HOME >> BIOLOGY >> NEWS
Mechanism to organize nervous system conserved in evolution

A study led by University of California, San Diego biologists suggests that, contrary to the prevailing view, the process in early development that partitions the nervous system in fruit flies and vertebrates, like humans, evolved from a common ancestor.

In the September 12 issue of the journal Public Library of Science Biology, the researchers report that in both fruit fly and chick embryos proteins called BMPs play similar roles in telling cells in the early embryo to switch certain genes on and off, specifying the identity of the cells making up the three primary subdivisions of the central nervous system. The findings suggest a unified model of early neural development in which at least part of the mechanism for creating neural patterning has been preserved from a shared ancestral organism that lived over 500 million years ago.

"We have provided the first evidence for a common role of BMPs in establishing the pattern of gene expression along the dorsal-ventral axis of the nervous system of vertebrates and invertebrates," said Ethan Bier, a professor of biology at UCSD and senior author on the study. "Our results suggest that this process has been conserved from a common ancestor rather than evolving separately as had been previously believed."

Early in the development of a complex organism, when it is a ball of indistinguishable cells, BMP gradients are responsible for partitioning embryos into neural and non-neural tissue. During this phase, often referred to as neural induction, high levels of BMPs in non-neural regions actively suppress neural development. This role of BMPs is one of the best examples of a conserved evolutionary process.

However, it has been less clear whether BMPs also play a common role in further subdividing the nerve tissue into three distinct regions. Although the so-called neural identity genes get switched on in a similar pattern in relation to the BMP source, it has been speculated that disti
'"/>

Contact: Sherry Seethaler
sseethaler@ucsd.edu
858-534-4656
University of California - San Diego
11-Sep-2006


Page: 1 2 3

Related biology news :

1. Mechanism of microRNAs deciphered
2. Mechanisms involved with tumor relapse identified
3. Mechanism for memory revealed in neurons of electric fish
4. Mechanism for Epstein-Barr virus proteins role in blood cancers discovered
5. Mechanism of new sudden-death arrhythmia detailed
6. Mechanism regulating tooth shape formulation found
7. Mechanism proposed for link between RU-486 and fatal infections
8. Mechanism for the captation of nutrients in plants- unknown to date
9. Mechanism discovered for muscle wasting seen in diabetes, AIDS and other diseases
10. Brains hearing center may reorganize after implant of cochlear device
11. With record resolution and sensitivity, tool images how life organizes in a cell membrane

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2021)... ... March 25, 2021 , ... Phlexglobal announced ... Planet Group, has selected Phlexglobal and its innovative regulatory SaaS software, PhlexSubmission, as ... a comprehensive review of five regulatory software companies, with the review team including ...
(Date:3/27/2021)... ... 25, 2021 , ... The 2021 Virtual Conference on Clinical Trial Supply-Europe ... More and more, clinical trial supply conferences are featuring speakers and forums that ... Asymmetrex’s founder and CEO, James L. Sherley, M.D., Ph.D., presented a talk ...
(Date:3/23/2021)... ... March 23, 2021 , ... G-CON Manufacturing (G-CON), the ... by Matica Biotechnology (Matica Bio), a contract development and manufacturing organization (CDMO) specializing ... the cleanroom build out for its new GMP production facility in College Station, ...
Breaking Biology News(10 mins):
(Date:3/27/2021)... ... March 24, 2021 , ... ... Life Sciences and Healthcare firms of all sizes, adds depth to its team ... specialist. Pardillo, who earned his doctorate in computational chemistry from Florida International University ...
(Date:3/27/2021)... ... March 24, 2021 , ... ABI Wellness, ... and reporting approach designed under CEO Mark Watson, today announced a webinar dedicated ... featuring guest speakers Dr. Cameron Clark, Neuropsychologist and Founder of Sharp Thinking, and ...
(Date:3/27/2021)... ... ... The Xtalks editorial team is pleased to announce the launch of the ... joined by editorial team members Ayesha Rashid, Sydney Perelmutter and Mira Nabulsi to discuss ... including insights from industry experts. , The Xtalks Life Science podcast will feature ...
(Date:3/23/2021)... Conn. (PRWEB) , ... March 23, 2021 , ... ... develops solutions for characterizing microbiome populations down to the strain level, recently unveiled ... applications. , Not all microbes are created equal: some are easy to ...
Breaking Biology Technology:
Cached News: