HOME >> BIOLOGY >> NEWS
Mechanism to organize nervous system conserved in evolution

A study led by University of California, San Diego biologists suggests that, contrary to the prevailing view, the process in early development that partitions the nervous system in fruit flies and vertebrates, like humans, evolved from a common ancestor.

In the September 12 issue of the journal Public Library of Science Biology, the researchers report that in both fruit fly and chick embryos proteins called BMPs play similar roles in telling cells in the early embryo to switch certain genes on and off, specifying the identity of the cells making up the three primary subdivisions of the central nervous system. The findings suggest a unified model of early neural development in which at least part of the mechanism for creating neural patterning has been preserved from a shared ancestral organism that lived over 500 million years ago.

"We have provided the first evidence for a common role of BMPs in establishing the pattern of gene expression along the dorsal-ventral axis of the nervous system of vertebrates and invertebrates," said Ethan Bier, a professor of biology at UCSD and senior author on the study. "Our results suggest that this process has been conserved from a common ancestor rather than evolving separately as had been previously believed."

Early in the development of a complex organism, when it is a ball of indistinguishable cells, BMP gradients are responsible for partitioning embryos into neural and non-neural tissue. During this phase, often referred to as neural induction, high levels of BMPs in non-neural regions actively suppress neural development. This role of BMPs is one of the best examples of a conserved evolutionary process.

However, it has been less clear whether BMPs also play a common role in further subdividing the nerve tissue into three distinct regions. Although the so-called neural identity genes get switched on in a similar pattern in relation to the BMP source, it has been speculated that disti
'"/>

Contact: Sherry Seethaler
sseethaler@ucsd.edu
858-534-4656
University of California - San Diego
11-Sep-2006


Page: 1 2 3

Related biology news :

1. Mechanism of microRNAs deciphered
2. Mechanisms involved with tumor relapse identified
3. Mechanism for memory revealed in neurons of electric fish
4. Mechanism for Epstein-Barr virus proteins role in blood cancers discovered
5. Mechanism of new sudden-death arrhythmia detailed
6. Mechanism regulating tooth shape formulation found
7. Mechanism proposed for link between RU-486 and fatal infections
8. Mechanism for the captation of nutrients in plants- unknown to date
9. Mechanism discovered for muscle wasting seen in diabetes, AIDS and other diseases
10. Brains hearing center may reorganize after implant of cochlear device
11. With record resolution and sensitivity, tool images how life organizes in a cell membrane

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... July 16, 2020 , ... A ... of the Invictus Medical Neoasis™ active noise control device to attenuate typical noises ... the Neoasis™ device attenuated the alarm sounds from patient monitors, ventilators and other ...
(Date:7/10/2020)... ... July 08, 2020 , ... Overcoming ... Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, 2020 • 1:30 p.m.-3:00 p.m. ... what is the most effective way to complete one? Will the study comply ...
(Date:7/4/2020)... ... , ... Aesthetics Biomedical (ABM), a leading aesthetics product development ... the products and treatments developed, but also the dedicated team behind the brands ... built by ABM have received several honors already for 2020, each of which ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... , ... R3 Stem Cell International is now offering patients the opportunity to ... total, patients may choose which extremities they would like treated. , Several studies have ... 2016). At R3 International, umbilical cord tissue is obtained from a lab with a ...
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet Products has introduced new ... for use with CRM, neurostimulation, vascular, and related devices. , Anomet Medical ... requirements, performance, and cost criteria; especially where solid wire is limited. Typical configurations ...
(Date:7/31/2020)... , ... July 29, 2020 , ... ... of the top radiation centers in 16 countries, has reached its 20th anniversary ... is now in routine use at top universities including University of Pennsylvania, University ...
(Date:7/18/2020)... ... , ... After research model surgery and catheter implantation, the long journey of ... beginning of a successful study, while protecting and accessing the catheter or device post-surgery ... Surgery from Envigo in a live webinar on Wednesday, August ...
Breaking Biology Technology:
Cached News: