HOME >> BIOLOGY >> NEWS
Meconium: Baby's first stool may provide clues to fetal alcohol exposure

  • Fetal alcohol exposure is usually determined through self-reported maternal consumption.
  • New research shows that certain fatty acid ethyl esters (FAEEs) in meconium may provide dependable biomarkers of fetal alcohol exposure.
  • FAEEs ethyl linoleate and ethyl arachidonate appear particularly promising.

Fetal alcohol exposure is usually determined through self-reported maternal consumption. Self-reported drinking, however, is often an unreliable measure. Researchers have found that the presence of certain fatty acid ethyl esters (FAEEs) in meconium may provide a dependable biomarker of fetal alcohol exposure.

Results are published in the July 2006 issue of Alcoholism: Clinical & Experimental Research

"There are only a few biomarkers that indicate if an infant has been exposed to alcohol during pregnancy, and most of them are not strictly associated with alcohol use," said Enrique M. Ostrea, Jr., professor of pediatrics at Wayne State University. "In this study, we have found a direct association between the presence of certain FAEEs and alcohol use." Ostrea, Jr. is also the corresponding author for the study.

When people drink alcohol, it combines with certain fats in the body known as fatty acids, and FAEEs are formed. These "markers" are either deposited in tissues or, in the case of a growing fetus, in fetal urine or meconium.

"People characteristically underreport the amount of alcohol they drink," said Michael Laposata, director of clinical laboratories at the Massachusetts General Hospital and professor of pathology at Harvard Medical School. "One can measure blood alcohol but it disappears from the blood relatively quickly after drinking stops, so only very recent intake can be documented. FAEEs are 'long-term markers' of alcohol intake because they stay much longer in blood than alcohol itself and, in this case, accumulate in meconium."

For this study, resear
'"/>


25-Jun-2006


Page: 1 2 3

Related biology news :

1. Babys helping hands
2. Babys genes affect moms cholesterol levels
3. Saudi Arabias KAUST names WHOI first research partner
4. Which came first, the moth or the cactus?
5. In a first, Einstein scientists discover the dynamics of transcription in living mammalian cells
6. Seawater intrusion is the first cause of contamination of coastal aquifers
7. Camera-shy deer caught for first time
8. CTRC enrolls first patients in novel phase II study for sarcoma -- living virus destroys cancer cell
9. New joint replacement material developed at MGH put to first clinical use
10. Liverpool amongst first in UK to install unique DNA sequencing technology
11. A first-principles model of early evolution

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
(Date:3/24/2017)... Research and Markets has announced the addition of the "Global ... to 2025" report to their offering. ... The Global Biometric Vehicle Access System Market ... the next decade to reach approximately $1,580 million by 2025. ... for all the given segments on global as well as regional ...
(Date:3/23/2017)... 23, 2017 Research and Markets has announced ... & Trends - Industry Forecast to 2025" report to their ... The ... CAGR of around 8.8% over the next decade to reach approximately ... the market estimates and forecasts for all the given segments on ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that give ... Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los Angeles ...
(Date:10/10/2017)... CRUZ, Calif. , Oct. 10, 2017 ... grant from the NIH to develop RealSeq®-SC (Single Cell), ... kit for profiling small RNAs (including microRNAs) from single ... Analysis Program highlights the need to accelerate development of ... "New techniques for measuring ...
(Date:10/9/2017)... ... , ... The award-winning American Farmer television series will feature 3 Bar Biologics ... at 8:30aET on RFD-TV. , With global population estimates nearing ten billion people ... to feed a growing nation. At the same time, many of our valuable resources ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... and applications consulting for microscopy and surface analysis, Nanoscience Instruments is now ... Analytical offers a broad range of contract analysis services for advanced applications. ...
Breaking Biology Technology:
Cached News: