HOME >> BIOLOGY >> NEWS
Malaria -- Effective insecticide-repellent synergy against mosquito vectors

The mosquitoes responsible for malaria transmission to humans belong to the Anopheles genus. One of the best known and most extensively studied is Anopheles gambiae, Africas principal malaria vector. The protection recommended by the World Health Organization for people at risk from this devastating disease is the use of mosquito nets impregnated with pyrethroids, of low toxicity for mammals and highly active against mosquitoes. Unfortunately, excessive and inappropriate use of this family of insecticide, particularly by spraying, has induced a disturbing rise in the number of resistant individuals in the Anopheles populations. The mosquito nets treated with pyrethroids can therefore lose their effectiveness. It is therefore essential to devise new control strategies against these malaria vectors that are resistant to these insecticides.

IRD researchers and their partners (1) obtained encouraging results by combining a non-pyrethroid insecticide, propoxur, and a repellent, N,N-diethyl toluamide (DEET). They based their investigations on previous work which had revealed a strong synergy between the two components. A combination of the two had proved to be much more effective than the straightforward addition of their respective properties. Mosquito nets soaked with this mixture had a lethal power and irritant effect that inhibited the mosquitoes from biting. Moreover, the mosquitoes are hit by a powerful paralysing action, known as the knockdown effect (3), on contact with the mixture. The mortality rates determined were satisfactory, in that they equalled those obtained by using deltamethrin, a commonly-used synthetic pyrethroid, highly effective against mosquitoes.

The researchers tested two mixtures composed of a non-pyrethroid insecticide of the organophosphate family, combined with either a standard repellent, DEET, or with a new-generation synthetic repellent. Both of these mixtures show a strong synergy in the resulting lethal and paralysing
'"/>

Contact: Gregory Flechet
fichesactu@paris.ird.fr
33-014-803-7607
Institut de Recherche Pour le Dveloppement
17-Jul-2007


Page: 1 2 3

Related biology news :

1. Malaria-resistant mosquitoes battle disease with molecular warhead
2. Malaria and Epstein-Barr virus linked to pediatric cancer in Africa
3. Malaria in pregnancy: What can the social sciences contribute?
4. Malaria: The right vaccine in the right place?
5. PATH Malaria Vaccine Initiative announces partnership to develop novel malaria vaccine
6. 20 Years of Malaria Research: Outcomes and Perspectives
7. Malaria poses additional risks for first-time mothers
8. Malaria drug may treat metabolic syndromes many symptoms
9. Malaria: Efficacy of monotherapies in Cameroon
10. Malaria, potato famine pathogen share surprising trait
11. Malaria parasite impairs key immune system cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/9/2019)... ... November 08, 2019 , ... SiteSeer Technologies, creator of SiteSeer Professional ... new client and user of SiteSeer. The boutique real estate developer of single and ... use SiteSeer to supplement its own analysis of markets. , Geoffrey Kerth, manager ...
(Date:11/6/2019)... Mich. (PRWEB) , ... November 06, 2019 , ... ... Mastermind® version 2.0 today. The Genomic Search Engine now includes the ability ... functionality will further accelerate diagnosis of patients with genetic and rare diseases. , ...
(Date:10/30/2019)... CUMBERLAND FORESIDE, Maine (PRWEB) , ... October 29, ... ... UC4 linearity and calibration verification kits, for SIEMENS ATELLICA® analyzers, Order Numbers 701sa ... GLU, K, MG, NA, PHOS, UA, UTP, and UUN. , Each VALIDATE® kit, ...
Breaking Biology News(10 mins):
(Date:11/12/2019)... ... November 12, 2019 , ... ... solutions for biopharmaceutical R&D, today announced that Immatics Biotechnologies , a ... Genedata Biologics® to streamline their R&D operations related to the discovery ...
(Date:11/6/2019)... ... ... Diversified Technologies, Inc. has introduced a PEF production system for ... processing. , The DTI Industrial PEF Unit can pre-treat whole pieces of fruits and ... up to 50% and achieve up to an 80% reduction of drying energy. ...
(Date:11/2/2019)... ... October 31, 2019 , ... A ... communicating with each other: study managers, principal investigators, supply chain managers, manufacturers, IRT, ... is not informed of the latest data, potentially leading to patient risk. , ...
(Date:10/29/2019)... ... ... CaroGen Corporation , a biotechnology company, today announced three distinguished additions to ... MD, of Brown University , Dr. Steve Projan, PhD, FAAM, formerly of ... Wayne State University, formerly a professor at Yale University School of Medicine ...
Breaking Biology Technology:
Cached News: