HOME >> BIOLOGY >> NEWS
March of Dimes awards $250,000 prize to research pioneer

WHITE PLAINS, N.Y. MAY 1, 2006 -- For explaining how a tiny protein plays a major role in our lives by helping to regulate many crucial processes in human cells, Alexander Varshavsky, Ph.D., has been chosen as the 2006 recipient of the March of Dimes Prize in Developmental Biology, to be awarded May 1 in San Francisco, California.

The March of Dimes Prize is a cash award of $250,000 and a silver medal in the design of the Roosevelt dime, in honor of President Franklin Delano Roosevelt, who founded the March of Dimes.

Dr. Varshavsky, the Howard and Gwen Laurie Smits Professor of Cell Biology in the Division of Biology at the California Institute of Technology, has been credited by his peers with co-founding the field of ubiquitin research and ushering it into the age of molecular genetics. His pioneering studies in the 1980s brought to light the remarkably diverse and important biological functions of the ubiquitin system.

Ubiquitin (from the Latin ubique meaning "everywhere," the source of the word "ubiquitous"), is a protein found in every cell of all living things, from yeast to human beings. It attaches itself to many other proteins in cells specifically those proteins that have outlived their purpose, or are abnormal, or must be destroyed to regulate their levels in a cell. Ubiquitin marks these proteins for destruction by a protein-degrading molecular "machine" called the proteasome.

Dr. Varshavsky's laboratory discovered that ubiquitin plays important roles in the cell cycle, DNA repair, protein synthesis, transcriptional regulation, and responses to stress. Dr. Varshavsky and coworkers also discovered "degradation" signals in short-lived proteins, the source of ubiquitin's selectivity as well as a fundamental property of the ubiquitin system that makes it possible to remodel multi-subunit proteins by destroying them partially, "one subunit at a time." His work revealed that the regulation of cells through selective
'"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Birth Defects Foundation
10-Apr-2006


Page: 1 2

Related biology news :

1. March of the giant penguins
2. March of Dimes awards $250K prize to stem cell research, reproductive biology pioneers
3. ACS News Service Weekly PressPac -- March 28, 2007
4. ACS News Service Weekly PressPac -- March 21, 2007
5. National Academies advisory: March 27 release of report on metagenomics
6. JCI table of contents -- March 22, 2007
7. Other highlights from the March 21 JNCI
8. Story tips from the Department of Energys Oak Ridge National Laboratory, March 2007
9. Research and program highlights of the 2007 Annual Clinical Genetics Meeting, March 21-25, 2007
10. ACS News Service Weekly PressPac -- March. 14, 2007
11. Pioneering researcher Dr. Kenneth Lyons Jones receives genetics award from March of Dimes

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/2/2016)... Feb. 2, 2016 Checkpoint Inhibitors for ... Market Are you interested in the future ... for checkpoint inhibitors. Visiongain,s report gives those predictions ... and national level. Avoid falling behind in ... opportunities and revenues those emerging cancer therapies can ...
(Date:2/1/2016)...  Today, the first day of American Heart Month, ... a first of its kind workplace health solution that ... the first application of Watson ... and Welltok will create a new offering that combines ... delivered on Welltok,s health optimization platform. The effort is ...
(Date:1/25/2016)... , Jan. 25, 2016  Glencoe Software, the world-leading ... and publication industries, will provide the data management solution ... (NPSC). ... Phenotypic analysis measures the ... organisms, allowing comparisons between states such as health and ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... - New FDA action date of July 22, ... July 22, 2016   --> - ... 2016   - Lifitegrast has the potential to be ... of signs and symptoms of dry eye disease in adults ... only product approved in the U.S. in the past decade indicated for the treatment of ...
(Date:2/4/2016)... N.J. , Feb. 4, 2016  CytoSorbents ... immunotherapy leader commercializing its flagship CytoSorb® blood filter ... surgery patients around the world, announced that CEO ... present at the Source Capital Group,s 2016 Disruptive ... update on the company.  Conference ...
(Date:2/4/2016)... Feb. 4, 2016 Sinovac Biotech Ltd. ("Sinovac" ... provider of biopharmaceutical products in China ... board of directors received on February 4, 2016 a ... a consortium comprised of PKU V-Ming ( Shanghai ... Ltd., CICC Qianhai Development ( Shenzhen ) ...
(Date:2/3/2016)... , Feb. 3, 2016  Discovery Laboratories, ... focused on developing aerosolized KL4 surfactant therapies for ... Directors has approved an inducement award as a ... , its newly appointed President and Chief Executive ... Compensation Committee on February 1, 2016 and granted ...
Breaking Biology Technology:
Cached News: