HOME >> BIOLOGY >> NEWS
March of Dimes awards $250,000 prize to research pioneer

WHITE PLAINS, N.Y. MAY 1, 2006 -- For explaining how a tiny protein plays a major role in our lives by helping to regulate many crucial processes in human cells, Alexander Varshavsky, Ph.D., has been chosen as the 2006 recipient of the March of Dimes Prize in Developmental Biology, to be awarded May 1 in San Francisco, California.

The March of Dimes Prize is a cash award of $250,000 and a silver medal in the design of the Roosevelt dime, in honor of President Franklin Delano Roosevelt, who founded the March of Dimes.

Dr. Varshavsky, the Howard and Gwen Laurie Smits Professor of Cell Biology in the Division of Biology at the California Institute of Technology, has been credited by his peers with co-founding the field of ubiquitin research and ushering it into the age of molecular genetics. His pioneering studies in the 1980s brought to light the remarkably diverse and important biological functions of the ubiquitin system.

Ubiquitin (from the Latin ubique meaning "everywhere," the source of the word "ubiquitous"), is a protein found in every cell of all living things, from yeast to human beings. It attaches itself to many other proteins in cells specifically those proteins that have outlived their purpose, or are abnormal, or must be destroyed to regulate their levels in a cell. Ubiquitin marks these proteins for destruction by a protein-degrading molecular "machine" called the proteasome.

Dr. Varshavsky's laboratory discovered that ubiquitin plays important roles in the cell cycle, DNA repair, protein synthesis, transcriptional regulation, and responses to stress. Dr. Varshavsky and coworkers also discovered "degradation" signals in short-lived proteins, the source of ubiquitin's selectivity as well as a fundamental property of the ubiquitin system that makes it possible to remodel multi-subunit proteins by destroying them partially, "one subunit at a time." His work revealed that the regulation of cells through selective
'"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Birth Defects Foundation
10-Apr-2006


Page: 1 2

Related biology news :

1. March of the giant penguins
2. March of Dimes awards $250K prize to stem cell research, reproductive biology pioneers
3. ACS News Service Weekly PressPac -- March 28, 2007
4. ACS News Service Weekly PressPac -- March 21, 2007
5. National Academies advisory: March 27 release of report on metagenomics
6. JCI table of contents -- March 22, 2007
7. Other highlights from the March 21 JNCI
8. Story tips from the Department of Energys Oak Ridge National Laboratory, March 2007
9. Research and program highlights of the 2007 Annual Clinical Genetics Meeting, March 21-25, 2007
10. ACS News Service Weekly PressPac -- March. 14, 2007
11. Pioneering researcher Dr. Kenneth Lyons Jones receives genetics award from March of Dimes

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: March Dimes awards prize research pioneer

(Date:12/4/2014)... Dec. 3, 2014  Crossmatch™, a leading provider ... its DigitalPersona ® Pro Enterprise software and ... deployed throughout First Bank branch locations in ... Carolina and Virginia. First Bank, a progressive ... Pines, North Carolina , selected the Crossmatch ...
(Date:11/21/2014)...  Earlier this year Donald Spector , Chairman ... of the most prolific inventors in the world, got ... Smartphones to third party agencies. Spector envisioned this technology ... the earliest known patents in this area. Now major ... child care, elder care and hospital applications. This technology ...
(Date:11/18/2014)... , Nov. 18, 2014  The Secure Identity ... Association today jointly announce the formation of The ... of its Identity and Biometric Entry and ... Framework received official support from BORDERPOL, the international ... improve and provide expertise regarding border security, traveler ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
Cached News: