HOME >> BIOLOGY >> NEWS
Microscopic brain imaging in the palm of your hand

Researchers at Stanford University have demonstrated a promising, minimally invasive optical technique that can capture micron-scale images from deep in the brains of live subjects. The method, called two-photon microendoscopy, combines a pair of powerful optical and mechanical techniques into one device that fits in the palm of the hand. The results appear in the September 1, 2005 issue of Optics Letters, a journal published by the Optical Society of America.

Researchers want to image individual cells inside living subjects because it will give them insight into how cellular behavior gives rise to the properties of organisms as a whole. For instance, the nerve cells of the hippocampus region of the brain give rise to important mental processes such as learning and memory.

Imaging living cells below the surface has been difficult to accomplish using conventional techniques. Electron microscopy can't be used on living tissue, and optical (light) microscopy can't penetrate very deeply into tissue because light scatters as it travels through tissue near the surface. Thus traditionally microscopic images of the living brain have only been made near the surface. Yet researchers would like to know more about certain deep-tissue areas of the brain, which are critical to understanding Alzheimer's and Parkinson's disease, for example.

Scientists often use some form of fluorescence microscopy to image tissue. In conventional "one-photon" fluorescence imaging, the scientist injects a dye into tissue and then shines a bright light. The tissue fluoresces, or radiates, light of a different color in response. However, a problem with one-photon fluorescence is that the deep tissue causes the photons to ricochet, or scatter, as they return to the detector. The result is a background haze in the images, almost like viewing the sample through a cloud.

It's possible to get rid of background haze and reduce the scattering using two-photon fluore
'"/>

Contact: Ben Stein
bstein@aip.org
301-209-3091
American Institute of Physics
24-Aug-2005


Page: 1 2 3

Related biology news :

1. Microscopic jets, diamonds unlikely on Uranus, and amazing mosquito legs
2. Microscopic sea creatures provide foundation for gas sensors and other devices
3. Microscopic passengers to hitch ride on space shuttle
4. Invasion of the brain tumors
5. Preclinical study links gene to brain aneurysm formation
6. Gene variant is associated with brain anatomy, clinical course of ADHD
7. Human knowledge is based upon directed connectivity between brain areas
8. A sensory organ, not the brain, differentiates male and female behavior in some mammals
9. Reading ability protects brain from lead exposure
10. Strength of connections between brain regions may affect an adolescents response to peer influence
11. Females more prone to brain damage from alcohol abuse

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/18/2019)... ... June 18, 2019 , ... Cirrascale ... introduced Data Science Workstations-as-a-Service as part of its dedicated, multi-GPU, deep learning cloud ... Data Science Workstations feature NVIDIA® Quadro RTX™ GPUs for up to 260 teraflops ...
(Date:6/14/2019)... Va. (PRWEB) , ... June 14, 2019 , ... Molecular ... is estimated to be $8,760 million in 2019. Major segments that are expected ... These are all broken out and forecasted as segments in Kalorama’s The World ...
(Date:6/11/2019)... ... 12, 2019 , ... With a rapidly growing customer base ... Geneious Biologics platform as a premium hub for bioinformatics and computer programming capabilities. ... Geneious team has done an excellent job accommodating our specific data, resulting in ...
Breaking Biology News(10 mins):
(Date:5/2/2019)... ... 2019 , ... Stay on top of current hot topics through free webinars ... all webinars is free, so be sure to register today to save your place! ... to see our upcoming webinars: , CLINICAL TRIALS , May 7 – Oncology ...
(Date:5/2/2019)... ... May 02, 2019 , ... Boston Robotic Hair Restoration ... Gone are the days of painful hair transplant procedures. Boston Robotic Hair Restoration ... the only robotic intelligent solution to offer a minimally invasive procedure. With the ...
(Date:4/25/2019)... SAN FRANCISCO (PRWEB) , ... April 24, 2019 ... ... Intelligent Virtual Agents for sales and service organizations, today announced global ... contact center software providers and enterprises of all sizes to harness the power ...
(Date:4/16/2019)... ... April 16, 2019 , ... On April ... partner, the U.S. Army Center for Environmental Health Research (USACEHR), with an award ... , Blue Sources, a veteran-owned company located at the Frederick Innovative Technology Center, ...
Breaking Biology Technology:
Cached News: