HOME >> BIOLOGY >> NEWS
MIT device draws cells close -- but not too close -- together

CAMBRIDGE, Mass.--In a popular children's game participants stand as close as possible without touching. But on a microscopic level, coaxing cells to be very, very close without actually touching one another has been among the most frustrating challenges for cell biologists.

Now MIT researchers led by Sangeeta Bhatia, associate professor of electrical engineering and computer science at the Harvard-MIT Division of Health Sciences and Technology (HST) and Brigham and Women's Hospital, have solved the problem with a novel device. The work promises to allow researchers to perform cellular experiments that were previously impossible.

Bhatia and HST postdoctoral associate Elliot Hui describe the device in the March 27 online issue of the Proceedings of the National Academy of Sciences. Hui is first author of the paper.

The new device, a microelectromechanical system (MEMS), allows biologists to physically arrange cells to be either touching, close but not touching, or completely separated from one another. Further, they can change that configuration at will. And the device works without the use of tools such as the microscopes or robotic control arms typically required by MEMS devices.

Because cells communicate via signals transmitted both through the touching of cell membranes and through soluble molecules that flow between separated cells, biologists need to vary the spacing of cells to study their interactions. Also, since some signals induce a cell to change its internal programming, it is important for biologists to be able to rearrange cells over time to learn which signals spur change and which don't.

In the past, researchers erected chemical "moats" around cells in an attempt to keep them close but separate. Over time, however, cells invariably breech the divide. "They are very good at crossing the moat," said Bhatia, who performed several such experiments in graduate school.

Bhatia and Hui's first
'"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
29-Mar-2007


Page: 1 2 3

Related biology news :

1. Geisinger scientist seeks cure for Lou Gehrigs disease, creating device to find treatment
2. Brains hearing center may reorganize after implant of cochlear device
3. Lab-on-a-chip device from Berkeley Lab to speed proteomics research
4. Penn study finds ICD devices offer heart patients life-saving benefits
5. Research on microfluidics widens the possibilities for electronic devices
6. Microscopic sea creatures provide foundation for gas sensors and other devices
7. Breakthrough in nanodevice synthesis revolutionizes biological sensors
8. Ikerlan-IK4 and Gaiker-IK4 patent device for rapid diagnosis of infectious diseases and cancer
9. New miniaturized device for lab-on-a-chip separations
10. Professors to develop hand-held pathogen testing device
11. Nano-devices hold promise for early-stage cancer detection

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/13/2018)... ... November 12, 2018 , ... LabRoots, the ... will be hosting its 9th Annual Clinical Diagnostics & Research Virtual Event ... and updates in regulatory processes to ensure patient safety and proper practices. ...
(Date:11/9/2018)... ... November 09, 2018 , ... Controlled Contamination ... sales structure that will enable CCS to scale its business across the US ... a large geographic footprint and a need for a wide array of services ...
(Date:11/7/2018)... , ... November 07, 2018 , ... ... and the flexibility to adjust to last-minute changes all contribute to client retention ... The clinical trial patient travel and expense services provider says 80 percent of ...
Breaking Biology News(10 mins):
(Date:11/11/2018)... (PRWEB) , ... November 09, 2018 , ... Triple W, ... CES® 2019 Innovation Awards Honoree for DFree ®, the first health ... you when it’s time to go to the bathroom. The announcement was made during ...
(Date:11/7/2018)... ... November 07, 2018 , ... Since ... campaign to increase awareness of the adult tissue stem cell counting problem in ... November, the company is intensifying this effort with new educational publications and presentations ...
(Date:11/5/2018)... ... 05, 2018 , ... USARAD Holdings Inc., the leading US ... healthcare VC firms announces at Distributed Health 2018 conference November 5-6 (Nashville, TN) ... and obtaining its first radiology interpretations, one of the first known true use ...
(Date:11/3/2018)... N.C. (PRWEB) , ... November 01, 2018 , ... Triangle ... by Inc. Magazine as one of the fastest-growing private companies in the United States, ... Inc. 5000 list ranks private companies based on percentage revenue growth over the previous ...
Breaking Biology Technology:
Cached News: