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Mapping system tells skin cells whether to become scalp, palm tissues, Stanford study finds

to be important in patterning the early embryo.

Rinn and his colleagues speculate that some of these processes may require more specific location indicators than the three they've currently identified. It's possible that additional cues may be provided by variations in gene expression levels too subtle to be detected in their current study. Alternatively, cell types other than fibroblasts or endothelial cells may express signals that further refine the current rough map. Finally, it's possible that adults simply don't need the same level of precision mapping as a developing embryo, and they stop broadcasting the finer points of the signal when it's no longer necessary.


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Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
2-Aug-2006


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