >> BIOLOGY >> NEWS
MIT bioengineer advances survival, promise of adult stem cells

CAMBRIDGE, Mass.--MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells.

Adult stem cells, found in many tissues in the body, are precursor cells for specific cell types. For example, stem cells found in the bone marrow develop into blood cells, bone cells and other connective tissues, and neural stem cells develop into brain tissue.

Those stem cells hold great promise for treatment of injuries and some diseases, says MIT professor of biological engineering Linda Griffith.

Griffith is the senior author of a recent study showing that when presented in the right physical context, certain growth factors encourage the survival and proliferation of bone marrow mesenchymal stem cells grown outside of the body.

The work offers hope that one day, stem cells removed from a patient could be transplanted to an injury site and induced to grow into new, healthy tissue. The research appears in the January 18 online issue of Stem Cells.

Griffith's team focused on the potential for mesenchymal stem cells to grow into new bone in patients with bone cancer or severe bone injuries. Current treatment for such patients involves replacing the bone with either cadaver bone or, more commonly, a piece of the patient's hip bone.

Ideally, surgeons would like to be able to aspirate bone marrow from the hip, which is a much less painful and invasive process than removing bone, and transplant the stem cells from that marrow into the injury site.

Although patients' own marrow has been used successfully in certain situations, Griffith and her clinical collaborators believe that the inflammatory response following transplant may limit survival of cells under many clinical conditions.

To avoid that deadly response, Griffith and her team sought a way to manipulate the environment surrounding the cells
'"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
27-Feb-2007


Page: 1 2 3

Related biology news :

1. Boston Univeristy bioengineers devise dimmer swith to regulate gene expression in mammal cells
2. Clemson bioengineer gets national boost
3. Pancreas bioengineering at the MUHC receives funding boost
4. Rice bioengineers pioneer techniques for knee repair
5. Dartmouth, GlycoFi researchers make leap in protein bioengineering
6. Disease diagnosis, bioengineering covered at state nano summit
7. UCSD medical/bioengineering reseachers show titanium debris satobtage artificial joints
8. Study advances vCJD prion detection
9. New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
10. SNM advances professional definition for molecular imaging
11. New research advances energy efficiency, safety and performance of public transit

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/26/2020)... ... August 25, 2020 , ... ... novel pharmaceuticals targeting mitochondria, in partnership with Essex Bio-Technology, a bio-pharmaceutical company ... U.S. Phase 3 VISTA-2 study of SkQ1 ophthalmic solution in patients with ...
(Date:8/21/2020)... ... August 19, 2020 , ... “How can ... businesses dedicated to Salivary Bioscience for more than twenty years. Together with Douglas ... Springer, " Salivary Bioscience: Foundations of Interdisciplinary Saliva Research and Applications ," and ...
(Date:8/7/2020)... ... August 06, 2020 , ... Alucio™, a fast-growing provider ... Eric Chen and Jessica Wong have joined the company’s leadership team as Vice ... Eric Chen heads development efforts for Alucio’s flagship product, Beacon, an innovative cloud-based ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... July 17, 2020 , ... dicentra , a leading ... food industries, is pleased to announce that Charles Galea has joined its clinical ... Charles is an accomplished and results-driven sales executive with over 10 years of ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... (PTU) is commonly used to suppress pigment formation in zebrafish embryos, maintaining optical ... team led by Dr MA has been using the zebrafish model to investigate ...
(Date:7/7/2020)... ... July 06, 2020 , ... Bio-IT World has announced ... Bristol-Myers Squibb, the University of Chicago, Massachusetts General Hospital, Mission: Cure, and the ... awards program, highlighting outstanding examples of how technology innovations and strategic initiatives can ...
(Date:7/1/2020)... (PRWEB) , ... June 30, ... ... expert tissue data insights, today announced that the launch of a new ... along with data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is ...
Breaking Biology Technology:
Cached News: