HOME >> BIOLOGY >> NEWS
Malaria: Efficacy of monotherapies in Cameroon

stant strains observed in the north than in the south of Cameroon, complement the results of clinical investigations. The research team has since then launched similar work, focused especially on the gene for resistance to sulfadoxine, the other constituent of the sulfadoxine-pyrimethamine mixture.

The molecular approach, adapted to the varied epidemiological backgrounds that prevail in Cameroon, is therefore highly promising as a tool for tracking the evolution of resistance to monotherapies and thus for helping to improve malaria control strategies.

(1) Cameroon, with a surface area of 475 442 km2, is situated deep in the Gulf of Guinea, a region where Central Africa and West Africa meet. This geographical situation explains the great variety of climates and landscapes which make the country a kind of "Africa in miniature" (www.diplomatie.gouv.fr/fr/payszones- geo_833/cameroun_361/presentation-ducameroun_ 946/geographie_8432.html). In the north, dominated by vast plains, malaria transmission is seasonal. In the south, characterized by the presence of vast forest, it occurs continuously and intensively.

(2) In the standard surveys on therapeutic efficiency, just one drug or a single combination was tested simultaneously, in each patient and each locality, by a specialist mobile team. In the north of Cameroon where transmission is seasonal, this team's expeditions into the field had to be carefully planned. However, in the genetic approach, the collection of capillary blood on absorbent paper does not require any specialized team. A local team of local care providers gathers all samples together and sends them to the laboratory. The search for specific resistance markers can be carried on at the same time for several substances in uniform conditions.


'"/>

Contact: Marie Guillaume-Signoret
fichesactu@paris.ird.fr
33-014-803-7607
Institut de Recherche Pour le Dveloppement
13-Oct-2006


Page: 1 2 3

Related biology news :

1. Malaria: The right vaccine in the right place?
2. Efficacy of once-daily Avelox for complicated abdominal infections highlighted at ICAAC

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/2/2020)... ... July 01, 2020 , ... ... 1a findings of Neihulizumab, a biologic for the treatment of steroid-refractory acute graft-versus-host ... by hemato-oncologist Dr. Paul J Martin of the Fred Hutchinson Cancer Research Center, ...
(Date:7/1/2020)... ... July 01, 2020 , ... Cure Glioblastoma, a registered ... common and aggressive adult brain cancer—announced today the appointments of its first Senior ... with supporting the organization’s initiatives and overall vision. , "Senior Fellows are more ...
(Date:6/25/2020)... Mass. (PRWEB) , ... June 24, 2020 , ... ... of cloud-based enterprise software and software-driven clinical data services that accelerate drug development, ... for low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet Products ... three different materials for use with CRM, neurostimulation, vascular, and related devices. , ... meet specific design requirements, performance, and cost criteria; especially where solid wire is ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... the top radiation centers in 16 countries, has reached its 20th anniversary of ... now in routine use at top universities including University of Pennsylvania, University of ...
(Date:7/18/2020)... ... 2020 , ... After research model surgery and catheter implantation, the long journey ... the beginning of a successful study, while protecting and accessing the catheter or device ... of Surgery from Envigo in a live webinar on Wednesday, ...
(Date:7/18/2020)... ... July 17, 2020 , ... ... for the life sciences and food industries, is pleased to announce that Charles ... Research – Business Development. , Charles is an accomplished and results-driven sales executive ...
Breaking Biology Technology:
Cached News: