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Modeling lung cancer

of BRaf(VE)-induced lung tumors to MEK inhibition is most likely because the tumors are at such an early stage of their development. Such observations further emphasize the need for early detection in human lung cancer, since the earlier a tumor is detected the more likely it is to be curable. However, MEK inhibitors may still be useful for late stage cancers, especially if used in conjunction with conventional chemotherapy, a question that McMahon and colleagues are planning to address in their next round of experiments.


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Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
12-Feb-2007


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