March of Dimes awards $250,000 prize to research pioneer

WHITE PLAINS, N.Y. MAY 1, 2006 -- For explaining how a tiny protein plays a major role in our lives by helping to regulate many crucial processes in human cells, Alexander Varshavsky, Ph.D., has been chosen as the 2006 recipient of the March of Dimes Prize in Developmental Biology, to be awarded May 1 in San Francisco, California.

The March of Dimes Prize is a cash award of $250,000 and a silver medal in the design of the Roosevelt dime, in honor of President Franklin Delano Roosevelt, who founded the March of Dimes.

Dr. Varshavsky, the Howard and Gwen Laurie Smits Professor of Cell Biology in the Division of Biology at the California Institute of Technology, has been credited by his peers with co-founding the field of ubiquitin research and ushering it into the age of molecular genetics. His pioneering studies in the 1980s brought to light the remarkably diverse and important biological functions of the ubiquitin system.

Ubiquitin (from the Latin ubique meaning "everywhere," the source of the word "ubiquitous"), is a protein found in every cell of all living things, from yeast to human beings. It attaches itself to many other proteins in cells specifically those proteins that have outlived their purpose, or are abnormal, or must be destroyed to regulate their levels in a cell. Ubiquitin marks these proteins for destruction by a protein-degrading molecular "machine" called the proteasome.

Dr. Varshavsky's laboratory discovered that ubiquitin plays important roles in the cell cycle, DNA repair, protein synthesis, transcriptional regulation, and responses to stress. Dr. Varshavsky and coworkers also discovered "degradation" signals in short-lived proteins, the source of ubiquitin's selectivity as well as a fundamental property of the ubiquitin system that makes it possible to remodel multi-subunit proteins by destroying them partially, "one subunit at a time." His work revealed that the regulation of cells through selective

Contact: Elizabeth Lynch
March of Dimes Birth Defects Foundation

Page: 1 2

Related biology news :

1. March of the giant penguins
2. March of Dimes awards $250K prize to stem cell research, reproductive biology pioneers
3. ACS News Service Weekly PressPac -- March 28, 2007
4. ACS News Service Weekly PressPac -- March 21, 2007
5. National Academies advisory: March 27 release of report on metagenomics
6. JCI table of contents -- March 22, 2007
7. Other highlights from the March 21 JNCI
8. Story tips from the Department of Energys Oak Ridge National Laboratory, March 2007
9. Research and program highlights of the 2007 Annual Clinical Genetics Meeting, March 21-25, 2007
10. ACS News Service Weekly PressPac -- March. 14, 2007
11. Pioneering researcher Dr. Kenneth Lyons Jones receives genetics award from March of Dimes

Post Your Comments:

(Date:11/26/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/jwkl9t/capacitive ) has announced ... Technology and Patent Infringement Risk Analysis" report to ... --> Fingerprint sensors using capacitive technology represent a ... vendor Idex forecasts an increase of 360% of the ... of the fingerprint sensor market between 2014 and 2017 ...
(Date:11/19/2015)... VIEW, Calif. , Nov. 19, 2015  Based ... market, Frost & Sullivan recognizes BIO-key with the 2015 ... Leadership. Each year, Frost & Sullivan presents this award ... product line catering to the needs of the market ... the product line meets and expands on customer base ...
(Date:11/18/2015)... , Nov. 18, 2015  As new scientific ... children, doctors and other healthcare providers face challenges in ... families and patients. In addition, as more children continue ... a patient,s adulthood and old age. John ... The Children,s Hospital of Philadelphia (CHOP) . ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... SAN DIEGO , Nov. 25, 2015  Neurocrine ... Kevin Gorman , President and CEO of Neurocrine ... Jaffray Healthcare Conference in New York ... encouraged to visit the website approximately 5 minutes prior ... software.  A replay of the presentation will be available ...
(Date:11/25/2015)... ... November 25, 2015 , ... A long-standing ... Aerospace Professionals (OPBAP) has been formalized with the signing of a Memorandum of ... with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn Tuesday, November 24, ...
(Date:11/25/2015)... 25, 2015 The Global ... a professional and in-depth study on the current ... (Logo: http://photos.prnewswire.com/prnh/20141014/710132 ) , The ... including definitions, classifications, applications and industry chain structure. ... international markets including development trends, competitive landscape analysis, ...
(Date:11/24/2015)... , Nov. 24, 2015  Asia-Pacific (APAC) holds ... organisation (CRO) market. The trend of outsourcing to ... margins but higher volume share for the region ... scale, however, margins in the CRO industry will ... Market ( http://www.frost.com/sublib/display-report.do?id=P86A-01-00-00-00&src=PR ), finds that the ...
Breaking Biology Technology:
Cached News: