HOME >> BIOLOGY >> NEWS
Major breakthrough in the treatment of cancers and infectious diseases

Montreal, August 24, 2005 Dr. Andr Veillette, a researcher at the Institut de recherches cliniques de Montral (IRCM), and his team will publish in the upcoming issue of the prestigious journal Nature Immunology of Nature Publishing Group, a discovery that could significantly advance the treatment of cancers and infectious diseases. Current treatments frequently achieve only limited results with these types of diseases, which affect hundreds of thousands of Canadians.

Dr. Veillette's team identified one of the basic mechanisms controlling NK ("natural killer") cell activity. Produced by the immune system, NK cells are responsible for recognizing and killing cancer cells and cells infected by viruses such as the viruses causing hepatitis and herpes. NK cell deficiency is associated with a higher frequency of cancers and serious infections. Dr. Veillette's breakthrough demonstrates that a molecule known as EAT-2, present in NK cells, suppresses its killer function. Inhibiting EAT-2 with medications could boost NK cell activity, helping to combat cancers and infections.

This publication constitutes a significant milestone for Dr. Veillette, an internationally renowned expert in the identification of the molecular mechanisms controlling the immune system. The article, which is slated for publication online on August 28 in Nature Immunology, gives genetic evidence for the inhibiting role of EAT-2 in NK cells. It is the product of over five years of intensive research by Dr. Veillette's team.

More specifically, by studying mice in which the EAT-2 protein is eliminated through genetic manipulations, Dr. Veillette's team has established that suppressing EAT-2 results in the production of NK cells that are much more effective at killing cancer cells. Inhibiting the function of EAT-2 with medications could therefore stimulate the killer function of NK cells, and increase their capacity to destroy cancer and virus-infected cells. These medications co
'"/>

Contact: Lucette Thriault
lucette.theriault@ircm.qc.ca
514-987-5535
Institut de recherches cliniques de Montreal
28-Aug-2005


Page: 1 2

Related biology news :

1. Major breakthrough in understanding how HIV interferes with infected cell division
2. Major study predicts grim future for Europes seas
3. Major genetic study identifies clearest link yet to obesity risk
4. Major gene study uncovers secrets of leukemia
5. Major society publisher announces support for public access to scientific literature
6. Major link in brain-obesity puzzle found
7. Major Wellcome Trust award to take science from the bench to the bedside
8. Major breakthrough in the mechanism of myelin formation
9. Major new osteoporosis study to recruit people in Orkney
10. Major genetic risk factor found for prostate cancer
11. Major report on tigers to be released Thursday at National Zoo

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/29/2018)... CAMBRIDGE, Mass. (PRWEB) , ... August 28, 2018 ... ... QipWorks, today introduced an annual awards program that recognizes women of excellence in ... recipient. , Sponsored by QipWorks, the Johanna Dwyer Women in IP Award aims ...
(Date:8/26/2018)... ... August 25, 2018 , ... ... of a biofield energy treated nutraceutical to reduce inflammation and autoimmune disorders and ... and blood, as well as inflammation. The following data was reported:, ...
(Date:8/21/2018)... FARMINGTON, Conn. (PRWEB) , ... August 20, 2018 ... ... and medical devices, there are many challenges to consider. Designers must ensure what ... In this webinar, we will explore some best practices in flow path design ...
Breaking Biology News(10 mins):
(Date:9/7/2018)... (PRWEB) , ... September 06, 2018 , ... ... a fatal neuromuscular disease, has been validated to be as effective as manual ... of Dystrophin Staining in Frozen Muscle Biopsies,” was published in the Archives of ...
(Date:8/31/2018)... (PRWEB) , ... August 29, 2018 , ... ... Professorships at both the University of Southampton and the Institute of Industrial Science, ... intelligence at sea can dramatically accelerate the exploration and study of hard to ...
(Date:8/29/2018)... , ... August 28, 2018 , ... Cognition Corporation ... full lineup of talks for NAVIGATE2018 . , Ryan Ward, Director of ... Cognition’s annual user conference. An experienced engineer and manager with Zimmer Biomet for almost ...
(Date:8/29/2018)... ... August 28, 2018 , ... LabRoots , the ... the world, is proud to announce the launch of a new gamification feature, allowing ... chance to win one of LabRoots most popular shirts. , Throughout each month, LabRoots ...
Breaking Biology Technology:
Cached News: